HNT2 (YDR305C)


Gene profile

Gene name: HNT2
Reference locus (S288C): YDR305C
Gene biotype: protein_coding

Description: Bis(5'-adenosyl)-triphosphatase; Dinucleoside triphosphate hydrolase; has similarity to the tumor suppressor FHIT and belongs to the histidine triad (HIT) superfamily of nucleotide-binding proteins

Top 10 interactors (score): MGE1 (0.967); RBK1 (0.963); SFB3 (0.962); ARH1 (0.927); APA2 (0.9); APA1 (0.9); DCS1 (0.847); DUR1,2 (0.845); ADE2 (0.839); ADE1 (0.839); ERG10 (0.823); DCS2 (0.819); YNK1 (0.714); HNT3 (0.686); DDP1 (0.675); TSA1 (0.658); MIS1 (0.652); ADE3 (0.652); NIT1 (0.651); YIL165C (0.651)

Homologues (species, bitscore): FHIT (Homo sapiens, 92.4); Fhit (Mus musculus, 89.7); fhit (Danio rerio, 98.6); fhit (Xenopus tropicalis, 98.2); NitFhit (Drosophila melanogaster, 90.9); nft-1 (Caenorhabditis elegans, 88.2); FHIT (Arabidopsis thaliana, 97.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:1024759-1025501:- gene-YDR305C_AKU4011 rna-NM_001180613.1_AKU4011 cds-NP_010591.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:106075-106817:+ gene-YDR305C_BG1 rna-NM_001180613.1_BG1 cds-NP_010591.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1052026-1052768:- gene-YDR305C_Bruggeman rna-NM_001180613.1_Bruggeman cds-NP_010591.1_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1039023-1039765:- gene-YDR305C_CAT1 rna-NM_001180613.1_CAT1 cds-NP_010591.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1019204-1019946:- gene-YDR305C_CBS1585 rna-NM_001180613.1_CBS1585 cds-NP_010591.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1037574-1038316:- gene-YDR305C_CBS436 rna-NM_001180613.1_CBS436 cds-NP_010591.1_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1015886-1016628:- gene-YDR305C_CBS6412 rna-NM_001180613.1_CBS6412 cds-NP_010591.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1037124-1037866:- gene-YDR305C_CBS6413 rna-NM_001180613.1_CBS6413 cds-NP_010591.1_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1071388-1072130:- gene-YDR305C_CENPK1137D rna-NM_001180613.1_CENPK1137D cds-NP_010591.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:1023114-1023856:- gene-YDR305C_EthanolRed rna-NM_001180613.1_EthanolRed cds-NP_010591.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1031516-1032258:- gene-YDR305C_FaliES1 rna-NM_001180613.1_FaliES1 cds-NP_010591.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000130.1:49308-50050:- gene-YDR305C_JAY291 rna-NM_001180613.1_JAY291 cds-NP_010591.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1037511-1038253:- gene-YDR305C_MUCL30387 rna-NM_001180613.1_MUCL30387 cds-NP_010591.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1024608-1025350:- gene-YDR305C_MUCL30388 rna-NM_001180613.1_MUCL30388 cds-NP_010591.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1011010-1011752:- gene-YDR305C_MUCL39482 rna-NM_001180613.1_MUCL39482 cds-NP_010591.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:950976-951718:- gene-YDR305C_MUCL42920 rna-NM_001180613.1_MUCL42920 cds-NP_010591.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1072669-1073411:- gene-YDR305C_NCIM3186 rna-NM_001180613.1_NCIM3186 cds-NP_010591.1_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1024303-1025045:- gene-YDR305C_NCYC1407 rna-NM_001180613.1_NCYC1407 cds-NP_010591.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1035281-1036023:- gene-YDR305C_PE2H3 rna-NM_001180613.1_PE2H3 cds-NP_010591.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1040866-1041608:- gene-YDR305C_PE2H4 rna-NM_001180613.1_PE2H4 cds-NP_010591.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1072746-1073488:- gene-YDR305C_S288C rna-NM_001180613.1_S288C cds-NP_010591.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000025.1:49481-50223:- gene-YDR305C_SA1 rna-NM_001180613.1_SA1 cds-NP_010591.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1035789-1036531:- gene-YDR305C_ThermosaccDry rna-NM_001180613.1_ThermosaccDry cds-NP_010591.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:1051700-1052442:- gene-YDR305C_VR1 rna-NM_001180613.1_VR1 cds-NP_010591.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:79904-80645:- gene-YDR305C_ZTW1 rna-NM_001180613.1_ZTW1 cds-NP_010591.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1031349-1032088:- gene-YDR305C_Sparadoxus rna-NM_001180613.1_Sparadoxus cds-NP_010591.1_Sparadoxus 87.9 100.0 Verified 1 1 1 False True False False False

Additional files