Gene name: HNT3
Reference locus (S288C): YOR258W
Gene biotype: protein_coding
Description: Aprataxin-like protein; DNA 5' AMP hydrolase involved in DNA repair; member of the histidine triad (HIT) superfamily of nucleotide-binding proteins; homolog of Aprataxin, a Hint related protein that is mutated in individuals with ataxia with oculomotor apraxia; relative distribution to nuclear foci decreases upon DNA replication stress
Top 10 interactors (score): TDP1 (0.928); DNL4 (0.892); CDC9 (0.89); YKU70 (0.889); TPP1 (0.875); RAD27 (0.872); POL2 (0.853); APN2 (0.838); OGG1 (0.827); YKU80 (0.796); DSE3 (0.746); POL4 (0.709); HNT2 (0.686); CIR2 (0.686); NTG1 (0.664); HNT1 (0.661); COQ2 (0.654); NTG2 (0.651); COQ8 (0.607); TOP1 (0.604)
Homologues (species, bitscore): APTX (Homo sapiens, 68.9); Aptx (Mus musculus, 70.5); aptx (Danio rerio, 69.7); aptx (Xenopus tropicalis, 72.8); CG5316 (Drosophila melanogaster, 67.0); APTX (Arabidopsis thaliana, 75.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:802446-803099:+ | gene-YOR258W_AKU4011 | rna-NM_001183677.1_AKU4011 | cds-NP_014901.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:204479-205132:+ | gene-YOR258W_BG1 | rna-NM_001183677.1_BG1 | cds-NP_014901.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:787905-788558:+ | gene-YOR258W_Bruggeman | rna-NM_001183677.1_Bruggeman | cds-NP_014901.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:788557-789210:+ | gene-YOR258W_CAT1 | rna-NM_001183677.1_CAT1 | cds-NP_014901.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:785435-786088:+ | gene-YOR258W_CBS1585 | rna-NM_001183677.1_CBS1585 | cds-NP_014901.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:784123-784776:+ | gene-YOR258W_CBS436 | rna-NM_001183677.1_CBS436 | cds-NP_014901.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:782554-783207:+ | gene-YOR258W_CBS6412 | rna-NM_001183677.1_CBS6412 | cds-NP_014901.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:791195-791848:+ | gene-YOR258W_CBS6413 | rna-NM_001183677.1_CBS6413 | cds-NP_014901.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:811432-812085:+ | gene-YOR258W_CENPK1137D | rna-NM_001183677.1_CENPK1137D | cds-NP_014901.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:778562-779215:+ | gene-YOR258W_EthanolRed | rna-NM_001183677.1_EthanolRed | cds-NP_014901.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:783961-784614:+ | gene-YOR258W_FaliES1 | rna-NM_001183677.1_FaliES1 | cds-NP_014901.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000381.1:42220-42873:- | gene-YOR258W_JAY291 | rna-NM_001183677.1_JAY291 | cds-NP_014901.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:792187-792840:+ | gene-YOR258W_MUCL30387 | rna-NM_001183677.1_MUCL30387 | cds-NP_014901.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:799303-799956:+ | gene-YOR258W_MUCL30388 | rna-NM_001183677.1_MUCL30388 | cds-NP_014901.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:792766-793419:+ | gene-YOR258W_MUCL39482 | rna-NM_001183677.1_MUCL39482 | cds-NP_014901.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:802350-803003:+ | gene-YOR258W_MUCL42920 | rna-NM_001183677.1_MUCL42920 | cds-NP_014901.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:811560-812213:+ | gene-YOR258W_NCIM3186 | rna-NM_001183677.1_NCIM3186 | cds-NP_014901.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:792864-793517:+ | gene-YOR258W_NCYC1407 | rna-NM_001183677.1_NCYC1407 | cds-NP_014901.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:792161-792814:+ | gene-YOR258W_PE2H3 | rna-NM_001183677.1_PE2H3 | cds-NP_014901.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:802538-803191:+ | gene-YOR258W_PE2H4 | rna-NM_001183677.1_PE2H4 | cds-NP_014901.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:811671-812324:+ | gene-YOR258W_S288C | rna-NM_001183677.1_S288C | cds-NP_014901.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:221661-222314:+ | gene-YOR258W_SA1 | rna-NM_001183677.1_SA1 | cds-NP_014901.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:783144-783797:+ | gene-YOR258W_ThermosaccDry | rna-NM_001183677.1_ThermosaccDry | cds-NP_014901.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:846601-847254:+ | gene-YOR258W_VR1 | rna-NM_001183677.1_VR1 | cds-NP_014901.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:516063-516716:+ | gene-YOR258W_ZTW1 | rna-NM_001183677.1_ZTW1 | cds-NP_014901.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:788926-789582:+ | gene-YOR258W_Sparadoxus | rna-NM_001183677.1_Sparadoxus | cds-NP_014901.1_Sparadoxus | 85.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |