HMT1 (YBR034C)


Gene profile

Gene name: HMT1
Reference locus (S288C): YBR034C
Gene biotype: protein_coding

Description: Protein-arginine omega-n methyltransferase hmt1; Protein arginine N-methyltransferase 1; Nuclear SAM-dependent mono- and asymmetric methyltransferase; modifies hnRNPs, including Npl3p and Hrp1p, affecting their activity and nuclear export; methylates U1 snRNP protein Snp1p, ribosomal protein Rps2p, and histones H3 and H4; interacts genetically with genes encoding components of Rpd3(L) and this interaction is important for Rpd3 recruitment to the subtelomeric region

Top 10 interactors (score): NOP1 (0.997); RPS2 (0.996); RMT2 (0.994); NSR1 (0.99); HSL7 (0.989); NPL3 (0.988); PUF6 (0.986); YTM1 (0.982); BRX1 (0.978); ENP1 (0.977); RPF2 (0.974); DBP2 (0.971); GAR1 (0.971); NHP2 (0.968); HTA1 (0.967); HTA2 (0.965); RPB7 (0.962); PWP2 (0.961); UTP5 (0.959); ERB1 (0.956)

Homologues (species, bitscore): PRMT1 (Homo sapiens, 334.3); Prmt1 (Mus musculus, 332.0); prmt1 (Danio rerio, 334.7); prmt1 (Xenopus tropicalis, 334.3); Art1 (Drosophila melanogaster, 338.6); prmt-1 (Caenorhabditis elegans, 322.4); PRMT11 (Arabidopsis thaliana, 355.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:287362-288408:- gene-YBR034C_AKU4011 rna-NM_001178382.1_AKU4011 cds-NP_009590.1_AKU4011 99.9 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000179.1:277501-278547:- gene-YBR034C_BG1 rna-NM_001178382.1_BG1 cds-NP_009590.1_BG1 99.9 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:288089-289135:- gene-YBR034C_Bruggeman rna-NM_001178382.1_Bruggeman cds-NP_009590.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:291779-292825:- gene-YBR034C_CAT1 rna-NM_001178382.1_CAT1 cds-NP_009590.1_CAT1 99.9 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:279658-280704:- gene-YBR034C_CBS1585 rna-NM_001178382.1_CBS1585 cds-NP_009590.1_CBS1585 99.9 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:287665-288711:- gene-YBR034C_CBS436 rna-NM_001178382.1_CBS436 cds-NP_009590.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:377541-378587:- gene-YBR034C_CBS6412 rna-NM_001178382.1_CBS6412 cds-NP_009590.1_CBS6412 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:284774-285820:- gene-YBR034C_CBS6413 rna-NM_001178382.1_CBS6413 cds-NP_009590.1_CBS6413 99.9 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:298698-299744:- gene-YBR034C_CENPK1137D rna-NM_001178382.1_CENPK1137D cds-NP_009590.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:414139-415185:- gene-YBR034C_EthanolRed rna-NM_001178382.1_EthanolRed cds-NP_009590.1_EthanolRed 99.9 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:302989-304035:- gene-YBR034C_FaliES1 rna-NM_001178382.1_FaliES1 cds-NP_009590.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000441.1:27688-28734:+ gene-YBR034C_JAY291 rna-NM_001178382.1_JAY291 cds-NP_009590.1_JAY291 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:289691-290737:- gene-YBR034C_MUCL30387 rna-NM_001178382.1_MUCL30387 cds-NP_009590.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:289494-290540:- gene-YBR034C_MUCL30388 rna-NM_001178382.1_MUCL30388 cds-NP_009590.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:279646-280692:- gene-YBR034C_MUCL39482 rna-NM_001178382.1_MUCL39482 cds-NP_009590.1_MUCL39482 99.9 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:286840-287886:- gene-YBR034C_MUCL42920 rna-NM_001178382.1_MUCL42920 cds-NP_009590.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:304727-305773:- gene-YBR034C_NCIM3186 rna-NM_001178382.1_NCIM3186 cds-NP_009590.1_NCIM3186 99.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:280559-281605:- gene-YBR034C_NCYC1407 rna-NM_001178382.1_NCYC1407 cds-NP_009590.1_NCYC1407 99.9 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:292729-293775:- gene-YBR034C_PE2H3 rna-NM_001178382.1_PE2H3 cds-NP_009590.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:290405-291451:- gene-YBR034C_PE2H4 rna-NM_001178382.1_PE2H4 cds-NP_009590.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:304930-305976:- gene-YBR034C_S288C rna-NM_001178382.1_S288C cds-NP_009590.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000017.1:171571-172617:+ gene-YBR034C_SA1 rna-NM_001178382.1_SA1 cds-NP_009590.1_SA1 99.9 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:302429-303475:- gene-YBR034C_ThermosaccDry rna-NM_001178382.1_ThermosaccDry cds-NP_009590.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:284082-285128:- gene-YBR034C_VR1 rna-NM_001178382.1_VR1 cds-NP_009590.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:278155-279201:- gene-YBR034C_ZTW1 rna-NM_001178382.1_ZTW1 cds-NP_009590.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:314383-315429:- gene-YBR034C_Sparadoxus rna-NM_001178382.1_Sparadoxus cds-NP_009590.1_Sparadoxus 92.1 100.0 Verified 1 1 1 False True False False False

Additional files