Gene name: HFM1
Reference locus (S288C): YGL251C
Gene biotype: protein_coding
Description: Meiosis specific DNA helicase; involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control; catalyzes the unwinding of Holliday junctions; has ssDNA and dsDNA stimulated ATPase activity
Top 10 interactors (score): MSH4 (0.993); MSH5 (0.98); SPO22 (0.972); MUS81 (0.958); SPO11 (0.957); MND1 (0.946); SPO16 (0.943); MLH1 (0.923); MLH3 (0.921); PRP8 (0.898); MER1 (0.898); PCH2 (0.894); LRG1 (0.886); REC107 (0.882); BUD13 (0.876); AMA1 (0.857); DMC1 (0.853); NAM8 (0.821); ZIP1 (0.813); EXO1 (0.803)
Homologues (species, bitscore): HFM1 (Homo sapiens, 458.0); Hfm1 (Mus musculus, 450.7); hfm1 (Danio rerio, 455.7); Ascc3 (Xenopus tropicalis, 285.0); CG5205 (Drosophila melanogaster, 307.8); snrp-200 (Caenorhabditis elegans, 263.1); RCK (Arabidopsis thaliana, 401.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:29445-33160:- | gene-YGL251C_AKU4011 | rna-NM_001181117.1_AKU4011 | cds-NP_011263.2_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000175.1:21485-25200:- | gene-YGL251C_BG1 | rna-NM_001181117.1_BG1 | cds-NP_011263.2_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:29801-33516:- | gene-YGL251C_Bruggeman | rna-NM_001181117.1_Bruggeman | cds-NP_011263.2_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:27873-31588:- | gene-YGL251C_CAT1 | rna-NM_001181117.1_CAT1 | cds-NP_011263.2_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:33733-37448:- | gene-YGL251C_CBS1585 | rna-NM_001181117.1_CBS1585 | cds-NP_011263.2_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:28462-32177:- | gene-YGL251C_CBS436 | rna-NM_001181117.1_CBS436 | cds-NP_011263.2_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:21301-25016:- | gene-YGL251C_CBS6412 | rna-NM_001181117.1_CBS6412 | cds-NP_011263.2_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:27589-31304:- | gene-YGL251C_CBS6413 | rna-NM_001181117.1_CBS6413 | cds-NP_011263.2_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:27583-31298:- | gene-YGL251C_CENPK1137D | rna-NM_001181117.1_CENPK1137D | cds-NP_011263.2_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:20722-24437:- | gene-YGL251C_EthanolRed | rna-NM_001181117.1_EthanolRed | cds-NP_011263.2_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:21083-24798:- | gene-YGL251C_FaliES1 | rna-NM_001181117.1_FaliES1 | cds-NP_011263.2_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000079.1:42282-45997:+ | gene-YGL251C_JAY291 | rna-NM_001181117.1_JAY291 | cds-NP_011263.2_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:29737-33452:- | gene-YGL251C_MUCL30387 | rna-NM_001181117.1_MUCL30387 | cds-NP_011263.2_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:31891-35606:- | gene-YGL251C_MUCL30388 | rna-NM_001181117.1_MUCL30388 | cds-NP_011263.2_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:30330-34045:- | gene-YGL251C_MUCL39482 | rna-NM_001181117.1_MUCL39482 | cds-NP_011263.2_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:33224-36939:- | gene-YGL251C_MUCL42920 | rna-NM_001181117.1_MUCL42920 | cds-NP_011263.2_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:27921-31636:- | gene-YGL251C_NCIM3186 | rna-NM_001181117.1_NCIM3186 | cds-NP_011263.2_NCIM3186 | 97.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:22094-25809:- | gene-YGL251C_NCYC1407 | rna-NM_001181117.1_NCYC1407 | cds-NP_011263.2_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:23950-27665:- | gene-YGL251C_PE2H3 | rna-NM_001181117.1_PE2H3 | cds-NP_011263.2_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:23498-27213:- | gene-YGL251C_PE2H4 | rna-NM_001181117.1_PE2H4 | cds-NP_011263.2_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:27921-31636:- | gene-YGL251C_S288C | rna-NM_001181117.1_S288C | cds-NP_011263.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:343698-347413:+ | gene-YGL251C_SA1 | rna-NM_001181117.1_SA1 | cds-NP_011263.2_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:21398-25113:- | gene-YGL251C_ThermosaccDry | rna-NM_001181117.1_ThermosaccDry | cds-NP_011263.2_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:28388-32103:- | gene-YGL251C_VR1 | rna-NM_001181117.1_VR1 | cds-NP_011263.2_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:20472-24187:- | gene-YGL251C_ZTW1 | rna-NM_001181117.1_ZTW1 | cds-NP_011263.2_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:29136-32851:- | gene-YGL251C_Sparadoxus | rna-NM_001181117.1_Sparadoxus | cds-NP_011263.2_Sparadoxus | 87.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |