Gene name: HO
Reference locus (S288C): YDL227C
Gene biotype: protein_coding
Description: Homothallic switching endonuclease; Site-specific endonuclease; required for gene conversion at the MAT locus (homothallic switching) through the generation of a ds DNA break; expression restricted to mother cells in late G1 as controlled by Swi4p-Swi6p, Swi5p, and Ash1p
Top 10 interactors (score): PUF4 (0.757); YDL228C (0.747); YOL118C (0.716); YDL242W (0.671); UFO1 (0.669); TOP2 (0.584); YLR123C (0.573); YML018C (0.568); POL30 (0.53); SET6 (0.528); YKL069W (0.525); FLO1 (0.487); PUF3 (0.463); RPN1 (0.463); DDI1 (0.463); MPT5 (0.461); HSC82 (0.454); YKR011C (0.454); SNF8 (0.454); YPR003C (0.451)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:29872-31524:- | gene-YDL227C_AKU4011 | rna-NM_001180287.1_AKU4011 | cds-NP_010054.1_AKU4011 | 93.2 | 93.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000077.1:35575-37227:+ | gene-YDL227C_BG1 | rna-NM_001180287.1_BG1 | cds-NP_010054.1_BG1 | 93.4 | 93.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:45446-47206:- | gene-YDL227C_Bruggeman | rna-NM_001180287.1_Bruggeman | cds-NP_010054.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:265243-267003:- | gene-YDL227C_CAT1 | rna-NM_001180287.1_CAT1 | cds-NP_010054.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:28748-30400:- | gene-YDL227C_CBS1585 | rna-NM_001180287.1_CBS1585 | cds-NP_010054.1_CBS1585 | 93.2 | 93.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:243520-245280:- | gene-YDL227C_CBS436 | rna-NM_001180287.1_CBS436 | cds-NP_010054.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:28859-30511:- | gene-YDL227C_CBS6412 | rna-NM_001180287.1_CBS6412 | cds-NP_010054.1_CBS6412 | 93.2 | 93.8 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:46383-48035:- | gene-YDL227C_CBS6413 | rna-NM_001180287.1_CBS6413 | cds-NP_010054.1_CBS6413 | 93.2 | 93.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:44938-46698:- | gene-YDL227C_CENPK1137D | rna-NM_001180287.1_CENPK1137D | cds-NP_010054.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:42313-43964:- | gene-YDL227C_EthanolRed | rna-NM_001180287.1_EthanolRed | cds-NP_010054.1_EthanolRed | 93.2 | 93.8 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:46640-48291:- | gene-YDL227C_FaliES1 | rna-NM_001180287.1_FaliES1 | cds-NP_010054.1_FaliES1 | 93.2 | 93.8 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000213.1:970-2622:- | gene-YDL227C_JAY291 | rna-NM_001180287.1_JAY291 | cds-NP_010054.1_JAY291 | 93.4 | 93.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:44388-46148:- | gene-YDL227C_MUCL30387 | rna-NM_001180287.1_MUCL30387 | cds-NP_010054.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:252206-253966:- | gene-YDL227C_MUCL30388 | rna-NM_001180287.1_MUCL30388 | cds-NP_010054.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:29592-31244:- | gene-YDL227C_MUCL39482 | rna-NM_001180287.1_MUCL39482 | cds-NP_010054.1_MUCL39482 | 93.2 | 93.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:45530-47290:- | gene-YDL227C_MUCL42920 | rna-NM_001180287.1_MUCL42920 | cds-NP_010054.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:46194-47954:- | gene-YDL227C_NCIM3186 | rna-NM_001180287.1_NCIM3186 | cds-NP_010054.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:29548-31200:- | gene-YDL227C_NCYC1407 | rna-NM_001180287.1_NCYC1407 | cds-NP_010054.1_NCYC1407 | 93.2 | 93.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:36583-38235:- | gene-YDL227C_PE2H3 | rna-NM_001180287.1_PE2H3 | cds-NP_010054.1_PE2H3 | 93.4 | 93.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:36593-38245:- | gene-YDL227C_PE2H4 | rna-NM_001180287.1_PE2H4 | cds-NP_010054.1_PE2H4 | 93.4 | 93.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:46271-48031:- | gene-YDL227C_S288C | rna-NM_001180287.1_S288C | cds-NP_010054.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000094.1:776-2428:- | gene-YDL227C_SA1 | rna-NM_001180287.1_SA1 | cds-NP_010054.1_SA1 | 93.4 | 93.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:46395-48046:- | gene-YDL227C_ThermosaccDry | rna-NM_001180287.1_ThermosaccDry | cds-NP_010054.1_ThermosaccDry | 93.2 | 93.8 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:46570-48222:- | gene-YDL227C_VR1 | rna-NM_001180287.1_VR1 | cds-NP_010054.1_VR1 | 93.2 | 93.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:45455-47215:- | gene-YDL227C_ZTW1 | rna-NM_001180287.1_ZTW1 | cds-NP_010054.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:48827-50587:- | gene-YDL227C_Sparadoxus | rna-NM_001180287.1_Sparadoxus | cds-NP_010054.1_Sparadoxus | 90.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |