Gene name: HOP1
Reference locus (S288C): YIL072W
Gene biotype: protein_coding
Description: Meiosis-specific protein required for chromosome synapsis; displays Red1p dependent localization to the unsynapsed axial-lateral elements of the synaptonemal complex; required for chiasma formation; in vitro, displays the ability to promote intra- and intermolecular synapsis between double-stranded DNA molecules and to fold DNA into rigid protein-DNA filaments
Top 10 interactors (score): RED1 (0.999); MEK1 (0.997); DMC1 (0.974); PCH2 (0.973); SPO11 (0.959); REC8 (0.9); SPO22 (0.894); HOP2 (0.891); MND1 (0.889); ZIP1 (0.885); MSH4 (0.883); DOT1 (0.87); MSH5 (0.867); RAD51 (0.855); REC104 (0.847); ZIP2 (0.842); STE7 (0.837); YHR020W (0.836); SPO13 (0.813); NDT80 (0.789)
Homologues (species, bitscore): HORMAD2 (Homo sapiens, 74.3); Hormad1 (Mus musculus, 70.9); zte38 (Danio rerio, 75.5); hormad1 (Xenopus tropicalis, 75.1); ASY1 (Arabidopsis thaliana, 94.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:223271-225088:+ | gene-YIL072W_AKU4011 | rna-NM_001179422.3_AKU4011 | cds-NP_012193.3_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000164.1:85203-87020:+ | gene-YIL072W_BG1 | rna-NM_001179422.3_BG1 | cds-NP_012193.3_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:228686-230503:+ | gene-YIL072W_Bruggeman | rna-NM_001179422.3_Bruggeman | cds-NP_012193.3_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:218965-220782:+ | gene-YIL072W_CAT1 | rna-NM_001179422.3_CAT1 | cds-NP_012193.3_CAT1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:222842-224659:+ | gene-YIL072W_CBS1585 | rna-NM_001179422.3_CBS1585 | cds-NP_012193.3_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:218893-220710:+ | gene-YIL072W_CBS436 | rna-NM_001179422.3_CBS436 | cds-NP_012193.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:220219-222036:+ | gene-YIL072W_CBS6412 | rna-NM_001179422.3_CBS6412 | cds-NP_012193.3_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:214762-216579:+ | gene-YIL072W_CBS6413 | rna-NM_001179422.3_CBS6413 | cds-NP_012193.3_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:218306-220123:+ | gene-YIL072W_CENPK1137D | rna-NM_001179422.3_CENPK1137D | cds-NP_012193.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:207567-209384:+ | gene-YIL072W_EthanolRed | rna-NM_001179422.3_EthanolRed | cds-NP_012193.3_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:224475-226292:+ | gene-YIL072W_FaliES1 | rna-NM_001179422.3_FaliES1 | cds-NP_012193.3_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000025.1:3220-5037:- | gene-YIL072W_JAY291 | rna-NM_001179422.3_JAY291 | cds-NP_012193.3_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:226906-228723:+ | gene-YIL072W_MUCL30387 | rna-NM_001179422.3_MUCL30387 | cds-NP_012193.3_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:223515-225332:+ | gene-YIL072W_MUCL30388 | rna-NM_001179422.3_MUCL30388 | cds-NP_012193.3_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:223689-225506:+ | gene-YIL072W_MUCL39482 | rna-NM_001179422.3_MUCL39482 | cds-NP_012193.3_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:227053-228870:+ | gene-YIL072W_MUCL42920 | rna-NM_001179422.3_MUCL42920 | cds-NP_012193.3_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:226602-228419:+ | gene-YIL072W_NCIM3186 | rna-NM_001179422.3_NCIM3186 | cds-NP_012193.3_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:227966-229783:+ | gene-YIL072W_NCYC1407 | rna-NM_001179422.3_NCYC1407 | cds-NP_012193.3_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:221947-223764:+ | gene-YIL072W_PE2H3 | rna-NM_001179422.3_PE2H3 | cds-NP_012193.3_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:216664-218481:+ | gene-YIL072W_PE2H4 | rna-NM_001179422.3_PE2H4 | cds-NP_012193.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:226602-228419:+ | gene-YIL072W_S288C | rna-NM_001179422.3_S288C | cds-NP_012193.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000031.1:97415-99232:- | gene-YIL072W_SA1 | rna-NM_001179422.3_SA1 | cds-NP_012193.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:223139-224956:+ | gene-YIL072W_ThermosaccDry | rna-NM_001179422.3_ThermosaccDry | cds-NP_012193.3_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:220822-222639:+ | gene-YIL072W_VR1 | rna-NM_001179422.3_VR1 | cds-NP_012193.3_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:197401-199218:+ | gene-YIL072W_ZTW1 | rna-NM_001179422.3_ZTW1 | cds-NP_012193.3_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:221547-223364:+ | gene-YIL072W_Sparadoxus | rna-NM_001179422.3_Sparadoxus | cds-NP_012193.3_Sparadoxus | 88.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |