HAP3 (YBL021C)


Gene profile

Gene name: HAP3
Reference locus (S288C): YBL021C
Gene biotype: protein_coding

Description: Transcriptional activator HAP3; Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex; complex is heme-activated and glucose-repressed; complex is a transcriptional activator and global regulator of respiratory gene expression; contains sequences contributing to both complex assembly and DNA binding

Top 10 interactors (score): HAP2 (0.999); HAP5 (0.999); ARP1 (0.965); HAP4 (0.962); PRP31 (0.962); DPB3 (0.889); DLS1 (0.889); BUR6 (0.864); MTH1 (0.754); NCB2 (0.744); TOS4 (0.677); CMR1 (0.677); RFA1 (0.673); PUF3 (0.669); YML096W (0.667); SUP45 (0.64); ASF1 (0.639); SPT15 (0.606); TAF7 (0.6); HCM1 (0.588)

Homologues (species, bitscore): NFYB (Homo sapiens, 143.7); Nfyb (Mus musculus, 143.7); nfybb (Danio rerio, 141.4); nfyb (Xenopus tropicalis, 142.5); Nf-YB (Drosophila melanogaster, 126.3); nfyb-1 (Caenorhabditis elegans, 122.1); NF-YB3 (Arabidopsis thaliana, 144.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:175270-175704:- gene-YBL021C_AKU4011 rna-NM_001178261.1_AKU4011 cds-NP_009532.1_AKU4011 99.5 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000179.1:166098-166532:- gene-YBL021C_BG1 rna-NM_001178261.1_BG1 cds-NP_009532.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:175856-176290:- gene-YBL021C_Bruggeman rna-NM_001178261.1_Bruggeman cds-NP_009532.1_Bruggeman 99.5 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:178467-178901:- gene-YBL021C_CAT1 rna-NM_001178261.1_CAT1 cds-NP_009532.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:167825-168259:- gene-YBL021C_CBS1585 rna-NM_001178261.1_CBS1585 cds-NP_009532.1_CBS1585 99.5 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:176280-176714:- gene-YBL021C_CBS436 rna-NM_001178261.1_CBS436 cds-NP_009532.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:266604-267038:- gene-YBL021C_CBS6412 rna-NM_001178261.1_CBS6412 cds-NP_009532.1_CBS6412 99.5 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:173395-173829:- gene-YBL021C_CBS6413 rna-NM_001178261.1_CBS6413 cds-NP_009532.1_CBS6413 99.5 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:175425-175859:- gene-YBL021C_CENPK1137D rna-NM_001178261.1_CENPK1137D cds-NP_009532.1_CENPK1137D 99.7 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:302812-303246:- gene-YBL021C_EthanolRed rna-NM_001178261.1_EthanolRed cds-NP_009532.1_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:190078-190512:- gene-YBL021C_FaliES1 rna-NM_001178261.1_FaliES1 cds-NP_009532.1_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000421.1:15749-16183:- gene-YBL021C_JAY291 rna-NM_001178261.1_JAY291 cds-NP_009532.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:175713-176147:- gene-YBL021C_MUCL30387 rna-NM_001178261.1_MUCL30387 cds-NP_009532.1_MUCL30387 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:176755-177189:- gene-YBL021C_MUCL30388 rna-NM_001178261.1_MUCL30388 cds-NP_009532.1_MUCL30388 99.5 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:168010-168444:- gene-YBL021C_MUCL39482 rna-NM_001178261.1_MUCL39482 cds-NP_009532.1_MUCL39482 99.5 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:175285-175719:- gene-YBL021C_MUCL42920 rna-NM_001178261.1_MUCL42920 cds-NP_009532.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:181457-181891:- gene-YBL021C_NCIM3186 rna-NM_001178261.1_NCIM3186 cds-NP_009532.1_NCIM3186 99.5 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:169159-169593:- gene-YBL021C_NCYC1407 rna-NM_001178261.1_NCYC1407 cds-NP_009532.1_NCYC1407 99.5 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:175386-175820:- gene-YBL021C_PE2H3 rna-NM_001178261.1_PE2H3 cds-NP_009532.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:173030-173464:- gene-YBL021C_PE2H4 rna-NM_001178261.1_PE2H4 cds-NP_009532.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:181660-182094:- gene-YBL021C_S288C rna-NM_001178261.1_S288C cds-NP_009532.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000051.1:66381-66815:- gene-YBL021C_SA1 rna-NM_001178261.1_SA1 cds-NP_009532.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:190033-190467:- gene-YBL021C_ThermosaccDry rna-NM_001178261.1_ThermosaccDry cds-NP_009532.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:172199-172633:- gene-YBL021C_VR1 rna-NM_001178261.1_VR1 cds-NP_009532.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:166745-167179:- gene-YBL021C_ZTW1 rna-NM_001178261.1_ZTW1 cds-NP_009532.1_ZTW1 99.7 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:201682-202116:- gene-YBL021C_Sparadoxus rna-NM_001178261.1_Sparadoxus cds-NP_009532.1_Sparadoxus 92.6 100.0 Verified 1 1 1 False True False False False

Additional files