Gene name: HBS1
Reference locus (S288C): YKR084C
Gene biotype: protein_coding
Description: Elongation factor 1 alpha-like protein; GTPase with similarity to translation release factors; together with binding partner Dom34p, facilitates ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled, particularly in 3' UTRs; genetically implicated in mRNA no-go decay; HBS1 has a paralog, SKI7, that arose from the whole genome duplication
Top 10 interactors (score): DOM34 (0.999); SUP45 (0.982); ASC1 (0.982); CAM1 (0.982); RPS23A (0.979); RLI1 (0.975); EFB1 (0.958); RPS3 (0.957); RQC2 (0.952); RPS20 (0.951); RKR1 (0.947); RPS12 (0.945); RPS5 (0.944); RPL3 (0.936); RPL5 (0.931); RQC1 (0.923); RPS30B (0.922); RPS6B (0.921); RPS15 (0.918); NAM7 (0.916)
Homologues (species, bitscore): HBS1L (Homo sapiens, 304.7); Hbs1l (Mus musculus, 300.1); hbs1l (Danio rerio, 300.1); hbs1l (Xenopus tropicalis, 300.8); HBS1 (Drosophila melanogaster, 272.7); K07A12.4 (Caenorhabditis elegans, 273.5); AT5G10630 (Arabidopsis thaliana, 280.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:583086-584921:- | gene-YKR084C_AKU4011 | rna-NM_001179874.3_AKU4011 | cds-NP_013010.3_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:59304-61139:+ | gene-YKR084C_BG1 | rna-NM_001179874.3_BG1 | cds-NP_013010.3_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:605664-607499:- | gene-YKR084C_Bruggeman | rna-NM_001179874.3_Bruggeman | cds-NP_013010.3_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:601585-603420:- | gene-YKR084C_CAT1 | rna-NM_001179874.3_CAT1 | cds-NP_013010.3_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:595573-597408:- | gene-YKR084C_CBS1585 | rna-NM_001179874.3_CBS1585 | cds-NP_013010.3_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:593958-595793:- | gene-YKR084C_CBS436 | rna-NM_001179874.3_CBS436 | cds-NP_013010.3_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:578861-580696:- | gene-YKR084C_CBS6412 | rna-NM_001179874.3_CBS6412 | cds-NP_013010.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:595391-597226:- | gene-YKR084C_CBS6413 | rna-NM_001179874.3_CBS6413 | cds-NP_013010.3_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:596710-598545:- | gene-YKR084C_CENPK1137D | rna-NM_001179874.3_CENPK1137D | cds-NP_013010.3_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:592897-594732:- | gene-YKR084C_EthanolRed | rna-NM_001179874.3_EthanolRed | cds-NP_013010.3_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:596792-598627:- | gene-YKR084C_FaliES1 | rna-NM_001179874.3_FaliES1 | cds-NP_013010.3_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000426.1:46306-48141:+ | gene-YKR084C_JAY291 | rna-NM_001179874.3_JAY291 | cds-NP_013010.3_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:605159-606994:- | gene-YKR084C_MUCL30387 | rna-NM_001179874.3_MUCL30387 | cds-NP_013010.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:599503-601338:- | gene-YKR084C_MUCL30388 | rna-NM_001179874.3_MUCL30388 | cds-NP_013010.3_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:594414-596249:- | gene-YKR084C_MUCL39482 | rna-NM_001179874.3_MUCL39482 | cds-NP_013010.3_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:600437-602272:- | gene-YKR084C_MUCL42920 | rna-NM_001179874.3_MUCL42920 | cds-NP_013010.3_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:597044-598879:- | gene-YKR084C_NCIM3186 | rna-NM_001179874.3_NCIM3186 | cds-NP_013010.3_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:594826-596661:- | gene-YKR084C_NCYC1407 | rna-NM_001179874.3_NCYC1407 | cds-NP_013010.3_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:620031-621866:- | gene-YKR084C_PE2H3 | rna-NM_001179874.3_PE2H3 | cds-NP_013010.3_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:604435-606270:- | gene-YKR084C_PE2H4 | rna-NM_001179874.3_PE2H4 | cds-NP_013010.3_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:597055-598890:- | gene-YKR084C_S288C | rna-NM_001179874.3_S288C | cds-NP_013010.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000029.1:82959-84794:+ | gene-YKR084C_SA1 | rna-NM_001179874.3_SA1 | cds-NP_013010.3_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:596039-597874:- | gene-YKR084C_ThermosaccDry | rna-NM_001179874.3_ThermosaccDry | cds-NP_013010.3_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:595302-597137:- | gene-YKR084C_VR1 | rna-NM_001179874.3_VR1 | cds-NP_013010.3_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:593020-594855:- | gene-YKR084C_ZTW1 | rna-NM_001179874.3_ZTW1 | cds-NP_013010.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:618265-620100:- | gene-YKR084C_Sparadoxus | rna-NM_001179874.3_Sparadoxus | cds-NP_013010.3_Sparadoxus | 89.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |