HIR2 (YOR038C)


Gene profile

Gene name: HIR2
Reference locus (S288C): YOR038C
Gene biotype: protein_coding

Description: Protein HIR2; Subunit of HIR nucleosome assembly complex; involved in regulation of histone gene transcription; recruits Swi-Snf complexes to histone gene promoters; promotes heterochromatic gene silencing with Asf1p; relocalizes to the cytosol in response to hypoxia

Top 10 interactors (score): HPC2 (0.999); HIR3 (0.999); ASF1 (0.999); HIR1 (0.996); CAC2 (0.979); MSI1 (0.975); RTT106 (0.971); RLF2 (0.936); HHT1 (0.932); SPT10 (0.898); HHT2 (0.884); HTA1 (0.864); HHF1 (0.861); SPT16 (0.853); SNF5 (0.851); SPT21 (0.844); HTB1 (0.829); DBP3 (0.815); SPT6 (0.805); SPT2 (0.799)

Homologues (species, bitscore): HIRA (Homo sapiens, 89.7); Hira (Mus musculus, 86.7); hira (Danio rerio, 86.7); hira (Xenopus tropicalis, 104.8); Hira (Drosophila melanogaster, 67.8); HIRA (Arabidopsis thaliana, 107.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:387102-389729:- gene-YOR038C_AKU4011 rna-NM_001183457.1_AKU4011 cds-NP_014681.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000152.1:202678-205305:- gene-YOR038C_BG1 rna-NM_001183457.1_BG1 cds-NP_014681.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:389843-392470:- gene-YOR038C_Bruggeman rna-NM_001183457.1_Bruggeman cds-NP_014681.1_Bruggeman 99.9 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:387996-390623:- gene-YOR038C_CAT1 rna-NM_001183457.1_CAT1 cds-NP_014681.1_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:381793-384420:- gene-YOR038C_CBS1585 rna-NM_001183457.1_CBS1585 cds-NP_014681.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:386147-388774:- gene-YOR038C_CBS436 rna-NM_001183457.1_CBS436 cds-NP_014681.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:381147-383774:- gene-YOR038C_CBS6412 rna-NM_001183457.1_CBS6412 cds-NP_014681.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:388522-391149:- gene-YOR038C_CBS6413 rna-NM_001183457.1_CBS6413 cds-NP_014681.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:402760-405387:- gene-YOR038C_CENPK1137D rna-NM_001183457.1_CENPK1137D cds-NP_014681.1_CENPK1137D 99.6 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:383800-386427:- gene-YOR038C_EthanolRed rna-NM_001183457.1_EthanolRed cds-NP_014681.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:387148-389775:- gene-YOR038C_FaliES1 rna-NM_001183457.1_FaliES1 cds-NP_014681.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000035.1:57795-60422:- gene-YOR038C_JAY291 rna-NM_001183457.1_JAY291 cds-NP_014681.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:394611-397238:- gene-YOR038C_MUCL30387 rna-NM_001183457.1_MUCL30387 cds-NP_014681.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:397915-400542:- gene-YOR038C_MUCL30388 rna-NM_001183457.1_MUCL30388 cds-NP_014681.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:389276-391903:- gene-YOR038C_MUCL39482 rna-NM_001183457.1_MUCL39482 cds-NP_014681.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:404090-406717:- gene-YOR038C_MUCL42920 rna-NM_001183457.1_MUCL42920 cds-NP_014681.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:402650-405277:- gene-YOR038C_NCIM3186 rna-NM_001183457.1_NCIM3186 cds-NP_014681.1_NCIM3186 99.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:395978-398605:- gene-YOR038C_NCYC1407 rna-NM_001183457.1_NCYC1407 cds-NP_014681.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:394814-397441:- gene-YOR038C_PE2H3 rna-NM_001183457.1_PE2H3 cds-NP_014681.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:405195-407822:- gene-YOR038C_PE2H4 rna-NM_001183457.1_PE2H4 cds-NP_014681.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:402761-405388:- gene-YOR038C_S288C rna-NM_001183457.1_S288C cds-NP_014681.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000001.1:370679-373306:- gene-YOR038C_SA1 rna-NM_001183457.1_SA1 cds-NP_014681.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:385688-388315:- gene-YOR038C_ThermosaccDry rna-NM_001183457.1_ThermosaccDry cds-NP_014681.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:386577-389204:- gene-YOR038C_VR1 rna-NM_001183457.1_VR1 cds-NP_014681.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:120314-122941:- gene-YOR038C_ZTW1 rna-NM_001183457.1_ZTW1 cds-NP_014681.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:393030-395657:- gene-YOR038C_Sparadoxus rna-NM_001183457.1_Sparadoxus cds-NP_014681.1_Sparadoxus 91.3 100.0 Verified 1 1 1 False True False False False

Additional files