Gene name: HOM6
Reference locus (S288C): YJR139C
Gene biotype: protein_coding
Description: Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase); dimeric enzyme that catalyzes the third step in the common pathway for methionine and threonine biosynthesis; enzyme has nucleotide-binding, dimerization and catalytic regions
Top 10 interactors (score): THR1 (0.999); HOM2 (0.999); HOM3 (0.999); THR4 (0.997); MET2 (0.993); MET6 (0.954); STR2 (0.936); STR3 (0.934); CHA1 (0.933); CYS3 (0.921); CYS4 (0.916); BAT1 (0.882); BAT2 (0.875); TRP5 (0.853); YML082W (0.848); IRC7 (0.84); YLL058W (0.84); SAM4 (0.838); MHT1 (0.838); SAH1 (0.815)
Homologues (species, bitscore): AKHSDH1 (Arabidopsis thaliana, 268.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:660943-662022:- | gene-YJR139C_AKU4011 | rna-NM_001181797.3_AKU4011 | cds-NP_012673.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000076.1:11580-12659:+ | gene-YJR139C_BG1 | rna-NM_001181797.3_BG1 | cds-NP_012673.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:676675-677754:- | gene-YJR139C_Bruggeman | rna-NM_001181797.3_Bruggeman | cds-NP_012673.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:681310-682389:- | gene-YJR139C_CAT1 | rna-NM_001181797.3_CAT1 | cds-NP_012673.3_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:672987-674066:- | gene-YJR139C_CBS1585 | rna-NM_001181797.3_CBS1585 | cds-NP_012673.3_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:691857-692936:- | gene-YJR139C_CBS436 | rna-NM_001181797.3_CBS436 | cds-NP_012673.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:659762-660841:- | gene-YJR139C_CBS6412 | rna-NM_001181797.3_CBS6412 | cds-NP_012673.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:662421-663500:- | gene-YJR139C_CBS6413 | rna-NM_001181797.3_CBS6413 | cds-NP_012673.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:671805-672884:- | gene-YJR139C_CENPK1137D | rna-NM_001181797.3_CENPK1137D | cds-NP_012673.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:665364-666443:- | gene-YJR139C_EthanolRed | rna-NM_001181797.3_EthanolRed | cds-NP_012673.3_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:676827-677906:- | gene-YJR139C_FaliES1 | rna-NM_001181797.3_FaliES1 | cds-NP_012673.3_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000054.1:11253-12332:+ | gene-YJR139C_JAY291 | rna-NM_001181797.3_JAY291 | cds-NP_012673.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:675702-676781:- | gene-YJR139C_MUCL30387 | rna-NM_001181797.3_MUCL30387 | cds-NP_012673.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:673188-674267:- | gene-YJR139C_MUCL30388 | rna-NM_001181797.3_MUCL30388 | cds-NP_012673.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:666472-667551:- | gene-YJR139C_MUCL39482 | rna-NM_001181797.3_MUCL39482 | cds-NP_012673.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:671207-672286:- | gene-YJR139C_MUCL42920 | rna-NM_001181797.3_MUCL42920 | cds-NP_012673.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:689424-690503:- | gene-YJR139C_NCIM3186 | rna-NM_001181797.3_NCIM3186 | cds-NP_012673.3_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:664019-665098:- | gene-YJR139C_NCYC1407 | rna-NM_001181797.3_NCYC1407 | cds-NP_012673.3_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:682209-683288:- | gene-YJR139C_PE2H3 | rna-NM_001181797.3_PE2H3 | cds-NP_012673.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:675898-676977:- | gene-YJR139C_PE2H4 | rna-NM_001181797.3_PE2H4 | cds-NP_012673.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:689445-690524:- | gene-YJR139C_S288C | rna-NM_001181797.3_S288C | cds-NP_012673.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000069.1:11605-12684:+ | gene-YJR139C_SA1 | rna-NM_001181797.3_SA1 | cds-NP_012673.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:670758-671837:- | gene-YJR139C_ThermosaccDry | rna-NM_001181797.3_ThermosaccDry | cds-NP_012673.3_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:673129-674208:- | gene-YJR139C_VR1 | rna-NM_001181797.3_VR1 | cds-NP_012673.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:650107-651186:- | gene-YJR139C_ZTW1 | rna-NM_001181797.3_ZTW1 | cds-NP_012673.3_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:684411-685490:- | gene-YJR139C_Sparadoxus | rna-NM_001181797.3_Sparadoxus | cds-NP_012673.3_Sparadoxus | 93.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |