Gene name: HIS2
Reference locus (S288C): YFR025C
Gene biotype: protein_coding
Description: Histidinol-phosphatase; Histidinolphosphatase; catalyzes the eighth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control
Top 10 interactors (score): HIS4 (0.992); HIS5 (0.972); HIS1 (0.871); GCN4 (0.841); ADE1 (0.813); HIS3 (0.802); HIS7 (0.792); TRP1 (0.746); HIS6 (0.725); LEU2 (0.717); URA3 (0.685); ARG4 (0.684); TRP3 (0.642); LYS1 (0.58); SMC2 (0.506); TRP4 (0.499); UBS1 (0.499); YCS4 (0.495); LEU4 (0.483); YFR045W (0.456)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005300.1:193948-194955:- | gene-YFR025C_AKU4011 | rna-NM_001179990.1_AKU4011 | cds-NP_116681.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000071.1:65709-66716:+ | gene-YFR025C_BG1 | rna-NM_001179990.1_BG1 | cds-NP_116681.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005508.1:196788-197795:- | gene-YFR025C_Bruggeman | rna-NM_001179990.1_Bruggeman | cds-NP_116681.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005524.1:199317-200324:- | gene-YFR025C_CAT1 | rna-NM_001179990.1_CAT1 | cds-NP_116681.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005364.1:195439-196446:- | gene-YFR025C_CBS1585 | rna-NM_001179990.1_CBS1585 | cds-NP_116681.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005348.1:168669-169676:- | gene-YFR025C_CBS436 | rna-NM_001179990.1_CBS436 | cds-NP_116681.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005332.1:194520-195527:- | gene-YFR025C_CBS6412 | rna-NM_001179990.1_CBS6412 | cds-NP_116681.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005316.1:197175-198182:- | gene-YFR025C_CBS6413 | rna-NM_001179990.1_CBS6413 | cds-NP_116681.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001527.1:199786-200793:- | gene-YFR025C_CENPK1137D | rna-NM_001179990.1_CENPK1137D | cds-NP_116681.1_CENPK1137D | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005476.1:193056-194063:- | gene-YFR025C_EthanolRed | rna-NM_001179990.1_EthanolRed | cds-NP_116681.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005540.1:194706-195713:- | gene-YFR025C_FaliES1 | rna-NM_001179990.1_FaliES1 | cds-NP_116681.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000452.1:41462-42469:- | gene-YFR025C_JAY291 | rna-NM_001179990.1_JAY291 | cds-NP_116681.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005412.1:197267-198274:- | gene-YFR025C_MUCL30387 | rna-NM_001179990.1_MUCL30387 | cds-NP_116681.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005444.1:193524-194531:- | gene-YFR025C_MUCL30388 | rna-NM_001179990.1_MUCL30388 | cds-NP_116681.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005284.1:193358-194365:- | gene-YFR025C_MUCL39482 | rna-NM_001179990.1_MUCL39482 | cds-NP_116681.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005428.1:192666-193673:- | gene-YFR025C_MUCL42920 | rna-NM_001179990.1_MUCL42920 | cds-NP_116681.1_MUCL42920 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011815.1:203742-204749:- | gene-YFR025C_NCIM3186 | rna-NM_001179990.1_NCIM3186 | cds-NP_116681.1_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005268.1:194240-195247:- | gene-YFR025C_NCYC1407 | rna-NM_001179990.1_NCYC1407 | cds-NP_116681.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994145.1:236676-237683:- | gene-YFR025C_PE2H3 | rna-NM_001179990.1_PE2H3 | cds-NP_116681.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999877.1:236224-237231:- | gene-YFR025C_PE2H4 | rna-NM_001179990.1_PE2H4 | cds-NP_116681.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001138.5:203743-204750:- | gene-YFR025C_S288C | rna-NM_001179990.1_S288C | cds-NP_116681.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000011.1:119685-120692:+ | gene-YFR025C_SA1 | rna-NM_001179990.1_SA1 | cds-NP_116681.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005492.1:193863-194870:- | gene-YFR025C_ThermosaccDry | rna-NM_001179990.1_ThermosaccDry | cds-NP_116681.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005460.1:209907-210914:- | gene-YFR025C_VR1 | rna-NM_001179990.1_VR1 | cds-NP_116681.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000013.1:124336-125343:- | gene-YFR025C_ZTW1 | rna-NM_001179990.1_ZTW1 | cds-NP_116681.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047492.1:217816-218823:- | gene-YFR025C_Sparadoxus | rna-NM_001179990.1_Sparadoxus | cds-NP_116681.1_Sparadoxus | 90.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |