HGH1 (YGR187C)


Gene profile

Gene name: HGH1
Reference locus (S288C): YGR187C
Gene biotype: protein_coding

Description: Nonessential protein of unknown function; predicted to be involved in ribosome biogenesis; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; similar to mammalian BRP16 (Brain protein 16); relative distribution to the nucleus increases upon DNA replication stress

Top 10 interactors (score): CNS1 (0.998); NOP4 (0.984); IMP4 (0.971); YTM1 (0.958); SSF1 (0.946); DBP3 (0.94); UTP5 (0.932); RRB1 (0.93); PUF6 (0.929); PWP1 (0.926); CIC1 (0.917); SYO1 (0.915); RRS1 (0.914); NOP15 (0.898); RRT14 (0.897); MRT4 (0.896); YPL225W (0.893); NOB1 (0.882); RPF2 (0.88); BMT5 (0.871)

Homologues (species, bitscore): HGH1 (Homo sapiens, 134.4); Fam203a (Mus musculus, 116.3); fam203a (Danio rerio, 109.8); CG6073 (Drosophila melanogaster, 85.1); Y54H5A.2 (Caenorhabditis elegans, 64.3); AT1G14300 (Arabidopsis thaliana, 62.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:837986-839170:- gene-YGR187C_AKU4011 rna-NM_001181316.3_AKU4011 cds-NP_011703.3_AKU4011 99.5 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000021.1:116095-117279:- gene-YGR187C_BG1 rna-NM_001181316.3_BG1 cds-NP_011703.3_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:843914-845098:- gene-YGR187C_Bruggeman rna-NM_001181316.3_Bruggeman cds-NP_011703.3_Bruggeman 99.3 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:840014-841198:- gene-YGR187C_CAT1 rna-NM_001181316.3_CAT1 cds-NP_011703.3_CAT1 99.5 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:838702-839886:- gene-YGR187C_CBS1585 rna-NM_001181316.3_CBS1585 cds-NP_011703.3_CBS1585 99.5 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:842592-843776:- gene-YGR187C_CBS436 rna-NM_001181316.3_CBS436 cds-NP_011703.3_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:830072-831256:- gene-YGR187C_CBS6412 rna-NM_001181316.3_CBS6412 cds-NP_011703.3_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:835568-836752:- gene-YGR187C_CBS6413 rna-NM_001181316.3_CBS6413 cds-NP_011703.3_CBS6413 99.5 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:869957-871141:- gene-YGR187C_CENPK1137D rna-NM_001181316.3_CENPK1137D cds-NP_011703.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:824577-825761:- gene-YGR187C_EthanolRed rna-NM_001181316.3_EthanolRed cds-NP_011703.3_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:828968-830152:- gene-YGR187C_FaliES1 rna-NM_001181316.3_FaliES1 cds-NP_011703.3_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000364.1:4634-5818:+ gene-YGR187C_JAY291 rna-NM_001181316.3_JAY291 cds-NP_011703.3_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:841404-842588:- gene-YGR187C_MUCL30387 rna-NM_001181316.3_MUCL30387 cds-NP_011703.3_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:841115-842299:- gene-YGR187C_MUCL30388 rna-NM_001181316.3_MUCL30388 cds-NP_011703.3_MUCL30388 99.2 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:834275-835459:- gene-YGR187C_MUCL39482 rna-NM_001181316.3_MUCL39482 cds-NP_011703.3_MUCL39482 99.4 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:850894-852078:- gene-YGR187C_MUCL42920 rna-NM_001181316.3_MUCL42920 cds-NP_011703.3_MUCL42920 99.4 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:870232-871416:- gene-YGR187C_NCIM3186 rna-NM_001181316.3_NCIM3186 cds-NP_011703.3_NCIM3186 96.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:829385-830569:- gene-YGR187C_NCYC1407 rna-NM_001181316.3_NCYC1407 cds-NP_011703.3_NCYC1407 99.5 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:848579-849763:- gene-YGR187C_PE2H3 rna-NM_001181316.3_PE2H3 cds-NP_011703.3_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:853689-854873:- gene-YGR187C_PE2H4 rna-NM_001181316.3_PE2H4 cds-NP_011703.3_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:870232-871416:- gene-YGR187C_S288C rna-NM_001181316.3_S288C cds-NP_011703.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000035.1:93950-95134:- gene-YGR187C_SA1 rna-NM_001181316.3_SA1 cds-NP_011703.3_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:849479-850663:- gene-YGR187C_ThermosaccDry rna-NM_001181316.3_ThermosaccDry cds-NP_011703.3_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:953724-954908:- gene-YGR187C_VR1 rna-NM_001181316.3_VR1 cds-NP_011703.3_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000016.1:150914-152098:- gene-YGR187C_ZTW1 rna-NM_001181316.3_ZTW1 cds-NP_011703.3_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:841091-842278:- gene-YGR187C_Sparadoxus rna-NM_001181316.3_Sparadoxus cds-NP_011703.3_Sparadoxus 89.8 100.0 Verified 1 1 1 False True False False False

Additional files