Gene name: HCS1
Reference locus (S288C): YKL017C
Gene biotype: protein_coding
Description: Hexameric DNA polymerase alpha-associated DNA helicase A; involved in lagging strand DNA synthesis; contains single-stranded DNA stimulated ATPase and dATPase activities; replication protein A stimulates helicase and ATPase activities
Top 10 interactors (score): TAF14 (0.912); INO80 (0.906); NHP10 (0.903); IES4 (0.9); IES1 (0.9); IES3 (0.9); ARP5 (0.9); GAS1 (0.879); RVB2 (0.866); RVB1 (0.781); YLL058W (0.75); IES2 (0.723); ARP8 (0.722); ARP4 (0.722); IES6 (0.72); ACT1 (0.72); IES5 (0.72); CBS1 (0.696); RRM3 (0.681); PIF1 (0.679)
Homologues (species, bitscore): IGHMBP2 (Homo sapiens, 378.6); Ighmbp2 (Mus musculus, 359.0); ighmbp2 (Danio rerio, 372.1); ighmbp2 (Xenopus tropicalis, 352.8); Upf1 (Drosophila melanogaster, 195.3); smg-2 (Caenorhabditis elegans, 194.1); AT2G03270 (Arabidopsis thaliana, 352.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:391207-393258:- | gene-YKL017C_AKU4011 | rna-NM_001179583.1_AKU4011 | cds-NP_012908.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:250646-252697:+ | gene-YKL017C_BG1 | rna-NM_001179583.1_BG1 | cds-NP_012908.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:412910-414961:- | gene-YKL017C_Bruggeman | rna-NM_001179583.1_Bruggeman | cds-NP_012908.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:408018-410069:- | gene-YKL017C_CAT1 | rna-NM_001179583.1_CAT1 | cds-NP_012908.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:403927-405978:- | gene-YKL017C_CBS1585 | rna-NM_001179583.1_CBS1585 | cds-NP_012908.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:402788-404839:- | gene-YKL017C_CBS436 | rna-NM_001179583.1_CBS436 | cds-NP_012908.1_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:388083-390134:- | gene-YKL017C_CBS6412 | rna-NM_001179583.1_CBS6412 | cds-NP_012908.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:403782-405833:- | gene-YKL017C_CBS6413 | rna-NM_001179583.1_CBS6413 | cds-NP_012908.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:404867-406918:- | gene-YKL017C_CENPK1137D | rna-NM_001179583.1_CENPK1137D | cds-NP_012908.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:401704-403755:- | gene-YKL017C_EthanolRed | rna-NM_001179583.1_EthanolRed | cds-NP_012908.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:403794-405845:- | gene-YKL017C_FaliES1 | rna-NM_001179583.1_FaliES1 | cds-NP_012908.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000142.1:25205-27256:+ | gene-YKL017C_JAY291 | rna-NM_001179583.1_JAY291 | cds-NP_012908.1_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:412225-414276:- | gene-YKL017C_MUCL30387 | rna-NM_001179583.1_MUCL30387 | cds-NP_012908.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:407834-409885:- | gene-YKL017C_MUCL30388 | rna-NM_001179583.1_MUCL30388 | cds-NP_012908.1_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:403244-405295:- | gene-YKL017C_MUCL39482 | rna-NM_001179583.1_MUCL39482 | cds-NP_012908.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:409071-411122:- | gene-YKL017C_MUCL42920 | rna-NM_001179583.1_MUCL42920 | cds-NP_012908.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:405179-407230:- | gene-YKL017C_NCIM3186 | rna-NM_001179583.1_NCIM3186 | cds-NP_012908.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:403436-405487:- | gene-YKL017C_NCYC1407 | rna-NM_001179583.1_NCYC1407 | cds-NP_012908.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:428126-430177:- | gene-YKL017C_PE2H3 | rna-NM_001179583.1_PE2H3 | cds-NP_012908.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:412870-414921:- | gene-YKL017C_PE2H4 | rna-NM_001179583.1_PE2H4 | cds-NP_012908.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:405190-407241:- | gene-YKL017C_S288C | rna-NM_001179583.1_S288C | cds-NP_012908.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000027.1:83468-85519:- | gene-YKL017C_SA1 | rna-NM_001179583.1_SA1 | cds-NP_012908.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:403893-405944:- | gene-YKL017C_ThermosaccDry | rna-NM_001179583.1_ThermosaccDry | cds-NP_012908.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:403147-405198:- | gene-YKL017C_VR1 | rna-NM_001179583.1_VR1 | cds-NP_012908.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:401921-403972:- | gene-YKL017C_ZTW1 | rna-NM_001179583.1_ZTW1 | cds-NP_012908.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:426908-428959:- | gene-YKL017C_Sparadoxus | rna-NM_001179583.1_Sparadoxus | cds-NP_012908.1_Sparadoxus | 90.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |