Gene name: HEF3
Reference locus (S288C): YNL014W
Gene biotype: protein_coding
Description: Translational elongation factor EF-3; member of the ABC superfamily; stimulates EF-1 alpha-dependent binding of aminoacyl-tRNA by the ribosome; normally expressed in zinc deficient cells; HEF3 has a paralog, YEF3, that arose from the whole genome duplication
Top 10 interactors (score): SUI2 (0.892); UTP4 (0.882); YDR061W (0.875); GCN2 (0.776); NEW1 (0.772); UTP7 (0.755); TOP2 (0.751); YEF3 (0.748); EFT1 (0.725); EFT2 (0.725); CEF1 (0.702); PWP2 (0.7); PSA1 (0.698); SDA1 (0.695); DIP2 (0.688); BAS1 (0.685); NSI1 (0.683); REB1 (0.683); NOG1 (0.683); RRP5 (0.678)
Homologues (species, bitscore): ABCF2 (Homo sapiens, 195.7); Abcf1 (Mus musculus, 197.6); abcf1 (Danio rerio, 200.7); abcf3 (Xenopus tropicalis, 188.7); CG9330 (Drosophila melanogaster, 206.5); abcf-1 (Caenorhabditis elegans, 198.7); ABCF3 (Arabidopsis thaliana, 199.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:589325-592459:+ | gene-YNL014W_AKU4011 | rna-NM_001182853.3_AKU4011 | cds-NP_014384.3_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:491772-494906:+ | gene-YNL014W_BG1 | rna-NM_001182853.3_BG1 | cds-NP_014384.3_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:606203-609337:+ | gene-YNL014W_Bruggeman | rna-NM_001182853.3_Bruggeman | cds-NP_014384.3_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:641565-644699:+ | gene-YNL014W_CAT1 | rna-NM_001182853.3_CAT1 | cds-NP_014384.3_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:595021-598155:+ | gene-YNL014W_CBS1585 | rna-NM_001182853.3_CBS1585 | cds-NP_014384.3_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:657075-660209:+ | gene-YNL014W_CBS436 | rna-NM_001182853.3_CBS436 | cds-NP_014384.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:584829-587963:+ | gene-YNL014W_CBS6412 | rna-NM_001182853.3_CBS6412 | cds-NP_014384.3_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:585993-589127:+ | gene-YNL014W_CBS6413 | rna-NM_001182853.3_CBS6413 | cds-NP_014384.3_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:599969-603103:+ | gene-YNL014W_CENPK1137D | rna-NM_001182853.3_CENPK1137D | cds-NP_014384.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:591391-594525:+ | gene-YNL014W_EthanolRed | rna-NM_001182853.3_EthanolRed | cds-NP_014384.3_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:582160-585294:+ | gene-YNL014W_FaliES1 | rna-NM_001182853.3_FaliES1 | cds-NP_014384.3_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000008.1:22667-25801:- | gene-YNL014W_JAY291 | rna-NM_001182853.3_JAY291 | cds-NP_014384.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:604292-607426:+ | gene-YNL014W_MUCL30387 | rna-NM_001182853.3_MUCL30387 | cds-NP_014384.3_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:601357-604491:- | gene-YNL014W_MUCL30388 | rna-NM_001182853.3_MUCL30388 | cds-NP_014384.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:586530-589664:+ | gene-YNL014W_MUCL39482 | rna-NM_001182853.3_MUCL39482 | cds-NP_014384.3_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:590386-593520:+ | gene-YNL014W_MUCL42920 | rna-NM_001182853.3_MUCL42920 | cds-NP_014384.3_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:606288-609422:+ | gene-YNL014W_NCIM3186 | rna-NM_001182853.3_NCIM3186 | cds-NP_014384.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:588783-591917:+ | gene-YNL014W_NCYC1407 | rna-NM_001182853.3_NCYC1407 | cds-NP_014384.3_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:590764-593898:+ | gene-YNL014W_PE2H3 | rna-NM_001182853.3_PE2H3 | cds-NP_014384.3_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:592082-595216:+ | gene-YNL014W_PE2H4 | rna-NM_001182853.3_PE2H4 | cds-NP_014384.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:606319-609453:+ | gene-YNL014W_S288C | rna-NM_001182853.3_S288C | cds-NP_014384.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000068.1:3989-7123:+ | gene-YNL014W_SA1 | rna-NM_001182853.3_SA1 | cds-NP_014384.3_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:582500-585634:+ | gene-YNL014W_ThermosaccDry | rna-NM_001182853.3_ThermosaccDry | cds-NP_014384.3_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:625109-628243:+ | gene-YNL014W_VR1 | rna-NM_001182853.3_VR1 | cds-NP_014384.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:491380-494512:+ | gene-YNL014W_ZTW1 | rna-NM_001182853.3_ZTW1 | cds-NP_014384.3_ZTW1 | 99.6 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:597541-600684:+ | gene-YNL014W_Sparadoxus | rna-NM_001182853.3_Sparadoxus | cds-NP_014384.3_Sparadoxus | 90.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |