HMX1 (YLR205C)


Gene profile

Gene name: HMX1
Reference locus (S288C): YLR205C
Gene biotype: protein_coding

Description: Heme-binding protein HMX1; ER localized heme oxygenase; involved in heme degradation during iron starvation and in the oxidative stress response; expression is regulated by AFT1 and oxidative stress; relocates to the perinuclear region in the presence of oxidants

Top 10 interactors (score): HEM13 (0.901); CTS1 (0.885); CIS3 (0.885); HEM15 (0.882); GSH1 (0.826); HEM2 (0.762); HEM14 (0.76); CTT1 (0.756); HEM12 (0.755); HEM3 (0.73); FRE1 (0.723); GCN4 (0.719); HEM4 (0.705); YME1 (0.686); FET3 (0.68); SOD1 (0.679); FIT1 (0.673); AFT1 (0.669); GPX1 (0.664); CTA1 (0.649)

Homologues (species, bitscore): HMOX1 (Homo sapiens, 53.9); hmox2b (Danio rerio, 64.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:506857-507813:- gene-YLR205C_AKU4011 rna-NM_001182092.1_AKU4011 cds-NP_013306.2_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000177.1:64120-65076:- gene-YLR205C_BG1 rna-NM_001182092.1_BG1 cds-NP_013306.2_BG1 98.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:547110-548066:- gene-YLR205C_Bruggeman rna-NM_001182092.1_Bruggeman cds-NP_013306.2_Bruggeman 99.1 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:546688-547644:- gene-YLR205C_CAT1 rna-NM_001182092.1_CAT1 cds-NP_013306.2_CAT1 99.0 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:542354-543310:- gene-YLR205C_CBS1585 rna-NM_001182092.1_CBS1585 cds-NP_013306.2_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:532484-533440:- gene-YLR205C_CBS436 rna-NM_001182092.1_CBS436 cds-NP_013306.2_CBS436 99.0 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:510911-511867:- gene-YLR205C_CBS6412 rna-NM_001182092.1_CBS6412 cds-NP_013306.2_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:542646-543602:- gene-YLR205C_CBS6413 rna-NM_001182092.1_CBS6413 cds-NP_013306.2_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:537369-538322:- gene-YLR205C_CENPK1137D rna-NM_001182092.1_CENPK1137D cds-NP_013306.2_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:506383-507339:- gene-YLR205C_EthanolRed rna-NM_001182092.1_EthanolRed cds-NP_013306.2_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:535310-536266:- gene-YLR205C_FaliES1 rna-NM_001182092.1_FaliES1 cds-NP_013306.2_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000004.1:62197-63153:- gene-YLR205C_JAY291 rna-NM_001182092.1_JAY291 cds-NP_013306.2_JAY291 99.0 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:547129-548085:- gene-YLR205C_MUCL30387 rna-NM_001182092.1_MUCL30387 cds-NP_013306.2_MUCL30387 99.1 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:552063-553019:- gene-YLR205C_MUCL30388 rna-NM_001182092.1_MUCL30388 cds-NP_013306.2_MUCL30388 99.1 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:543335-544291:- gene-YLR205C_MUCL39482 rna-NM_001182092.1_MUCL39482 cds-NP_013306.2_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:543833-544789:- gene-YLR205C_MUCL42920 rna-NM_001182092.1_MUCL42920 cds-NP_013306.2_MUCL42920 99.1 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:552698-553651:- gene-YLR205C_NCIM3186 rna-NM_001182092.1_NCIM3186 cds-NP_013306.2_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:535766-536722:- gene-YLR205C_NCYC1407 rna-NM_001182092.1_NCYC1407 cds-NP_013306.2_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:539987-540943:- gene-YLR205C_PE2H3 rna-NM_001182092.1_PE2H3 cds-NP_013306.2_PE2H3 99.0 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:539731-540687:- gene-YLR205C_PE2H4 rna-NM_001182092.1_PE2H4 cds-NP_013306.2_PE2H4 99.0 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:552724-553677:- gene-YLR205C_S288C rna-NM_001182092.1_S288C cds-NP_013306.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000042.1:62256-63212:- gene-YLR205C_SA1 rna-NM_001182092.1_SA1 cds-NP_013306.2_SA1 98.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:537813-538769:- gene-YLR205C_ThermosaccDry rna-NM_001182092.1_ThermosaccDry cds-NP_013306.2_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:549096-550052:- gene-YLR205C_VR1 rna-NM_001182092.1_VR1 cds-NP_013306.2_VR1 98.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000024.1:62099-63055:- gene-YLR205C_ZTW1 rna-NM_001182092.1_ZTW1 cds-NP_013306.2_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:523879-524835:- gene-YLR205C_Sparadoxus rna-NM_001182092.1_Sparadoxus cds-NP_013306.2_Sparadoxus 90.9 100.0 Verified 1 1 1 False True False False False

Additional files