Gene name: HIS1
Reference locus (S288C): YER055C
Gene biotype: protein_coding
Description: ATP phosphoribosyltransferase; a hexameric enzyme, catalyzes the first step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control
Top 10 interactors (score): HIS4 (0.999); ARG4 (0.985); HIS3 (0.983); HIS7 (0.979); HIS5 (0.978); TRP5 (0.961); URA3 (0.932); LEU2 (0.929); MET3 (0.923); PRS2 (0.917); TRP3 (0.912); ARG5,6 (0.908); DUR3 (0.906); HIS6 (0.905); ILV5 (0.884); HIS2 (0.871); PRS1 (0.849); ILV6 (0.847); PRS4 (0.842); PRS3 (0.835)
Homologues (species, bitscore): ATP-PRT2 (Arabidopsis thaliana, 73.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:258691-259584:- | gene-YER055C_AKU4011 | rna-NM_001178946.3_AKU4011 | cds-NP_010975.3_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000011.1:166194-167087:+ | gene-YER055C_BG1 | rna-NM_001178946.3_BG1 | cds-NP_010975.3_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:267480-268373:- | gene-YER055C_Bruggeman | rna-NM_001178946.3_Bruggeman | cds-NP_010975.3_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:261641-262534:- | gene-YER055C_CAT1 | rna-NM_001178946.3_CAT1 | cds-NP_010975.3_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:258547-259440:- | gene-YER055C_CBS1585 | rna-NM_001178946.3_CBS1585 | cds-NP_010975.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:260453-261346:- | gene-YER055C_CBS436 | rna-NM_001178946.3_CBS436 | cds-NP_010975.3_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:258016-258909:- | gene-YER055C_CBS6412 | rna-NM_001178946.3_CBS6412 | cds-NP_010975.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:264024-264917:- | gene-YER055C_CBS6413 | rna-NM_001178946.3_CBS6413 | cds-NP_010975.3_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:262757-263650:- | gene-YER055C_CENPK1137D | rna-NM_001178946.3_CENPK1137D | cds-NP_010975.3_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:259030-259923:- | gene-YER055C_EthanolRed | rna-NM_001178946.3_EthanolRed | cds-NP_010975.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:259484-260377:- | gene-YER055C_FaliES1 | rna-NM_001178946.3_FaliES1 | cds-NP_010975.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000406.1:918-1811:+ | gene-YER055C_JAY291 | rna-NM_001178946.3_JAY291 | cds-NP_010975.3_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:262926-263819:- | gene-YER055C_MUCL30387 | rna-NM_001178946.3_MUCL30387 | cds-NP_010975.3_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:259116-260009:- | gene-YER055C_MUCL30388 | rna-NM_001178946.3_MUCL30388 | cds-NP_010975.3_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:257581-258474:- | gene-YER055C_MUCL39482 | rna-NM_001178946.3_MUCL39482 | cds-NP_010975.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:264638-265531:- | gene-YER055C_MUCL42920 | rna-NM_001178946.3_MUCL42920 | cds-NP_010975.3_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:264891-265784:- | gene-YER055C_NCIM3186 | rna-NM_001178946.3_NCIM3186 | cds-NP_010975.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:262645-263538:- | gene-YER055C_NCYC1407 | rna-NM_001178946.3_NCYC1407 | cds-NP_010975.3_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:273286-274179:- | gene-YER055C_PE2H3 | rna-NM_001178946.3_PE2H3 | cds-NP_010975.3_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:263227-264120:- | gene-YER055C_PE2H4 | rna-NM_001178946.3_PE2H4 | cds-NP_010975.3_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:264892-265785:- | gene-YER055C_S288C | rna-NM_001178946.3_S288C | cds-NP_010975.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000059.1:51416-52309:- | gene-YER055C_SA1 | rna-NM_001178946.3_SA1 | cds-NP_010975.3_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:260281-261174:- | gene-YER055C_ThermosaccDry | rna-NM_001178946.3_ThermosaccDry | cds-NP_010975.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:259350-260243:- | gene-YER055C_VR1 | rna-NM_001178946.3_VR1 | cds-NP_010975.3_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000009.1:257468-258361:- | gene-YER055C_ZTW1 | rna-NM_001178946.3_ZTW1 | cds-NP_010975.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:261355-262248:- | gene-YER055C_Sparadoxus | rna-NM_001178946.3_Sparadoxus | cds-NP_010975.3_Sparadoxus | 90.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |