Gene name: HAP2
Reference locus (S288C): YGL237C
Gene biotype: protein_coding
Description: Nuclear transcription factor y, alpha; Transcriptional activator HAP2; Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex; complex is heme-activated and glucose-repressed; complex is a transcriptional activator and global regulator of respiratory gene expression; contains sequences sufficient for both complex assembly and DNA binding; respiratory defect of the null mutant is functionally complemented by human NFYA
Top 10 interactors (score): HAP5 (0.999); HAP3 (0.999); HAP4 (0.986); DLS1 (0.905); DPB3 (0.905); MTH1 (0.777); CSE4 (0.776); HAP1 (0.753); HHT2 (0.753); HHF1 (0.729); YAP5 (0.723); DAL81 (0.719); RDS1 (0.711); GRX3 (0.709); STP1 (0.703); HHT1 (0.698); HHF2 (0.698); STD1 (0.694); TFA1 (0.692); SHY1 (0.658)
Homologues (species, bitscore): NFYA (Homo sapiens, 99.8); Nfya (Mus musculus, 99.8); nfyal (Danio rerio, 99.0); nfya (Xenopus tropicalis, 96.3); Nf-YA (Drosophila melanogaster, 101.3); nfya-2 (Caenorhabditis elegans, 67.8); NF-YA1 (Arabidopsis thaliana, 91.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:54264-55061:- | gene-YGL237C_AKU4011 | rna-NM_001181103.1_AKU4011 | cds-NP_011277.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000175.1:46296-47096:- | gene-YGL237C_BG1 | rna-NM_001181103.1_BG1 | cds-NP_011277.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:54611-55417:- | gene-YGL237C_Bruggeman | rna-NM_001181103.1_Bruggeman | cds-NP_011277.1_Bruggeman | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:52683-53483:- | gene-YGL237C_CAT1 | rna-NM_001181103.1_CAT1 | cds-NP_011277.1_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:58552-59349:- | gene-YGL237C_CBS1585 | rna-NM_001181103.1_CBS1585 | cds-NP_011277.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:53268-54068:- | gene-YGL237C_CBS436 | rna-NM_001181103.1_CBS436 | cds-NP_011277.1_CBS436 | 98.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:46121-46918:- | gene-YGL237C_CBS6412 | rna-NM_001181103.1_CBS6412 | cds-NP_011277.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:52409-53209:- | gene-YGL237C_CBS6413 | rna-NM_001181103.1_CBS6413 | cds-NP_011277.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:52387-53205:- | gene-YGL237C_CENPK1137D | rna-NM_001181103.1_CENPK1137D | cds-NP_011277.1_CENPK1137D | 96.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:45352-46149:- | gene-YGL237C_EthanolRed | rna-NM_001181103.1_EthanolRed | cds-NP_011277.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:45937-46734:- | gene-YGL237C_FaliES1 | rna-NM_001181103.1_FaliES1 | cds-NP_011277.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000079.1:20392-21192:+ | gene-YGL237C_JAY291 | rna-NM_001181103.1_JAY291 | cds-NP_011277.1_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:54544-55344:- | gene-YGL237C_MUCL30387 | rna-NM_001181103.1_MUCL30387 | cds-NP_011277.1_MUCL30387 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:56701-57507:- | gene-YGL237C_MUCL30388 | rna-NM_001181103.1_MUCL30388 | cds-NP_011277.1_MUCL30388 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:55149-55946:- | gene-YGL237C_MUCL39482 | rna-NM_001181103.1_MUCL39482 | cds-NP_011277.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:58029-58829:- | gene-YGL237C_MUCL42920 | rna-NM_001181103.1_MUCL42920 | cds-NP_011277.1_MUCL42920 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:52731-53528:- | gene-YGL237C_NCIM3186 | rna-NM_001181103.1_NCIM3186 | cds-NP_011277.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:46909-47706:- | gene-YGL237C_NCYC1407 | rna-NM_001181103.1_NCYC1407 | cds-NP_011277.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:48762-49562:- | gene-YGL237C_PE2H3 | rna-NM_001181103.1_PE2H3 | cds-NP_011277.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:48310-49110:- | gene-YGL237C_PE2H4 | rna-NM_001181103.1_PE2H4 | cds-NP_011277.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:52731-53528:- | gene-YGL237C_S288C | rna-NM_001181103.1_S288C | cds-NP_011277.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:321802-322602:+ | gene-YGL237C_SA1 | rna-NM_001181103.1_SA1 | cds-NP_011277.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:46243-47040:- | gene-YGL237C_ThermosaccDry | rna-NM_001181103.1_ThermosaccDry | cds-NP_011277.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:53198-53998:- | gene-YGL237C_VR1 | rna-NM_001181103.1_VR1 | cds-NP_011277.1_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:45288-46085:- | gene-YGL237C_ZTW1 | rna-NM_001181103.1_ZTW1 | cds-NP_011277.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:53970-54731:- | gene-YGL237C_Sparadoxus | rna-NM_001181103.1_Sparadoxus | cds-NP_011277.1_Sparadoxus | 87.0 | 95.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |