Gene name: HIS5
Reference locus (S288C): YIL116W
Gene biotype: protein_coding
Description: Histidinol-phosphate aminotransferase; catalyzes the seventh step in histidine biosynthesis; responsive to general control of amino acid biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts
Top 10 interactors (score): HIS3 (0.999); HIS4 (0.999); HIS7 (0.989); HIS6 (0.983); HIS1 (0.978); HIS2 (0.972); PHA2 (0.96); TYR1 (0.959); TRP3 (0.942); ARG4 (0.915); ARO10 (0.9); AAT2 (0.9); TRP5 (0.899); TRP1 (0.861); URA3 (0.857); ARG1 (0.85); AAT1 (0.848); GCN4 (0.841); ARO8 (0.825); ARG5,6 (0.818)
Homologues (species, bitscore): TAT (Homo sapiens, 50.1); Tat (Mus musculus, 51.2); tat (Danio rerio, 51.6); tatn-1 (Caenorhabditis elegans, 55.5); HISN6B (Arabidopsis thaliana, 142.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:144090-145247:+ | gene-YIL116W_AKU4011 | rna-NM_001179464.1_AKU4011 | cds-NP_012150.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000164.1:7010-8167:+ | gene-YIL116W_BG1 | rna-NM_001179464.1_BG1 | cds-NP_012150.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:148502-149659:+ | gene-YIL116W_Bruggeman | rna-NM_001179464.1_Bruggeman | cds-NP_012150.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:141015-142172:+ | gene-YIL116W_CAT1 | rna-NM_001179464.1_CAT1 | cds-NP_012150.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:144347-145504:+ | gene-YIL116W_CBS1585 | rna-NM_001179464.1_CBS1585 | cds-NP_012150.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:135516-136673:+ | gene-YIL116W_CBS436 | rna-NM_001179464.1_CBS436 | cds-NP_012150.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:141821-142978:+ | gene-YIL116W_CBS6412 | rna-NM_001179464.1_CBS6412 | cds-NP_012150.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:135553-136710:+ | gene-YIL116W_CBS6413 | rna-NM_001179464.1_CBS6413 | cds-NP_012150.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:134623-135780:+ | gene-YIL116W_CENPK1137D | rna-NM_001179464.1_CENPK1137D | cds-NP_012150.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:129436-130593:+ | gene-YIL116W_EthanolRed | rna-NM_001179464.1_EthanolRed | cds-NP_012150.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:145487-146644:+ | gene-YIL116W_FaliES1 | rna-NM_001179464.1_FaliES1 | cds-NP_012150.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000383.1:2861-4018:- | gene-YIL116W_JAY291 | rna-NM_001179464.1_JAY291 | cds-NP_012150.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:145821-146978:+ | gene-YIL116W_MUCL30387 | rna-NM_001179464.1_MUCL30387 | cds-NP_012150.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:144327-145484:+ | gene-YIL116W_MUCL30388 | rna-NM_001179464.1_MUCL30388 | cds-NP_012150.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:145290-146447:+ | gene-YIL116W_MUCL39482 | rna-NM_001179464.1_MUCL39482 | cds-NP_012150.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:148782-149939:+ | gene-YIL116W_MUCL42920 | rna-NM_001179464.1_MUCL42920 | cds-NP_012150.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:142928-144085:+ | gene-YIL116W_NCIM3186 | rna-NM_001179464.1_NCIM3186 | cds-NP_012150.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:149334-150491:+ | gene-YIL116W_NCYC1407 | rna-NM_001179464.1_NCYC1407 | cds-NP_012150.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:143824-144981:+ | gene-YIL116W_PE2H3 | rna-NM_001179464.1_PE2H3 | cds-NP_012150.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:137952-139109:+ | gene-YIL116W_PE2H4 | rna-NM_001179464.1_PE2H4 | cds-NP_012150.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:142928-144085:+ | gene-YIL116W_S288C | rna-NM_001179464.1_S288C | cds-NP_012150.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000058.1:39339-40496:- | gene-YIL116W_SA1 | rna-NM_001179464.1_SA1 | cds-NP_012150.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:144144-145301:+ | gene-YIL116W_ThermosaccDry | rna-NM_001179464.1_ThermosaccDry | cds-NP_012150.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:141132-142289:+ | gene-YIL116W_VR1 | rna-NM_001179464.1_VR1 | cds-NP_012150.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:119011-120168:+ | gene-YIL116W_ZTW1 | rna-NM_001179464.1_ZTW1 | cds-NP_012150.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:136846-138003:+ | gene-YIL116W_Sparadoxus | rna-NM_001179464.1_Sparadoxus | cds-NP_012150.1_Sparadoxus | 90.5 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |