Gene name: HOS3
Reference locus (S288C): YPL116W
Gene biotype: protein_coding
Description: Histone deacetylase HOS3; Trichostatin A-insensitive homodimeric histone deacetylase (HDAC); specificity in vitro for histones H3, H4, H2A, and H2B; similar to Hda1p, Rpd3p, Hos1p, and Hos2p; deletion results in increased histone acetylation at rDNA repeats
Top 10 interactors (score): HOS2 (0.992); RPD3 (0.99); HOS1 (0.988); SIN3 (0.936); NSP1 (0.918); SNT1 (0.905); WHI5 (0.831); SET1 (0.825); NUP2 (0.824); HAT2 (0.819); HST2 (0.817); SIR2 (0.815); MSI1 (0.81); SMP1 (0.795); RLM1 (0.795); HST1 (0.786); HDA3 (0.782); HHT2 (0.772); GCN5 (0.769); HSL7 (0.757)
Homologues (species, bitscore): HDAC9 (Homo sapiens, 87.4); Hdac4 (Mus musculus, 87.4); LOC557486 (Danio rerio, 92.0); HDAC5 (Xenopus tropicalis, 84.0); HDAC6 (Drosophila melanogaster, 88.2); hda-6 (Caenorhabditis elegans, 94.4); HDA14 (Arabidopsis thaliana, 90.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:307245-309338:+ | gene-YPL116W_AKU4011 | rna-NM_001183930.1_AKU4011 | cds-NP_015209.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:513002-515095:+ | gene-YPL116W_BG1 | rna-NM_001183930.1_BG1 | cds-NP_015209.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:333251-335344:+ | gene-YPL116W_Bruggeman | rna-NM_001183930.1_Bruggeman | cds-NP_015209.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:329918-332011:+ | gene-YPL116W_CAT1 | rna-NM_001183930.1_CAT1 | cds-NP_015209.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:311318-313411:+ | gene-YPL116W_CBS1585 | rna-NM_001183930.1_CBS1585 | cds-NP_015209.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:325994-328087:+ | gene-YPL116W_CBS436 | rna-NM_001183930.1_CBS436 | cds-NP_015209.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:315987-318080:+ | gene-YPL116W_CBS6412 | rna-NM_001183930.1_CBS6412 | cds-NP_015209.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:307954-310047:+ | gene-YPL116W_CBS6413 | rna-NM_001183930.1_CBS6413 | cds-NP_015209.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:329555-331648:+ | gene-YPL116W_CENPK1137D | rna-NM_001183930.1_CENPK1137D | cds-NP_015209.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:305935-308028:+ | gene-YPL116W_EthanolRed | rna-NM_001183930.1_EthanolRed | cds-NP_015209.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:313527-315620:+ | gene-YPL116W_FaliES1 | rna-NM_001183930.1_FaliES1 | cds-NP_015209.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000007.1:50196-52289:- | gene-YPL116W_JAY291 | rna-NM_001183930.1_JAY291 | cds-NP_015209.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:324490-326583:+ | gene-YPL116W_MUCL30387 | rna-NM_001183930.1_MUCL30387 | cds-NP_015209.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:322761-324854:+ | gene-YPL116W_MUCL30388 | rna-NM_001183930.1_MUCL30388 | cds-NP_015209.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:304647-306740:+ | gene-YPL116W_MUCL39482 | rna-NM_001183930.1_MUCL39482 | cds-NP_015209.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:361890-363983:+ | gene-YPL116W_MUCL42920 | rna-NM_001183930.1_MUCL42920 | cds-NP_015209.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:329589-331682:+ | gene-YPL116W_NCIM3186 | rna-NM_001183930.1_NCIM3186 | cds-NP_015209.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:311100-313193:+ | gene-YPL116W_NCYC1407 | rna-NM_001183930.1_NCYC1407 | cds-NP_015209.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:318593-320686:+ | gene-YPL116W_PE2H3 | rna-NM_001183930.1_PE2H3 | cds-NP_015209.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:318216-320309:+ | gene-YPL116W_PE2H4 | rna-NM_001183930.1_PE2H4 | cds-NP_015209.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:329606-331699:+ | gene-YPL116W_S288C | rna-NM_001183930.1_S288C | cds-NP_015209.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000012.1:41981-44074:- | gene-YPL116W_SA1 | rna-NM_001183930.1_SA1 | cds-NP_015209.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:313325-315418:+ | gene-YPL116W_ThermosaccDry | rna-NM_001183930.1_ThermosaccDry | cds-NP_015209.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:328305-330398:+ | gene-YPL116W_VR1 | rna-NM_001183930.1_VR1 | cds-NP_015209.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:312650-314743:+ | gene-YPL116W_ZTW1 | rna-NM_001183930.1_ZTW1 | cds-NP_015209.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:314358-316451:+ | gene-YPL116W_Sparadoxus | rna-NM_001183930.1_Sparadoxus | cds-NP_015209.1_Sparadoxus | 91.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |