Gene name: HEH2
Reference locus (S288C): YDR458C
Gene biotype: protein_coding
Description: Inner nuclear membrane (INM) protein; contains helix-extension-helix (HEH) motif, nuclear localization signal sequence; targeting to the INM requires the Srp1p-Kap95p karyopherins and the Ran cycle; HEH2 has a paralog, SRC1, that arose from the whole genome duplication
Top 10 interactors (score): SRP1 (0.952); SNF7 (0.84); CHM7 (0.832); POM34 (0.79); DSF1 (0.779); APQ12 (0.771); POM152 (0.766); MAN2 (0.766); POM33 (0.765); NUP2 (0.764); LAP2 (0.749); NUR1 (0.746); MPS3 (0.744); NUP188 (0.721); NUP170 (0.719); IRC23 (0.698); PER33 (0.698); LRS4 (0.685); NUP85 (0.67); NSG1 (0.659)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1319960-1321951:- | gene-YDR458C_AKU4011 | rna-NM_001180766.1_AKU4011 | cds-NP_010746.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000039.1:198319-200310:- | gene-YDR458C_BG1 | rna-NM_001180766.1_BG1 | cds-NP_010746.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1351392-1353383:- | gene-YDR458C_Bruggeman | rna-NM_001180766.1_Bruggeman | cds-NP_010746.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1328542-1330533:- | gene-YDR458C_CAT1 | rna-NM_001180766.1_CAT1 | cds-NP_010746.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1314266-1316257:- | gene-YDR458C_CBS1585 | rna-NM_001180766.1_CBS1585 | cds-NP_010746.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1333640-1335631:- | gene-YDR458C_CBS436 | rna-NM_001180766.1_CBS436 | cds-NP_010746.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1309894-1311885:- | gene-YDR458C_CBS6412 | rna-NM_001180766.1_CBS6412 | cds-NP_010746.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1332905-1334896:- | gene-YDR458C_CBS6413 | rna-NM_001180766.1_CBS6413 | cds-NP_010746.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1378729-1380720:- | gene-YDR458C_CENPK1137D | rna-NM_001180766.1_CENPK1137D | cds-NP_010746.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1323315-1325306:- | gene-YDR458C_EthanolRed | rna-NM_001180766.1_EthanolRed | cds-NP_010746.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1326868-1328859:- | gene-YDR458C_FaliES1 | rna-NM_001180766.1_FaliES1 | cds-NP_010746.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000026.1:25128-27119:- | gene-YDR458C_JAY291 | rna-NM_001180766.1_JAY291 | cds-NP_010746.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1333883-1335874:- | gene-YDR458C_MUCL30387 | rna-NM_001180766.1_MUCL30387 | cds-NP_010746.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1315907-1317898:- | gene-YDR458C_MUCL30388 | rna-NM_001180766.1_MUCL30388 | cds-NP_010746.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1305750-1307741:- | gene-YDR458C_MUCL39482 | rna-NM_001180766.1_MUCL39482 | cds-NP_010746.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1248550-1250541:- | gene-YDR458C_MUCL42920 | rna-NM_001180766.1_MUCL42920 | cds-NP_010746.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1379978-1381969:- | gene-YDR458C_NCIM3186 | rna-NM_001180766.1_NCIM3186 | cds-NP_010746.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1319522-1321513:- | gene-YDR458C_NCYC1407 | rna-NM_001180766.1_NCYC1407 | cds-NP_010746.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1330377-1332368:- | gene-YDR458C_PE2H3 | rna-NM_001180766.1_PE2H3 | cds-NP_010746.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1335934-1337925:- | gene-YDR458C_PE2H4 | rna-NM_001180766.1_PE2H4 | cds-NP_010746.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1380055-1382046:- | gene-YDR458C_S288C | rna-NM_001180766.1_S288C | cds-NP_010746.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:235118-237109:+ | gene-YDR458C_SA1 | rna-NM_001180766.1_SA1 | cds-NP_010746.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1331090-1333081:- | gene-YDR458C_ThermosaccDry | rna-NM_001180766.1_ThermosaccDry | cds-NP_010746.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1346828-1348819:- | gene-YDR458C_VR1 | rna-NM_001180766.1_VR1 | cds-NP_010746.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:373765-375756:- | gene-YDR458C_ZTW1 | rna-NM_001180766.1_ZTW1 | cds-NP_010746.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1334165-1336156:- | gene-YDR458C_Sparadoxus | rna-NM_001180766.1_Sparadoxus | cds-NP_010746.1_Sparadoxus | 84.8 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |