HER1 (YOR227W)


Gene profile

Gene name: HER1
Reference locus (S288C): YOR227W
Gene biotype: protein_coding

Description: HMG2-induced ER-remodeling protein 1; Protein of unknown function; required for proliferation or remodeling of the ER that is caused by overexpression of Hmg2p; may interact with ribosomes, based on co-purification experiments; HER1 has a paralog, GIP3, that arose from the whole genome duplication

Top 10 interactors (score): HER2 (0.815); GLC7 (0.758); ALY1 (0.745); YDL176W (0.715); CMR2 (0.712); TRI1 (0.696); NOP2 (0.603); MPP6 (0.574); SEA4 (0.489); NKP1 (0.487); CWC23 (0.485); NKP2 (0.485); LIN1 (0.481); BNI4 (0.461); RTK1 (0.454); PRP4 (0.45)

Homologues (species, bitscore): MUC5AC (Homo sapiens, 62.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:753607-757347:+ gene-YOR227W_AKU4011 rna-NM_001183646.1_AKU4011 cds-NP_014870.1_AKU4011 99.1 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000123.1:155640-159380:+ gene-YOR227W_BG1 rna-NM_001183646.1_BG1 cds-NP_014870.1_BG1 99.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:739070-742810:+ gene-YOR227W_Bruggeman rna-NM_001183646.1_Bruggeman cds-NP_014870.1_Bruggeman 99.3 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:739717-743457:+ gene-YOR227W_CAT1 rna-NM_001183646.1_CAT1 cds-NP_014870.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:736593-740333:+ gene-YOR227W_CBS1585 rna-NM_001183646.1_CBS1585 cds-NP_014870.1_CBS1585 99.0 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:735282-739022:+ gene-YOR227W_CBS436 rna-NM_001183646.1_CBS436 cds-NP_014870.1_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:733713-737453:+ gene-YOR227W_CBS6412 rna-NM_001183646.1_CBS6412 cds-NP_014870.1_CBS6412 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:742352-746092:+ gene-YOR227W_CBS6413 rna-NM_001183646.1_CBS6413 cds-NP_014870.1_CBS6413 99.1 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:762592-766332:+ gene-YOR227W_CENPK1137D rna-NM_001183646.1_CENPK1137D cds-NP_014870.1_CENPK1137D 99.3 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:729744-733484:+ gene-YOR227W_EthanolRed rna-NM_001183646.1_EthanolRed cds-NP_014870.1_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:735141-738881:+ gene-YOR227W_FaliES1 rna-NM_001183646.1_FaliES1 cds-NP_014870.1_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000381.1:87881-91621:- gene-YOR227W_JAY291 rna-NM_001183646.1_JAY291 cds-NP_014870.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:742407-746147:+ gene-YOR227W_MUCL30387 rna-NM_001183646.1_MUCL30387 cds-NP_014870.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:749826-754195:+ gene-YOR227W_MUCL30388 rna-NM_001183646.1_MUCL30388 cds-NP_014870.1_MUCL30388 85.4 100.0 Unannotated 1 1 0 False False False True False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:743923-747663:+ gene-YOR227W_MUCL39482 rna-NM_001183646.1_MUCL39482 cds-NP_014870.1_MUCL39482 99.1 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:753504-757244:+ gene-YOR227W_MUCL42920 rna-NM_001183646.1_MUCL42920 cds-NP_014870.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:762714-766454:+ gene-YOR227W_NCIM3186 rna-NM_001183646.1_NCIM3186 cds-NP_014870.1_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:744025-747765:+ gene-YOR227W_NCYC1407 rna-NM_001183646.1_NCYC1407 cds-NP_014870.1_NCYC1407 99.1 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:743415-747155:+ gene-YOR227W_PE2H3 rna-NM_001183646.1_PE2H3 cds-NP_014870.1_PE2H3 99.2 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:753792-757532:+ gene-YOR227W_PE2H4 rna-NM_001183646.1_PE2H4 cds-NP_014870.1_PE2H4 99.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:762825-766565:+ gene-YOR227W_S288C rna-NM_001183646.1_S288C cds-NP_014870.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000006.1:172822-176562:+ gene-YOR227W_SA1 rna-NM_001183646.1_SA1 cds-NP_014870.1_SA1 99.2 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:734326-738066:+ gene-YOR227W_ThermosaccDry rna-NM_001183646.1_ThermosaccDry cds-NP_014870.1_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:797856-801596:+ gene-YOR227W_VR1 rna-NM_001183646.1_VR1 cds-NP_014870.1_VR1 99.3 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:467225-470965:+ gene-YOR227W_ZTW1 rna-NM_001183646.1_ZTW1 cds-NP_014870.1_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:740188-743925:+ gene-YOR227W_Sparadoxus rna-NM_001183646.1_Sparadoxus cds-NP_014870.1_Sparadoxus 89.2 99.8 Verified 1 1 1 False True False False False

Additional files