Gene name: HNT1
Reference locus (S288C): YDL125C
Gene biotype: protein_coding
Description: Hit family protein 1; Adenosine 5'-monophosphoramidase; interacts physically and genetically with Kin28p, a CDK and TFIIK subunit, and genetically with CAK1; member of histidine triad (HIT) superfamily of nucleotide-binding proteins; protein abundance increases in response to DNA replication stress; human homolog HINT1 can complement yeast hnt1 mutant
Top 10 interactors (score): GIM5 (0.896); KIN28 (0.88); TFB3 (0.853); ATP7 (0.741); DRE2 (0.671); FPR1 (0.67); HNT3 (0.661); SPC1 (0.649); RPS21B (0.629); ZAP1 (0.594); SNA4 (0.594); URA10 (0.585); ZRT3 (0.579); GUK1 (0.565); MSH5 (0.565); YNK1 (0.557); PRP5 (0.555); CCL1 (0.55); COX8 (0.548); IZH2 (0.526)
Homologues (species, bitscore): HINT1 (Homo sapiens, 60.1); Hint1 (Mus musculus, 58.5); hint1 (Danio rerio, 61.6); hint1 (Xenopus tropicalis, 54.3); CG2862 (Drosophila melanogaster, 62.4); hint-1 (Caenorhabditis elegans, 59.3); HINT3 (Arabidopsis thaliana, 86.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:223635-224222:- | gene-YDL125C_AKU4011 | rna-NM_001180184.1_AKU4011 | cds-NP_010158.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:325759-326346:+ | gene-YDL125C_BG1 | rna-NM_001180184.1_BG1 | cds-NP_010158.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:240788-241375:- | gene-YDL125C_Bruggeman | rna-NM_001180184.1_Bruggeman | cds-NP_010158.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:237790-238377:- | gene-YDL125C_CAT1 | rna-NM_001180184.1_CAT1 | cds-NP_010158.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:221900-222487:- | gene-YDL125C_CBS1585 | rna-NM_001180184.1_CBS1585 | cds-NP_010158.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:238553-239140:- | gene-YDL125C_CBS436 | rna-NM_001180184.1_CBS436 | cds-NP_010158.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:220325-220912:- | gene-YDL125C_CBS6412 | rna-NM_001180184.1_CBS6412 | cds-NP_010158.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 0 | False | False | True | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:240060-240647:- | gene-YDL125C_CBS6413 | rna-NM_001180184.1_CBS6413 | cds-NP_010158.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:237791-238378:- | gene-YDL125C_CENPK1137D | rna-NM_001180184.1_CENPK1137D | cds-NP_010158.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:234665-235252:- | gene-YDL125C_EthanolRed | rna-NM_001180184.1_EthanolRed | cds-NP_010158.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:240635-241222:- | gene-YDL125C_FaliES1 | rna-NM_001180184.1_FaliES1 | cds-NP_010158.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000010.1:10679-11266:- | gene-YDL125C_JAY291 | rna-NM_001180184.1_JAY291 | cds-NP_010158.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:238843-239430:- | gene-YDL125C_MUCL30387 | rna-NM_001180184.1_MUCL30387 | cds-NP_010158.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:229605-230192:- | gene-YDL125C_MUCL30388 | rna-NM_001180184.1_MUCL30388 | cds-NP_010158.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:223002-223589:- | gene-YDL125C_MUCL39482 | rna-NM_001180184.1_MUCL39482 | cds-NP_010158.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:144800-145387:- | gene-YDL125C_MUCL42920 | rna-NM_001180184.1_MUCL42920 | cds-NP_010158.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:238942-239529:- | gene-YDL125C_NCIM3186 | rna-NM_001180184.1_NCIM3186 | cds-NP_010158.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:223033-223620:- | gene-YDL125C_NCYC1407 | rna-NM_001180184.1_NCYC1407 | cds-NP_010158.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:229779-230366:- | gene-YDL125C_PE2H3 | rna-NM_001180184.1_PE2H3 | cds-NP_010158.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:229783-230370:- | gene-YDL125C_PE2H4 | rna-NM_001180184.1_PE2H4 | cds-NP_010158.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:239019-239606:- | gene-YDL125C_S288C | rna-NM_001180184.1_S288C | cds-NP_010158.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000010.1:195319-195906:+ | gene-YDL125C_SA1 | rna-NM_001180184.1_SA1 | cds-NP_010158.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:240146-240733:- | gene-YDL125C_ThermosaccDry | rna-NM_001180184.1_ThermosaccDry | cds-NP_010158.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:242253-242840:- | gene-YDL125C_VR1 | rna-NM_001180184.1_VR1 | cds-NP_010158.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:238076-238663:- | gene-YDL125C_ZTW1 | rna-NM_001180184.1_ZTW1 | cds-NP_010158.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:240218-240804:- | gene-YDL125C_Sparadoxus | rna-NM_001180184.1_Sparadoxus | cds-NP_010158.1_Sparadoxus | 90.8 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |