HOM2 (YDR158W)


Gene profile

Gene name: HOM2
Reference locus (S288C): YDR158W
Gene biotype: protein_coding

Description: Aspartic beta semi-aldehyde dehydrogenase; catalyzes the second step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis; Belongs to the aspartate-semialdehyde dehydrogenase family

Top 10 interactors (score): HOM6 (0.999); HOM3 (0.999); THR1 (0.997); THR4 (0.997); ILV6 (0.944); ARO2 (0.919); ILV3 (0.917); ARO1 (0.908); ARG1 (0.888); TRP5 (0.884); MET2 (0.854); GLY1 (0.83); ILV5 (0.83); ARG5,6 (0.824); ILV1 (0.821); HIS4 (0.81); BAT1 (0.803); LEU4 (0.799); BAT2 (0.798); PGK1 (0.79)

Homologues (species, bitscore): AT1G14810 (Arabidopsis thaliana, 88.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:741678-742775:+ gene-YDR158W_AKU4011 rna-NM_001180465.3_AKU4011 cds-NP_010442.3_AKU4011 99.7 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:383979-385076:- gene-YDR158W_BG1 rna-NM_001180465.3_BG1 cds-NP_010442.3_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:773176-774273:+ gene-YDR158W_Bruggeman rna-NM_001180465.3_Bruggeman cds-NP_010442.3_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:760463-761560:+ gene-YDR158W_CAT1 rna-NM_001180465.3_CAT1 cds-NP_010442.3_CAT1 99.9 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:732046-733143:+ gene-YDR158W_CBS1585 rna-NM_001180465.3_CBS1585 cds-NP_010442.3_CBS1585 99.7 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:758216-759313:+ gene-YDR158W_CBS436 rna-NM_001180465.3_CBS436 cds-NP_010442.3_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:727528-728625:+ gene-YDR158W_CBS6412 rna-NM_001180465.3_CBS6412 cds-NP_010442.3_CBS6412 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:755944-757041:+ gene-YDR158W_CBS6413 rna-NM_001180465.3_CBS6413 cds-NP_010442.3_CBS6413 99.7 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:771045-772142:+ gene-YDR158W_CENPK1137D rna-NM_001180465.3_CENPK1137D cds-NP_010442.3_CENPK1137D 99.6 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:741505-742602:+ gene-YDR158W_EthanolRed rna-NM_001180465.3_EthanolRed cds-NP_010442.3_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:749717-750814:+ gene-YDR158W_FaliES1 rna-NM_001180465.3_FaliES1 cds-NP_010442.3_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000401.1:10632-11729:+ gene-YDR158W_JAY291 rna-NM_001180465.3_JAY291 cds-NP_010442.3_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:758147-759244:+ gene-YDR158W_MUCL30387 rna-NM_001180465.3_MUCL30387 cds-NP_010442.3_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:747064-748161:+ gene-YDR158W_MUCL30388 rna-NM_001180465.3_MUCL30388 cds-NP_010442.3_MUCL30388 99.6 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:733473-734570:+ gene-YDR158W_MUCL39482 rna-NM_001180465.3_MUCL39482 cds-NP_010442.3_MUCL39482 99.7 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:671298-672395:+ gene-YDR158W_MUCL42920 rna-NM_001180465.3_MUCL42920 cds-NP_010442.3_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:770280-771377:+ gene-YDR158W_NCIM3186 rna-NM_001180465.3_NCIM3186 cds-NP_010442.3_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:732877-733974:+ gene-YDR158W_NCYC1407 rna-NM_001180465.3_NCYC1407 cds-NP_010442.3_NCYC1407 99.7 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:752066-753163:+ gene-YDR158W_PE2H3 rna-NM_001180465.3_PE2H3 cds-NP_010442.3_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:751371-752468:+ gene-YDR158W_PE2H4 rna-NM_001180465.3_PE2H4 cds-NP_010442.3_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:770357-771454:+ gene-YDR158W_S288C rna-NM_001180465.3_S288C cds-NP_010442.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000009.1:117577-118674:+ gene-YDR158W_SA1 rna-NM_001180465.3_SA1 cds-NP_010442.3_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:747852-748949:+ gene-YDR158W_ThermosaccDry rna-NM_001180465.3_ThermosaccDry cds-NP_010442.3_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:762778-763875:+ gene-YDR158W_VR1 rna-NM_001180465.3_VR1 cds-NP_010442.3_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000007.1:10603-11699:+ gene-YDR158W_ZTW1 rna-NM_001180465.3_ZTW1 cds-NP_010442.3_ZTW1 99.6 99.9 Unannotated 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:754122-755219:+ gene-YDR158W_Sparadoxus rna-NM_001180465.3_Sparadoxus cds-NP_010442.3_Sparadoxus 91.8 100.0 Verified 1 1 1 False True False False False

Additional files