HAP4 (YKL109W)


Gene profile

Gene name: HAP4
Reference locus (S288C): YKL109W
Gene biotype: protein_coding

Description: Transcriptional activator HAP4; Transcription factor; subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; provides the principal activation function of the complex; involved in diauxic shift

Top 10 interactors (score): HAP5 (0.999); HAP2 (0.986); HAP3 (0.962); GCN4 (0.82); MDH1 (0.797); GUT2 (0.792); ROX1 (0.782); LPD1 (0.78); CAT8 (0.765); MIG1 (0.764); ADR1 (0.745); SOK2 (0.712); SIP4 (0.711); MSN4 (0.71); SNF1 (0.691); MSN2 (0.677); ABF1 (0.675); GCR2 (0.674); RAP1 (0.674); YAP6 (0.671)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:218793-220451:+ gene-YKL109W_AKU4011 rna-NM_001179675.1_AKU4011 cds-NP_012813.1_AKU4011 99.0 99.6 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000030.1:195918-197579:+ gene-YKL109W_BG1 rna-NM_001179675.1_BG1 cds-NP_012813.1_BG1 99.5 99.8 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:236717-238377:+ gene-YKL109W_Bruggeman rna-NM_001179675.1_Bruggeman cds-NP_012813.1_Bruggeman 99.5 99.7 Unannotated 1 1 0 False False False True False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:231764-233425:+ gene-YKL109W_CAT1 rna-NM_001179675.1_CAT1 cds-NP_012813.1_CAT1 99.5 99.8 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:231022-232680:+ gene-YKL109W_CBS1585 rna-NM_001179675.1_CBS1585 cds-NP_012813.1_CBS1585 99.2 99.6 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:229612-231273:+ gene-YKL109W_CBS436 rna-NM_001179675.1_CBS436 cds-NP_012813.1_CBS436 99.2 99.8 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:215654-217312:+ gene-YKL109W_CBS6412 rna-NM_001179675.1_CBS6412 cds-NP_012813.1_CBS6412 99.2 99.6 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:231489-233147:+ gene-YKL109W_CBS6413 rna-NM_001179675.1_CBS6413 cds-NP_012813.1_CBS6413 99.0 99.6 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:231869-233533:+ gene-YKL109W_CENPK1137D rna-NM_001179675.1_CENPK1137D cds-NP_012813.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:229473-231128:+ gene-YKL109W_EthanolRed rna-NM_001179675.1_EthanolRed cds-NP_012813.1_EthanolRed 97.5 98.9 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:230286-231941:+ gene-YKL109W_FaliES1 rna-NM_001179675.1_FaliES1 cds-NP_012813.1_FaliES1 97.5 98.9 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000357.1:52633-54294:+ gene-YKL109W_JAY291 rna-NM_001179675.1_JAY291 cds-NP_012813.1_JAY291 99.5 99.8 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:238519-240180:+ gene-YKL109W_MUCL30387 rna-NM_001179675.1_MUCL30387 cds-NP_012813.1_MUCL30387 99.1 99.8 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:232898-234562:+ gene-YKL109W_MUCL30388 rna-NM_001179675.1_MUCL30388 cds-NP_012813.1_MUCL30388 99.2 99.8 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:230820-232478:+ gene-YKL109W_MUCL39482 rna-NM_001179675.1_MUCL39482 cds-NP_012813.1_MUCL39482 99.0 99.6 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:235195-236856:+ gene-YKL109W_MUCL42920 rna-NM_001179675.1_MUCL42920 cds-NP_012813.1_MUCL42920 99.5 99.8 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:232216-233880:+ gene-YKL109W_NCIM3186 rna-NM_001179675.1_NCIM3186 cds-NP_012813.1_NCIM3186 95.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:231010-232671:+ gene-YKL109W_NCYC1407 rna-NM_001179675.1_NCYC1407 cds-NP_012813.1_NCYC1407 99.3 99.8 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:238105-239766:+ gene-YKL109W_PE2H3 rna-NM_001179675.1_PE2H3 cds-NP_012813.1_PE2H3 99.5 99.8 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:234393-236054:+ gene-YKL109W_PE2H4 rna-NM_001179675.1_PE2H4 cds-NP_012813.1_PE2H4 99.5 99.8 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:232227-233891:+ gene-YKL109W_S288C rna-NM_001179675.1_S288C cds-NP_012813.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000008.1:148353-150014:+ gene-YKL109W_SA1 rna-NM_001179675.1_SA1 cds-NP_012813.1_SA1 99.5 99.8 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:230986-232641:+ gene-YKL109W_ThermosaccDry rna-NM_001179675.1_ThermosaccDry cds-NP_012813.1_ThermosaccDry 97.5 98.9 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:230365-232026:+ gene-YKL109W_VR1 rna-NM_001179675.1_VR1 cds-NP_012813.1_VR1 99.5 99.8 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:229554-231215:+ gene-YKL109W_ZTW1 rna-NM_001179675.1_ZTW1 cds-NP_012813.1_ZTW1 99.5 99.8 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:246545-248206:+ gene-YKL109W_Sparadoxus rna-NM_001179675.1_Sparadoxus cds-NP_012813.1_Sparadoxus 87.5 98.6 Verified 1 1 1 False True False False False

Additional files