Gene name: HOS1
Reference locus (S288C): YPR068C
Gene biotype: protein_coding
Description: Class I histone deacetylase (HDAC) family member; deacetylates Smc3p on lysine residues at anaphase onset; has sequence similarity to Hda1p, Rpd3p, Hos2p, and Hos3p; interacts with the Tup1p-Ssn6p corepressor complex
Top 10 interactors (score): SIN3 (0.992); HOS3 (0.988); HAT2 (0.97); SMC3 (0.966); SNT1 (0.954); UBC9 (0.947); HOS2 (0.934); MSI1 (0.923); FMS1 (0.916); NSP1 (0.902); ECO1 (0.888); HTZ1 (0.886); SIF2 (0.874); HDA1 (0.871); HTB2 (0.862); SMT3 (0.855); HTA1 (0.847); HTB1 (0.827); HTA2 (0.824); HHT2 (0.819)
Homologues (species, bitscore): HDAC1 (Homo sapiens, 179.1); Hdac1 (Mus musculus, 179.1); hdac1 (Danio rerio, 181.4); hdac8 (Xenopus tropicalis, 182.2); Rpd3 (Drosophila melanogaster, 180.3); hda-1 (Caenorhabditis elegans, 174.1); HDA9 (Arabidopsis thaliana, 169.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:654619-656031:- | gene-YPR068C_AKU4011 | rna-NM_001184165.1_AKU4011 | cds-NP_015393.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:241660-243072:+ | gene-YPR068C_BG1 | rna-NM_001184165.1_BG1 | cds-NP_015393.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:732286-733698:- | gene-YPR068C_Bruggeman | rna-NM_001184165.1_Bruggeman | cds-NP_015393.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:775730-777142:- | gene-YPR068C_CAT1 | rna-NM_001184165.1_CAT1 | cds-NP_015393.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:658307-659719:- | gene-YPR068C_CBS1585 | rna-NM_001184165.1_CBS1585 | cds-NP_015393.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:672672-674084:- | gene-YPR068C_CBS436 | rna-NM_001184165.1_CBS436 | cds-NP_015393.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:662054-663466:- | gene-YPR068C_CBS6412 | rna-NM_001184165.1_CBS6412 | cds-NP_015393.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:655253-656665:- | gene-YPR068C_CBS6413 | rna-NM_001184165.1_CBS6413 | cds-NP_015393.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:682904-684316:- | gene-YPR068C_CENPK1137D | rna-NM_001184165.1_CENPK1137D | cds-NP_015393.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:981813-983225:- | gene-YPR068C_EthanolRed | rna-NM_001184165.1_EthanolRed | cds-NP_015393.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:660450-661862:- | gene-YPR068C_FaliES1 | rna-NM_001184165.1_FaliES1 | cds-NP_015393.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000446.1:32392-33804:- | gene-YPR068C_JAY291 | rna-NM_001184165.1_JAY291 | cds-NP_015393.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:673546-674958:- | gene-YPR068C_MUCL30387 | rna-NM_001184165.1_MUCL30387 | cds-NP_015393.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:672251-673663:- | gene-YPR068C_MUCL30388 | rna-NM_001184165.1_MUCL30388 | cds-NP_015393.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:651564-652976:- | gene-YPR068C_MUCL39482 | rna-NM_001184165.1_MUCL39482 | cds-NP_015393.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:714387-715799:- | gene-YPR068C_MUCL42920 | rna-NM_001184165.1_MUCL42920 | cds-NP_015393.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:682924-684336:- | gene-YPR068C_NCIM3186 | rna-NM_001184165.1_NCIM3186 | cds-NP_015393.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:659492-660904:- | gene-YPR068C_NCYC1407 | rna-NM_001184165.1_NCYC1407 | cds-NP_015393.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:665695-667107:- | gene-YPR068C_PE2H3 | rna-NM_001184165.1_PE2H3 | cds-NP_015393.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:665343-666755:- | gene-YPR068C_PE2H4 | rna-NM_001184165.1_PE2H4 | cds-NP_015393.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:682941-684353:- | gene-YPR068C_S288C | rna-NM_001184165.1_S288C | cds-NP_015393.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000026.1:16337-17749:+ | gene-YPR068C_SA1 | rna-NM_001184165.1_SA1 | cds-NP_015393.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:660225-661637:- | gene-YPR068C_ThermosaccDry | rna-NM_001184165.1_ThermosaccDry | cds-NP_015393.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:676369-677781:- | gene-YPR068C_VR1 | rna-NM_001184165.1_VR1 | cds-NP_015393.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:659448-660860:- | gene-YPR068C_ZTW1 | rna-NM_001184165.1_ZTW1 | cds-NP_015393.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:660218-661630:- | gene-YPR068C_Sparadoxus | rna-NM_001184165.1_Sparadoxus | cds-NP_015393.1_Sparadoxus | 86.8 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |