Gene name: HES1
Reference locus (S288C): YOR237W
Gene biotype: protein_coding
Description: Oxysterol-binding protein-related protein 9/10/11; Protein implicated in the regulation of ergosterol biosynthesis; one of a seven member gene family with a common essential function and non-essential unique functions; similar to human oxysterol binding protein (OSBP); SWAT-GFP and mCherry fusion proteins localize to the bud neck and vacuolar membrane; HES1 has a paralog, KES1, that arose from the whole genome duplication
Top 10 interactors (score): YML083C (0.723); DAN1 (0.718); OSH3 (0.706); OSH2 (0.697); SWH1 (0.682); TIR4 (0.672); OSH7 (0.667); PAU14 (0.659); PAU1 (0.658); GUP2 (0.606); PAU8 (0.6); KES1 (0.592); SEC14 (0.584); SRT1 (0.567); AUS1 (0.567); PAU24 (0.566); SCS2 (0.563); SLM2 (0.563); UPC2 (0.54); ERG28 (0.538)
Homologues (species, bitscore): OSBPL9 (Homo sapiens, 128.3); Osbpl9 (Mus musculus, 127.5); osbpl9 (Danio rerio, 121.7); osbpl9 (Xenopus tropicalis, 134.8); CG1513 (Drosophila melanogaster, 132.9); obr-4 (Caenorhabditis elegans, 111.7); ORP4C (Arabidopsis thaliana, 78.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:772768-774072:+ | gene-YOR237W_AKU4011 | rna-NM_001183656.3_AKU4011 | cds-NP_014880.3_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:174806-176110:+ | gene-YOR237W_BG1 | rna-NM_001183656.3_BG1 | cds-NP_014880.3_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:758233-759537:+ | gene-YOR237W_Bruggeman | rna-NM_001183656.3_Bruggeman | cds-NP_014880.3_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:758883-760187:+ | gene-YOR237W_CAT1 | rna-NM_001183656.3_CAT1 | cds-NP_014880.3_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:755757-757061:+ | gene-YOR237W_CBS1585 | rna-NM_001183656.3_CBS1585 | cds-NP_014880.3_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:754450-755754:+ | gene-YOR237W_CBS436 | rna-NM_001183656.3_CBS436 | cds-NP_014880.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:752876-754180:+ | gene-YOR237W_CBS6412 | rna-NM_001183656.3_CBS6412 | cds-NP_014880.3_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:761516-762820:+ | gene-YOR237W_CBS6413 | rna-NM_001183656.3_CBS6413 | cds-NP_014880.3_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:781756-783060:+ | gene-YOR237W_CENPK1137D | rna-NM_001183656.3_CENPK1137D | cds-NP_014880.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:748888-750192:+ | gene-YOR237W_EthanolRed | rna-NM_001183656.3_EthanolRed | cds-NP_014880.3_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:754287-755591:+ | gene-YOR237W_FaliES1 | rna-NM_001183656.3_FaliES1 | cds-NP_014880.3_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000381.1:71249-72553:- | gene-YOR237W_JAY291 | rna-NM_001183656.3_JAY291 | cds-NP_014880.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:762504-763808:+ | gene-YOR237W_MUCL30387 | rna-NM_001183656.3_MUCL30387 | cds-NP_014880.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:769622-770926:+ | gene-YOR237W_MUCL30388 | rna-NM_001183656.3_MUCL30388 | cds-NP_014880.3_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:763087-764391:+ | gene-YOR237W_MUCL39482 | rna-NM_001183656.3_MUCL39482 | cds-NP_014880.3_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:772674-773978:+ | gene-YOR237W_MUCL42920 | rna-NM_001183656.3_MUCL42920 | cds-NP_014880.3_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:781883-783187:+ | gene-YOR237W_NCIM3186 | rna-NM_001183656.3_NCIM3186 | cds-NP_014880.3_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:763186-764490:+ | gene-YOR237W_NCYC1407 | rna-NM_001183656.3_NCYC1407 | cds-NP_014880.3_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:762486-763790:+ | gene-YOR237W_PE2H3 | rna-NM_001183656.3_PE2H3 | cds-NP_014880.3_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:772863-774167:+ | gene-YOR237W_PE2H4 | rna-NM_001183656.3_PE2H4 | cds-NP_014880.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:781994-783298:+ | gene-YOR237W_S288C | rna-NM_001183656.3_S288C | cds-NP_014880.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:191987-193291:+ | gene-YOR237W_SA1 | rna-NM_001183656.3_SA1 | cds-NP_014880.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:753470-754774:+ | gene-YOR237W_ThermosaccDry | rna-NM_001183656.3_ThermosaccDry | cds-NP_014880.3_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:816926-818230:+ | gene-YOR237W_VR1 | rna-NM_001183656.3_VR1 | cds-NP_014880.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:486388-487692:+ | gene-YOR237W_ZTW1 | rna-NM_001183656.3_ZTW1 | cds-NP_014880.3_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:759376-760677:+ | gene-YOR237W_Sparadoxus | rna-NM_001183656.3_Sparadoxus | cds-NP_014880.3_Sparadoxus | 91.3 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |