Gene name: HHO1
Reference locus (S288C): YPL127C
Gene biotype: protein_coding
Description: Histone H1, linker histone with roles in meiosis and sporulation; decreasing levels early in sporulation may promote meiosis, and increasing levels during sporulation facilitate compaction of spore chromatin; binds to promoters and within genes in mature spores; may be recruited by Ume6p to promoter regions, contributing to transcriptional repression outside of meiosis; suppresses DNA repair involving homologous recombination; Belongs to the histone H1/H5 family
Top 10 interactors (score): HTA2 (0.994); HTZ1 (0.994); CDC28 (0.991); HTA1 (0.99); HHF1 (0.989); HHT1 (0.988); HHT2 (0.987); HTB1 (0.982); HTB2 (0.981); HHF2 (0.976); NHP6A (0.876); CLB2 (0.85); GCN5 (0.844); HMO1 (0.839); ASF1 (0.816); SIR2 (0.806); RAD53 (0.806); TUB1 (0.782); CHD1 (0.781); SWE1 (0.77)
Homologues (species, bitscore): H1f0 (Mus musculus, 53.1); zgc:110425 (Danio rerio, 50.1); h1f0 (Xenopus tropicalis, 56.2); hil-4 (Caenorhabditis elegans, 52.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:286481-287257:- | gene-YPL127C_AKU4011 | rna-NM_001183941.1_AKU4011 | cds-NP_015198.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:492168-492944:- | gene-YPL127C_BG1 | rna-NM_001183941.1_BG1 | cds-NP_015198.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:312480-313256:- | gene-YPL127C_Bruggeman | rna-NM_001183941.1_Bruggeman | cds-NP_015198.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:309151-309927:- | gene-YPL127C_CAT1 | rna-NM_001183941.1_CAT1 | cds-NP_015198.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:290554-291330:- | gene-YPL127C_CBS1585 | rna-NM_001183941.1_CBS1585 | cds-NP_015198.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:305218-305994:- | gene-YPL127C_CBS436 | rna-NM_001183941.1_CBS436 | cds-NP_015198.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:295223-295999:- | gene-YPL127C_CBS6412 | rna-NM_001183941.1_CBS6412 | cds-NP_015198.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:287190-287966:- | gene-YPL127C_CBS6413 | rna-NM_001183941.1_CBS6413 | cds-NP_015198.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:308730-309506:- | gene-YPL127C_CENPK1137D | rna-NM_001183941.1_CENPK1137D | cds-NP_015198.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:285169-285945:- | gene-YPL127C_EthanolRed | rna-NM_001183941.1_EthanolRed | cds-NP_015198.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:292761-293537:- | gene-YPL127C_FaliES1 | rna-NM_001183941.1_FaliES1 | cds-NP_015198.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000007.1:72311-73087:+ | gene-YPL127C_JAY291 | rna-NM_001183941.1_JAY291 | cds-NP_015198.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:303724-304500:- | gene-YPL127C_MUCL30387 | rna-NM_001183941.1_MUCL30387 | cds-NP_015198.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:301733-302509:- | gene-YPL127C_MUCL30388 | rna-NM_001183941.1_MUCL30388 | cds-NP_015198.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:283883-284659:- | gene-YPL127C_MUCL39482 | rna-NM_001183941.1_MUCL39482 | cds-NP_015198.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:341121-341897:- | gene-YPL127C_MUCL42920 | rna-NM_001183941.1_MUCL42920 | cds-NP_015198.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:308811-309587:- | gene-YPL127C_NCIM3186 | rna-NM_001183941.1_NCIM3186 | cds-NP_015198.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:290336-291112:- | gene-YPL127C_NCYC1407 | rna-NM_001183941.1_NCYC1407 | cds-NP_015198.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:297794-298570:- | gene-YPL127C_PE2H3 | rna-NM_001183941.1_PE2H3 | cds-NP_015198.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:297417-298193:- | gene-YPL127C_PE2H4 | rna-NM_001183941.1_PE2H4 | cds-NP_015198.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:308828-309604:- | gene-YPL127C_S288C | rna-NM_001183941.1_S288C | cds-NP_015198.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000012.1:64076-64852:+ | gene-YPL127C_SA1 | rna-NM_001183941.1_SA1 | cds-NP_015198.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:292559-293335:- | gene-YPL127C_ThermosaccDry | rna-NM_001183941.1_ThermosaccDry | cds-NP_015198.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:307537-308313:- | gene-YPL127C_VR1 | rna-NM_001183941.1_VR1 | cds-NP_015198.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:291885-292661:- | gene-YPL127C_ZTW1 | rna-NM_001183941.1_ZTW1 | cds-NP_015198.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:293642-294418:- | gene-YPL127C_Sparadoxus | rna-NM_001183941.1_Sparadoxus | cds-NP_015198.1_Sparadoxus | 91.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |