Gene name: HCR1
Reference locus (S288C): YLR192C
Gene biotype: protein_coding
Description: eIF3j component of translation initiation factor 3 (eIF3); dual function protein involved in translation initiation as a substoichiometric component (eIF3j) of eIF3; required for 20S pre-rRNA processing; required at post-transcriptional step for efficient retrotransposition; absence decreases Ty1 Gag:GFP protein levels; binds eIF3 subunits Rpg1p, Prt1p and 18S rRNA; eIF3 also involved in programmed stop codon read through; human homolog EIF3J can complement yeast hcr1 mutant; Belongs to the eIF-3 subunit J family
Top 10 interactors (score): TIF34 (0.999); NIP1 (0.999); PRT1 (0.999); RPG1 (0.999); RLI1 (0.999); TIF35 (0.999); SUI1 (0.997); TIF5 (0.992); RPS20 (0.987); RPS0A (0.982); TIF11 (0.979); RPS2 (0.978); RPS15 (0.97); RPS13 (0.97); RPS23A (0.97); SUI2 (0.969); RPS12 (0.969); RPS5 (0.969); RPS18B (0.968); RPS11B (0.966)
Homologues (species, bitscore): EIF3J (Homo sapiens, 55.1); Eif3j1 (Mus musculus, 50.8); eif3ja (Danio rerio, 57.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:492911-493708:- | gene-YLR192C_AKU4011 | rna-NM_001182079.1_AKU4011 | cds-NP_013293.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000177.1:50093-50890:- | gene-YLR192C_BG1 | rna-NM_001182079.1_BG1 | cds-NP_013293.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:533162-533959:- | gene-YLR192C_Bruggeman | rna-NM_001182079.1_Bruggeman | cds-NP_013293.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:532756-533553:- | gene-YLR192C_CAT1 | rna-NM_001182079.1_CAT1 | cds-NP_013293.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:528408-529205:- | gene-YLR192C_CBS1585 | rna-NM_001182079.1_CBS1585 | cds-NP_013293.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:518548-519345:- | gene-YLR192C_CBS436 | rna-NM_001182079.1_CBS436 | cds-NP_013293.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:496965-497762:- | gene-YLR192C_CBS6412 | rna-NM_001182079.1_CBS6412 | cds-NP_013293.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:528700-529497:- | gene-YLR192C_CBS6413 | rna-NM_001182079.1_CBS6413 | cds-NP_013293.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:523440-524237:- | gene-YLR192C_CENPK1137D | rna-NM_001182079.1_CENPK1137D | cds-NP_013293.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:492439-493236:- | gene-YLR192C_EthanolRed | rna-NM_001182079.1_EthanolRed | cds-NP_013293.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:521366-522163:- | gene-YLR192C_FaliES1 | rna-NM_001182079.1_FaliES1 | cds-NP_013293.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000004.1:48265-49062:- | gene-YLR192C_JAY291 | rna-NM_001182079.1_JAY291 | cds-NP_013293.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:533181-533978:- | gene-YLR192C_MUCL30387 | rna-NM_001182079.1_MUCL30387 | cds-NP_013293.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:538114-538911:- | gene-YLR192C_MUCL30388 | rna-NM_001182079.1_MUCL30388 | cds-NP_013293.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:529389-530186:- | gene-YLR192C_MUCL39482 | rna-NM_001182079.1_MUCL39482 | cds-NP_013293.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:529885-530682:- | gene-YLR192C_MUCL42920 | rna-NM_001182079.1_MUCL42920 | cds-NP_013293.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:538766-539563:- | gene-YLR192C_NCIM3186 | rna-NM_001182079.1_NCIM3186 | cds-NP_013293.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:521817-522614:- | gene-YLR192C_NCYC1407 | rna-NM_001182079.1_NCYC1407 | cds-NP_013293.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:526054-526851:- | gene-YLR192C_PE2H3 | rna-NM_001182079.1_PE2H3 | cds-NP_013293.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:525798-526595:- | gene-YLR192C_PE2H4 | rna-NM_001182079.1_PE2H4 | cds-NP_013293.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:538792-539589:- | gene-YLR192C_S288C | rna-NM_001182079.1_S288C | cds-NP_013293.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000042.1:48323-49120:- | gene-YLR192C_SA1 | rna-NM_001182079.1_SA1 | cds-NP_013293.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:523869-524666:- | gene-YLR192C_ThermosaccDry | rna-NM_001182079.1_ThermosaccDry | cds-NP_013293.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:535167-535964:- | gene-YLR192C_VR1 | rna-NM_001182079.1_VR1 | cds-NP_013293.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000024.1:48158-48955:- | gene-YLR192C_ZTW1 | rna-NM_001182079.1_ZTW1 | cds-NP_013293.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:509922-510719:- | gene-YLR192C_Sparadoxus | rna-NM_001182079.1_Sparadoxus | cds-NP_013293.1_Sparadoxus | 91.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |