HMF1 (YER057C)


Gene profile

Gene name: HMF1
Reference locus (S288C): YER057C
Gene biotype: protein_coding

Description: Protein HMF1; Member of the p14.5 protein family; functionally complements Mmf1p function when targeted to mitochondria; heat shock inducible; high-dosage growth inhibitor; forms a homotrimer in vitro; HMF1 has a paralog, MMF1, that arose from the whole genome duplication; Belongs to the RutC family

Top 10 interactors (score): DPH6 (0.919); DPH5 (0.825); RRT2 (0.81); DPH1 (0.778); KTI11 (0.741); MCX1 (0.733); DPH2 (0.709); MRX14 (0.705); MRX3 (0.696); MRPL38 (0.696); TRP4 (0.686); MRPL40 (0.676); QCR10 (0.671); ARO7 (0.671); LIH1 (0.659); YMR31 (0.652); PEP4 (0.651); HSP33 (0.638); JJJ3 (0.624); REX2 (0.613)

Homologues (species, bitscore): HRSP12 (Homo sapiens, 99.4); Hrsp12 (Mus musculus, 100.1); hrsp12 (Danio rerio, 83.6); UK114 (Drosophila melanogaster, 87.0); C23G10.2 (Caenorhabditis elegans, 87.4); AT3G20390 (Arabidopsis thaliana, 110.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:264535-264924:- gene-YER057C_AKU4011 rna-NM_001178948.3_AKU4011 cds-NP_010978.3_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000011.1:160854-161243:+ gene-YER057C_BG1 rna-NM_001178948.3_BG1 cds-NP_010978.3_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:273845-274234:- gene-YER057C_Bruggeman rna-NM_001178948.3_Bruggeman cds-NP_010978.3_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:267487-267876:- gene-YER057C_CAT1 rna-NM_001178948.3_CAT1 cds-NP_010978.3_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:264391-264780:- gene-YER057C_CBS1585 rna-NM_001178948.3_CBS1585 cds-NP_010978.3_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:266298-266687:- gene-YER057C_CBS436 rna-NM_001178948.3_CBS436 cds-NP_010978.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:263861-264250:- gene-YER057C_CBS6412 rna-NM_001178948.3_CBS6412 cds-NP_010978.3_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:269867-270256:- gene-YER057C_CBS6413 rna-NM_001178948.3_CBS6413 cds-NP_010978.3_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:268596-268985:- gene-YER057C_CENPK1137D rna-NM_001178948.3_CENPK1137D cds-NP_010978.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:264875-265264:- gene-YER057C_EthanolRed rna-NM_001178948.3_EthanolRed cds-NP_010978.3_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:265328-265717:- gene-YER057C_FaliES1 rna-NM_001178948.3_FaliES1 cds-NP_010978.3_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000382.1:6783-7172:+ gene-YER057C_JAY291 rna-NM_001178948.3_JAY291 cds-NP_010978.3_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:269281-269670:- gene-YER057C_MUCL30387 rna-NM_001178948.3_MUCL30387 cds-NP_010978.3_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:264959-265348:- gene-YER057C_MUCL30388 rna-NM_001178948.3_MUCL30388 cds-NP_010978.3_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:263426-263815:- gene-YER057C_MUCL39482 rna-NM_001178948.3_MUCL39482 cds-NP_010978.3_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:270487-270876:- gene-YER057C_MUCL42920 rna-NM_001178948.3_MUCL42920 cds-NP_010978.3_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:270736-271125:- gene-YER057C_NCIM3186 rna-NM_001178948.3_NCIM3186 cds-NP_010978.3_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:268489-268878:- gene-YER057C_NCYC1407 rna-NM_001178948.3_NCYC1407 cds-NP_010978.3_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:279139-279528:- gene-YER057C_PE2H3 rna-NM_001178948.3_PE2H3 cds-NP_010978.3_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:269080-269469:- gene-YER057C_PE2H4 rna-NM_001178948.3_PE2H4 cds-NP_010978.3_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:270737-271126:- gene-YER057C_S288C rna-NM_001178948.3_S288C cds-NP_010978.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000059.1:57259-57648:- gene-YER057C_SA1 rna-NM_001178948.3_SA1 cds-NP_010978.3_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:266124-266513:- gene-YER057C_ThermosaccDry rna-NM_001178948.3_ThermosaccDry cds-NP_010978.3_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:265822-266211:- gene-YER057C_VR1 rna-NM_001178948.3_VR1 cds-NP_010978.3_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:263306-263695:- gene-YER057C_ZTW1 rna-NM_001178948.3_ZTW1 cds-NP_010978.3_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:267182-267571:- gene-YER057C_Sparadoxus rna-NM_001178948.3_Sparadoxus cds-NP_010978.3_Sparadoxus 91.2 100.0 Verified 1 1 1 False True False False False

Additional files