HER2 (YMR293C)


Gene profile

Gene name: HER2
Reference locus (S288C): YMR293C
Gene biotype: protein_coding

Description: Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; required for remodeling of ER caused by Hmg2p overexpression; similar to bacterial GatA glutamyl-tRNA amidotransferase

Top 10 interactors (score): PET112 (0.999); GTF1 (0.998); SLM5 (0.982); GLN4 (0.965); DED81 (0.944); MSE1 (0.896); GUS1 (0.891); HER1 (0.815); MSD1 (0.808); YNR021W (0.748); RRG7 (0.745); RRG8 (0.717); GEP5 (0.714); YDR114C (0.712); PCA1 (0.712); RRG9 (0.7); MSW1 (0.692); HSC82 (0.684); ISM1 (0.681); CDC5 (0.679)

Homologues (species, bitscore): QRSL1 (Homo sapiens, 229.2); Qrsl1 (Mus musculus, 239.2); qrsl1 (Danio rerio, 236.1); qrsl1 (Xenopus tropicalis, 229.6); gatA (Drosophila melanogaster, 229.9); Y41D4A.6 (Caenorhabditis elegans, 204.9); AT3G25660 (Arabidopsis thaliana, 242.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:894448-895842:- gene-YMR293C_AKU4011 rna-NM_001182801.1_AKU4011 cds-NP_014021.1_AKU4011 99.1 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000069.1:57860-59254:+ gene-YMR293C_BG1 rna-NM_001182801.1_BG1 cds-NP_014021.1_BG1 99.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:839660-841054:- gene-YMR293C_Bruggeman rna-NM_001182801.1_Bruggeman cds-NP_014021.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:842941-844335:- gene-YMR293C_CAT1 rna-NM_001182801.1_CAT1 cds-NP_014021.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:826699-828093:- gene-YMR293C_CBS1585 rna-NM_001182801.1_CBS1585 cds-NP_014021.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:849017-850411:- gene-YMR293C_CBS436 rna-NM_001182801.1_CBS436 cds-NP_014021.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:938274-939668:- gene-YMR293C_CBS6412 rna-NM_001182801.1_CBS6412 cds-NP_014021.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:825818-827212:- gene-YMR293C_CBS6413 rna-NM_001182801.1_CBS6413 cds-NP_014021.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:849943-851337:- gene-YMR293C_CENPK1137D rna-NM_001182801.1_CENPK1137D cds-NP_014021.1_CENPK1137D 99.2 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:887142-888536:- gene-YMR293C_EthanolRed rna-NM_001182801.1_EthanolRed cds-NP_014021.1_EthanolRed 99.0 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:833169-834563:- gene-YMR293C_FaliES1 rna-NM_001182801.1_FaliES1 cds-NP_014021.1_FaliES1 99.0 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000262.1:17171-18565:+ gene-YMR293C_JAY291 rna-NM_001182801.1_JAY291 cds-NP_014021.1_JAY291 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:833484-834878:- gene-YMR293C_MUCL30387 rna-NM_001182801.1_MUCL30387 cds-NP_014021.1_MUCL30387 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:842874-844268:- gene-YMR293C_MUCL30388 rna-NM_001182801.1_MUCL30388 cds-NP_014021.1_MUCL30388 99.0 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:827764-829158:- gene-YMR293C_MUCL39482 rna-NM_001182801.1_MUCL39482 cds-NP_014021.1_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:836588-837982:- gene-YMR293C_MUCL42920 rna-NM_001182801.1_MUCL42920 cds-NP_014021.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:855353-856747:- gene-YMR293C_NCIM3186 rna-NM_001182801.1_NCIM3186 cds-NP_014021.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:827418-828812:- gene-YMR293C_NCYC1407 rna-NM_001182801.1_NCYC1407 cds-NP_014021.1_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:843238-844632:- gene-YMR293C_PE2H3 rna-NM_001182801.1_PE2H3 cds-NP_014021.1_PE2H3 99.2 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:839213-840607:- gene-YMR293C_PE2H4 rna-NM_001182801.1_PE2H4 cds-NP_014021.1_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:855399-856793:- gene-YMR293C_S288C rna-NM_001182801.1_S288C cds-NP_014021.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000036.1:33195-34589:- gene-YMR293C_SA1 rna-NM_001182801.1_SA1 cds-NP_014021.1_SA1 99.2 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:829337-830731:- gene-YMR293C_ThermosaccDry rna-NM_001182801.1_ThermosaccDry cds-NP_014021.1_ThermosaccDry 99.0 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:843091-844485:- gene-YMR293C_VR1 rna-NM_001182801.1_VR1 cds-NP_014021.1_VR1 99.2 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000028.1:244573-245967:- gene-YMR293C_ZTW1 rna-NM_001182801.1_ZTW1 cds-NP_014021.1_ZTW1 99.0 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:847977-849371:- gene-YMR293C_Sparadoxus rna-NM_001182801.1_Sparadoxus cds-NP_014021.1_Sparadoxus 89.2 100.0 Verified 1 1 1 False True False False False

Additional files