Gene name: HOG1
Reference locus (S288C): YLR113W
Gene biotype: protein_coding
Description: Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress
Top 10 interactors (score): PTP3 (0.999); SKO1 (0.999); HOT1 (0.999); PTP2 (0.999); PTP1 (0.999); PBS2 (0.999); SHO1 (0.998); PTC1 (0.997); SSK1 (0.996); STE7 (0.996); YPD1 (0.995); MSN2 (0.993); FPS1 (0.992); SLN1 (0.99); SMP1 (0.987); MSN4 (0.984); RCK2 (0.983); MIH1 (0.981); SIC1 (0.98); CRM1 (0.98)
Homologues (species, bitscore): MAPK14 (Homo sapiens, 374.8); Mapk14 (Mus musculus, 375.9); mapk14b (Danio rerio, 376.7); mapk11 (Xenopus tropicalis, 367.1); p38b (Drosophila melanogaster, 371.7); pmk-1 (Caenorhabditis elegans, 340.5); MPK6 (Arabidopsis thaliana, 348.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:354435-355742:+ | gene-YLR113W_AKU4011 | rna-NM_001182000.1_AKU4011 | cds-NP_013214.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:317881-319188:+ | gene-YLR113W_BG1 | rna-NM_001182000.1_BG1 | cds-NP_013214.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:363974-365281:+ | gene-YLR113W_Bruggeman | rna-NM_001182000.1_Bruggeman | cds-NP_013214.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:365488-366795:+ | gene-YLR113W_CAT1 | rna-NM_001182000.1_CAT1 | cds-NP_013214.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:361578-362885:+ | gene-YLR113W_CBS1585 | rna-NM_001182000.1_CBS1585 | cds-NP_013214.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:351826-353133:+ | gene-YLR113W_CBS436 | rna-NM_001182000.1_CBS436 | cds-NP_013214.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:359996-361303:+ | gene-YLR113W_CBS6412 | rna-NM_001182000.1_CBS6412 | cds-NP_013214.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:361843-363150:+ | gene-YLR113W_CBS6413 | rna-NM_001182000.1_CBS6413 | cds-NP_013214.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:356640-357947:+ | gene-YLR113W_CENPK1137D | rna-NM_001182000.1_CENPK1137D | cds-NP_013214.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:354000-355307:+ | gene-YLR113W_EthanolRed | rna-NM_001182000.1_EthanolRed | cds-NP_013214.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:353481-354788:+ | gene-YLR113W_FaliES1 | rna-NM_001182000.1_FaliES1 | cds-NP_013214.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000129.1:128428-129735:+ | gene-YLR113W_JAY291 | rna-NM_001182000.1_JAY291 | cds-NP_013214.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:361352-362659:+ | gene-YLR113W_MUCL30387 | rna-NM_001182000.1_MUCL30387 | cds-NP_013214.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:369016-370323:+ | gene-YLR113W_MUCL30388 | rna-NM_001182000.1_MUCL30388 | cds-NP_013214.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:362087-363394:+ | gene-YLR113W_MUCL39482 | rna-NM_001182000.1_MUCL39482 | cds-NP_013214.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:362212-363519:+ | gene-YLR113W_MUCL42920 | rna-NM_001182000.1_MUCL42920 | cds-NP_013214.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:371594-372901:+ | gene-YLR113W_NCIM3186 | rna-NM_001182000.1_NCIM3186 | cds-NP_013214.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:354360-355667:+ | gene-YLR113W_NCYC1407 | rna-NM_001182000.1_NCYC1407 | cds-NP_013214.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:359591-360898:+ | gene-YLR113W_PE2H3 | rna-NM_001182000.1_PE2H3 | cds-NP_013214.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:359332-360639:+ | gene-YLR113W_PE2H4 | rna-NM_001182000.1_PE2H4 | cds-NP_013214.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:371620-372927:+ | gene-YLR113W_S288C | rna-NM_001182000.1_S288C | cds-NP_013214.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000033.1:1163-2470:- | gene-YLR113W_SA1 | rna-NM_001182000.1_SA1 | cds-NP_013214.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:354440-355747:+ | gene-YLR113W_ThermosaccDry | rna-NM_001182000.1_ThermosaccDry | cds-NP_013214.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:367831-369138:+ | gene-YLR113W_VR1 | rna-NM_001182000.1_VR1 | cds-NP_013214.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:353140-354447:+ | gene-YLR113W_ZTW1 | rna-NM_001182000.1_ZTW1 | cds-NP_013214.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:361860-363167:+ | gene-YLR113W_Sparadoxus | rna-NM_001182000.1_Sparadoxus | cds-NP_013214.1_Sparadoxus | 92.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |