HLR1 (YDR528W)


Gene profile

Gene name: HLR1
Reference locus (S288C): YDR528W
Gene biotype: protein_coding

Description: Protein involved in regulation of cell wall composition and integrity; also involved in cell wall response to osmotic stress; overproduction suppresses a lysis sensitive PKC mutation; HLR1 has a paralog, LRE1, that arose from the whole genome duplication

Top 10 interactors (score): EMW1 (0.75); DOP1 (0.696); FCY21 (0.65); SPS2 (0.619); KEG1 (0.596); TDA1 (0.596); FIT1 (0.583); YHR213W (0.574); PLM2 (0.567); PLB3 (0.554); KTR6 (0.526); SFK1 (0.497); YLR278C (0.487); CBK1 (0.466); TIR3 (0.454); KIC1 (0.453); KCC4 (0.451); DAN1 (0.45); FMP48 (0.402)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:1434622-1435893:+ gene-YDR528W_AKU4011 rna-NM_001180836.3_AKU4011 cds-NP_010817.3_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000073.1:76241-77512:+ gene-YDR528W_BG1 rna-NM_001180836.3_BG1 cds-NP_010817.3_BG1 99.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1465913-1467184:+ gene-YDR528W_Bruggeman rna-NM_001180836.3_Bruggeman cds-NP_010817.3_Bruggeman 99.3 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1443081-1444352:+ gene-YDR528W_CAT1 rna-NM_001180836.3_CAT1 cds-NP_010817.3_CAT1 99.2 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1429350-1430621:+ gene-YDR528W_CBS1585 rna-NM_001180836.3_CBS1585 cds-NP_010817.3_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1448549-1449820:+ gene-YDR528W_CBS436 rna-NM_001180836.3_CBS436 cds-NP_010817.3_CBS436 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1424514-1425785:+ gene-YDR528W_CBS6412 rna-NM_001180836.3_CBS6412 cds-NP_010817.3_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1448010-1449281:+ gene-YDR528W_CBS6413 rna-NM_001180836.3_CBS6413 cds-NP_010817.3_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1493263-1494534:+ gene-YDR528W_CENPK1137D rna-NM_001180836.3_CENPK1137D cds-NP_010817.3_CENPK1137D 99.6 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:1437881-1439152:+ gene-YDR528W_EthanolRed rna-NM_001180836.3_EthanolRed cds-NP_010817.3_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1441433-1442704:+ gene-YDR528W_FaliES1 rna-NM_001180836.3_FaliES1 cds-NP_010817.3_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000026.1:139773-141044:+ gene-YDR528W_JAY291 rna-NM_001180836.3_JAY291 cds-NP_010817.3_JAY291 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1449002-1450273:+ gene-YDR528W_MUCL30387 rna-NM_001180836.3_MUCL30387 cds-NP_010817.3_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1430450-1431721:+ gene-YDR528W_MUCL30388 rna-NM_001180836.3_MUCL30388 cds-NP_010817.3_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1420847-1422118:+ gene-YDR528W_MUCL39482 rna-NM_001180836.3_MUCL39482 cds-NP_010817.3_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:1363476-1364747:+ gene-YDR528W_MUCL42920 rna-NM_001180836.3_MUCL42920 cds-NP_010817.3_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1494509-1495780:+ gene-YDR528W_NCIM3186 rna-NM_001180836.3_NCIM3186 cds-NP_010817.3_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1434140-1435411:+ gene-YDR528W_NCYC1407 rna-NM_001180836.3_NCYC1407 cds-NP_010817.3_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1445040-1446311:+ gene-YDR528W_PE2H3 rna-NM_001180836.3_PE2H3 cds-NP_010817.3_PE2H3 99.2 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1450508-1451779:+ gene-YDR528W_PE2H4 rna-NM_001180836.3_PE2H4 cds-NP_010817.3_PE2H4 99.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1494586-1495857:+ gene-YDR528W_S288C rna-NM_001180836.3_S288C cds-NP_010817.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000004.1:121258-122529:- gene-YDR528W_SA1 rna-NM_001180836.3_SA1 cds-NP_010817.3_SA1 99.2 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1445655-1446926:+ gene-YDR528W_ThermosaccDry rna-NM_001180836.3_ThermosaccDry cds-NP_010817.3_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:1461430-1462701:+ gene-YDR528W_VR1 rna-NM_001180836.3_VR1 cds-NP_010817.3_VR1 99.2 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:488306-489577:+ gene-YDR528W_ZTW1 rna-NM_001180836.3_ZTW1 cds-NP_010817.3_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1454613-1455878:+ gene-YDR528W_Sparadoxus rna-NM_001180836.3_Sparadoxus cds-NP_010817.3_Sparadoxus 88.2 99.5 Verified 1 1 1 False True False False False

Additional files