Gene name: HOM3
Reference locus (S288C): YER052C
Gene biotype: protein_coding
Description: Aspartokinase; Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis; Belongs to the aspartokinase family
Top 10 interactors (score): HOM6 (0.999); HOM2 (0.999); THR1 (0.999); THR4 (0.997); TRP5 (0.984); ASN1 (0.979); ASN2 (0.964); ARG1 (0.952); ILV1 (0.905); ADE8 (0.901); AAT1 (0.901); AAT2 (0.894); FPR1 (0.894); HXT13 (0.89); ARG5,6 (0.881); TRP3 (0.865); ARG4 (0.842); ADE12 (0.835); HIS1 (0.834); URA2 (0.818)
Homologues (species, bitscore): AK-LYS1 (Arabidopsis thaliana, 193.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:250170-251753:- | gene-YER052C_AKU4011 | rna-NM_001178943.1_AKU4011 | cds-NP_010972.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000011.1:174055-175638:+ | gene-YER052C_BG1 | rna-NM_001178943.1_BG1 | cds-NP_010972.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:258961-260544:- | gene-YER052C_Bruggeman | rna-NM_001178943.1_Bruggeman | cds-NP_010972.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:253114-254697:- | gene-YER052C_CAT1 | rna-NM_001178943.1_CAT1 | cds-NP_010972.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:250016-251599:- | gene-YER052C_CBS1585 | rna-NM_001178943.1_CBS1585 | cds-NP_010972.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:251930-253513:- | gene-YER052C_CBS436 | rna-NM_001178943.1_CBS436 | cds-NP_010972.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:249485-251068:- | gene-YER052C_CBS6412 | rna-NM_001178943.1_CBS6412 | cds-NP_010972.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:255510-257093:- | gene-YER052C_CBS6413 | rna-NM_001178943.1_CBS6413 | cds-NP_010972.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:254227-255810:- | gene-YER052C_CENPK1137D | rna-NM_001178943.1_CENPK1137D | cds-NP_010972.1_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:250496-252079:- | gene-YER052C_EthanolRed | rna-NM_001178943.1_EthanolRed | cds-NP_010972.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:250966-252549:- | gene-YER052C_FaliES1 | rna-NM_001178943.1_FaliES1 | cds-NP_010972.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000192.1:48722-50305:- | gene-YER052C_JAY291 | rna-NM_001178943.1_JAY291 | cds-NP_010972.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:254419-256002:- | gene-YER052C_MUCL30387 | rna-NM_001178943.1_MUCL30387 | cds-NP_010972.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:250588-252171:- | gene-YER052C_MUCL30388 | rna-NM_001178943.1_MUCL30388 | cds-NP_010972.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:249038-250621:- | gene-YER052C_MUCL39482 | rna-NM_001178943.1_MUCL39482 | cds-NP_010972.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:256102-257685:- | gene-YER052C_MUCL42920 | rna-NM_001178943.1_MUCL42920 | cds-NP_010972.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:256374-257957:- | gene-YER052C_NCIM3186 | rna-NM_001178943.1_NCIM3186 | cds-NP_010972.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:254120-255703:- | gene-YER052C_NCYC1407 | rna-NM_001178943.1_NCYC1407 | cds-NP_010972.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:264747-266330:- | gene-YER052C_PE2H3 | rna-NM_001178943.1_PE2H3 | cds-NP_010972.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:254688-256271:- | gene-YER052C_PE2H4 | rna-NM_001178943.1_PE2H4 | cds-NP_010972.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:256375-257958:- | gene-YER052C_S288C | rna-NM_001178943.1_S288C | cds-NP_010972.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000059.1:42836-44419:- | gene-YER052C_SA1 | rna-NM_001178943.1_SA1 | cds-NP_010972.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:251756-253339:- | gene-YER052C_ThermosaccDry | rna-NM_001178943.1_ThermosaccDry | cds-NP_010972.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:250824-252407:- | gene-YER052C_VR1 | rna-NM_001178943.1_VR1 | cds-NP_010972.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000009.1:248946-250529:- | gene-YER052C_ZTW1 | rna-NM_001178943.1_ZTW1 | cds-NP_010972.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:252793-254376:- | gene-YER052C_Sparadoxus | rna-NM_001178943.1_Sparadoxus | cds-NP_010972.1_Sparadoxus | 93.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |