HIS7 (YBR248C)


Gene profile

Gene name: HIS7
Reference locus (S288C): YBR248C
Gene biotype: protein_coding

Description: Imidazole glycerol phosphate synthase; glutamine amidotransferase:cyclase that catalyzes the fifth step of histidine biosynthesis and also produces 5-aminoimidazole-4-carboxamide ribotide (AICAR), a purine precursor; In the C-terminal section; belongs to the HisA/HisF family

Top 10 interactors (score): HIS4 (0.999); HIS6 (0.999); TRP3 (0.996); HIS3 (0.996); HIS5 (0.989); GUA1 (0.984); HIS1 (0.979); ADE5,7 (0.976); TRP5 (0.974); TRP1 (0.956); URA3 (0.914); TRP2 (0.907); ADE16 (0.904); ADE17 (0.904); ADE6 (0.881); LYS2 (0.881); BAS1 (0.85); ADE13 (0.849); LEU2 (0.84); ARG5,6 (0.834)

Homologues (species, bitscore): AT-HF (Arabidopsis thaliana, 533.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:699107-700765:- gene-YBR248C_AKU4011 rna-NM_001178596.3_AKU4011 cds-NP_009807.3_AKU4011 99.6 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000066.1:70112-71770:- gene-YBR248C_BG1 rna-NM_001178596.3_BG1 cds-NP_009807.3_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:700259-701917:- gene-YBR248C_Bruggeman rna-NM_001178596.3_Bruggeman cds-NP_009807.3_Bruggeman 99.9 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:703750-705408:- gene-YBR248C_CAT1 rna-NM_001178596.3_CAT1 cds-NP_009807.3_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:690673-692331:- gene-YBR248C_CBS1585 rna-NM_001178596.3_CBS1585 cds-NP_009807.3_CBS1585 99.6 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:697103-698761:- gene-YBR248C_CBS436 rna-NM_001178596.3_CBS436 cds-NP_009807.3_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:785278-786936:- gene-YBR248C_CBS6412 rna-NM_001178596.3_CBS6412 cds-NP_009807.3_CBS6412 99.6 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:696721-698379:- gene-YBR248C_CBS6413 rna-NM_001178596.3_CBS6413 cds-NP_009807.3_CBS6413 99.7 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:708717-710375:- gene-YBR248C_CENPK1137D rna-NM_001178596.3_CENPK1137D cds-NP_009807.3_CENPK1137D 99.9 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:822129-823787:- gene-YBR248C_EthanolRed rna-NM_001178596.3_EthanolRed cds-NP_009807.3_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:715476-717134:- gene-YBR248C_FaliES1 rna-NM_001178596.3_FaliES1 cds-NP_009807.3_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000067.1:86931-88589:+ gene-YBR248C_JAY291 rna-NM_001178596.3_JAY291 cds-NP_009807.3_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:702302-703960:- gene-YBR248C_MUCL30387 rna-NM_001178596.3_MUCL30387 cds-NP_009807.3_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:719385-721043:- gene-YBR248C_MUCL30388 rna-NM_001178596.3_MUCL30388 cds-NP_009807.3_MUCL30388 99.9 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:688980-690638:- gene-YBR248C_MUCL39482 rna-NM_001178596.3_MUCL39482 cds-NP_009807.3_MUCL39482 99.6 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:698837-700495:- gene-YBR248C_MUCL42920 rna-NM_001178596.3_MUCL42920 cds-NP_009807.3_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:714604-716262:- gene-YBR248C_NCIM3186 rna-NM_001178596.3_NCIM3186 cds-NP_009807.3_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:690869-692527:- gene-YBR248C_NCYC1407 rna-NM_001178596.3_NCYC1407 cds-NP_009807.3_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:713974-715632:- gene-YBR248C_PE2H3 rna-NM_001178596.3_PE2H3 cds-NP_009807.3_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:711650-713308:- gene-YBR248C_PE2H4 rna-NM_001178596.3_PE2H4 cds-NP_009807.3_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:714807-716465:- gene-YBR248C_S288C rna-NM_001178596.3_S288C cds-NP_009807.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000019.1:69935-71593:- gene-YBR248C_SA1 rna-NM_001178596.3_SA1 cds-NP_009807.3_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:714468-716126:- gene-YBR248C_ThermosaccDry rna-NM_001178596.3_ThermosaccDry cds-NP_009807.3_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:694682-696340:- gene-YBR248C_VR1 rna-NM_001178596.3_VR1 cds-NP_009807.3_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:687319-688977:- gene-YBR248C_ZTW1 rna-NM_001178596.3_ZTW1 cds-NP_009807.3_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:731281-732939:- gene-YBR248C_Sparadoxus rna-NM_001178596.3_Sparadoxus cds-NP_009807.3_Sparadoxus 90.8 99.9 Verified 1 1 1 False True False False False

Additional files