Gene name: HOF1
Reference locus (S288C): YMR032W
Gene biotype: protein_coding
Description: Cytokinesis protein 2; Protein that regulates actin cytoskeleton organization; required for cytokinesis, actin cable organization, and secretory vesicle trafficking; localized to bud neck; phosphorylated by Dbf2p; regulates actomyosin ring dynamics and septin localization; contains an SH3 domain; N terminus controls cell size and levels of actin cables, while C terminus controls actin cable organization via direct regulation of the formin Bnr1p
Top 10 interactors (score): INN1 (0.999); CYK3 (0.999); IQG1 (0.998); CHS2 (0.994); VRP1 (0.993); CDC14 (0.993); BNR1 (0.993); MYO1 (0.992); BNI1 (0.989); LAS17 (0.98); BZZ1 (0.977); MLC1 (0.963); MOB1 (0.956); SHO1 (0.955); DBF2 (0.952); RGD1 (0.941); LRG1 (0.937); CDC5 (0.936); RVS167 (0.932); APL3 (0.928)
Homologues (species, bitscore): GAS7 (Homo sapiens, 56.2); Gas7 (Mus musculus, 53.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:384896-386905:+ | gene-YMR032W_AKU4011 | rna-NM_001182529.1_AKU4011 | cds-NP_013746.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:155949-157958:- | gene-YMR032W_BG1 | rna-NM_001182529.1_BG1 | cds-NP_013746.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:324836-326845:+ | gene-YMR032W_Bruggeman | rna-NM_001182529.1_Bruggeman | cds-NP_013746.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:327351-329360:+ | gene-YMR032W_CAT1 | rna-NM_001182529.1_CAT1 | cds-NP_013746.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:317835-319844:+ | gene-YMR032W_CBS1585 | rna-NM_001182529.1_CBS1585 | cds-NP_013746.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:323387-325396:+ | gene-YMR032W_CBS436 | rna-NM_001182529.1_CBS436 | cds-NP_013746.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:431239-433248:+ | gene-YMR032W_CBS6412 | rna-NM_001182529.1_CBS6412 | cds-NP_013746.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:317093-319102:+ | gene-YMR032W_CBS6413 | rna-NM_001182529.1_CBS6413 | cds-NP_013746.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:330027-332036:+ | gene-YMR032W_CENPK1137D | rna-NM_001182529.1_CENPK1137D | cds-NP_013746.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:317669-319678:+ | gene-YMR032W_EthanolRed | rna-NM_001182529.1_EthanolRed | cds-NP_013746.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:320851-322860:+ | gene-YMR032W_FaliES1 | rna-NM_001182529.1_FaliES1 | cds-NP_013746.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000033.1:114080-116089:- | gene-YMR032W_JAY291 | rna-NM_001182529.1_JAY291 | cds-NP_013746.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:322795-324804:+ | gene-YMR032W_MUCL30387 | rna-NM_001182529.1_MUCL30387 | cds-NP_013746.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:327220-329229:+ | gene-YMR032W_MUCL30388 | rna-NM_001182529.1_MUCL30388 | cds-NP_013746.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:318120-320129:+ | gene-YMR032W_MUCL39482 | rna-NM_001182529.1_MUCL39482 | cds-NP_013746.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:323940-325949:+ | gene-YMR032W_MUCL42920 | rna-NM_001182529.1_MUCL42920 | cds-NP_013746.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:335252-337261:+ | gene-YMR032W_NCIM3186 | rna-NM_001182529.1_NCIM3186 | cds-NP_013746.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:318037-320046:+ | gene-YMR032W_NCYC1407 | rna-NM_001182529.1_NCYC1407 | cds-NP_013746.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:323983-325992:+ | gene-YMR032W_PE2H3 | rna-NM_001182529.1_PE2H3 | cds-NP_013746.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:330078-332087:+ | gene-YMR032W_PE2H4 | rna-NM_001182529.1_PE2H4 | cds-NP_013746.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:335298-337307:+ | gene-YMR032W_S288C | rna-NM_001182529.1_S288C | cds-NP_013746.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:200956-202965:- | gene-YMR032W_SA1 | rna-NM_001182529.1_SA1 | cds-NP_013746.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:317920-319929:+ | gene-YMR032W_ThermosaccDry | rna-NM_001182529.1_ThermosaccDry | cds-NP_013746.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:322623-324632:+ | gene-YMR032W_VR1 | rna-NM_001182529.1_VR1 | cds-NP_013746.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:296936-298945:+ | gene-YMR032W_ZTW1 | rna-NM_001182529.1_ZTW1 | cds-NP_013746.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:330868-332877:+ | gene-YMR032W_Sparadoxus | rna-NM_001182529.1_Sparadoxus | cds-NP_013746.1_Sparadoxus | 88.3 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |