Gene name: HAL5
Reference locus (S288C): YJL165C
Gene biotype: protein_coding
Description: Serine/threonine-protein kinase HAL5; Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication
Top 10 interactors (score): MEC1 (0.875); TRK1 (0.868); PPZ1 (0.857); TEL1 (0.809); TRK2 (0.762); DPB11 (0.748); SIS2 (0.745); TOF1 (0.742); CSM3 (0.711); SAT4 (0.704); CDC45 (0.698); RAD24 (0.697); RAD51 (0.679); ISR1 (0.675); ALK1 (0.663); HAL1 (0.658); RAD17 (0.637); MIH1 (0.633); ARK1 (0.613); YCH1 (0.612)
Homologues (species, bitscore): PRKAA2 (Homo sapiens, 103.6); Prkaa2 (Mus musculus, 102.8); brsk2b (Danio rerio, 100.1); prkaa2 (Xenopus tropicalis, 102.4); CG43143 (Drosophila melanogaster, 103.6); pig-1 (Caenorhabditis elegans, 101.3); SNRK2.2 (Arabidopsis thaliana, 107.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:95277-97844:- | gene-YJL165C_AKU4011 | rna-NM_001181598.1_AKU4011 | cds-NP_012370.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000186.1:7321-9888:- | gene-YJL165C_BG1 | rna-NM_001181598.1_BG1 | cds-NP_012370.1_BG1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:107106-109673:- | gene-YJL165C_Bruggeman | rna-NM_001181598.1_Bruggeman | cds-NP_012370.1_Bruggeman | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:110578-113145:- | gene-YJL165C_CAT1 | rna-NM_001181598.1_CAT1 | cds-NP_012370.1_CAT1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:100912-103479:- | gene-YJL165C_CBS1585 | rna-NM_001181598.1_CBS1585 | cds-NP_012370.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:125674-128241:- | gene-YJL165C_CBS436 | rna-NM_001181598.1_CBS436 | cds-NP_012370.1_CBS436 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:97394-99961:- | gene-YJL165C_CBS6412 | rna-NM_001181598.1_CBS6412 | cds-NP_012370.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:98387-100954:- | gene-YJL165C_CBS6413 | rna-NM_001181598.1_CBS6413 | cds-NP_012370.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:89359-91926:- | gene-YJL165C_CENPK1137D | rna-NM_001181598.1_CENPK1137D | cds-NP_012370.1_CENPK1137D | 96.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:99572-102139:- | gene-YJL165C_EthanolRed | rna-NM_001181598.1_EthanolRed | cds-NP_012370.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:104849-107407:- | gene-YJL165C_FaliES1 | rna-NM_001181598.1_FaliES1 | cds-NP_012370.1_FaliES1 | 99.4 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000164.1:11308-13875:+ | gene-YJL165C_JAY291 | rna-NM_001181598.1_JAY291 | cds-NP_012370.1_JAY291 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:108834-111401:- | gene-YJL165C_MUCL30387 | rna-NM_001181598.1_MUCL30387 | cds-NP_012370.1_MUCL30387 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:105396-107963:- | gene-YJL165C_MUCL30388 | rna-NM_001181598.1_MUCL30388 | cds-NP_012370.1_MUCL30388 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:99654-102221:- | gene-YJL165C_MUCL39482 | rna-NM_001181598.1_MUCL39482 | cds-NP_012370.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:104261-106828:- | gene-YJL165C_MUCL42920 | rna-NM_001181598.1_MUCL42920 | cds-NP_012370.1_MUCL42920 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:106873-109440:- | gene-YJL165C_NCIM3186 | rna-NM_001181598.1_NCIM3186 | cds-NP_012370.1_NCIM3186 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:98265-100832:- | gene-YJL165C_NCYC1407 | rna-NM_001181598.1_NCYC1407 | cds-NP_012370.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:110980-113547:- | gene-YJL165C_PE2H3 | rna-NM_001181598.1_PE2H3 | cds-NP_012370.1_PE2H3 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:110619-113186:- | gene-YJL165C_PE2H4 | rna-NM_001181598.1_PE2H4 | cds-NP_012370.1_PE2H4 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:106894-109461:- | gene-YJL165C_S288C | rna-NM_001181598.1_S288C | cds-NP_012370.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000022.1:44086-46653:+ | gene-YJL165C_SA1 | rna-NM_001181598.1_SA1 | cds-NP_012370.1_SA1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:98042-100600:- | gene-YJL165C_ThermosaccDry | rna-NM_001181598.1_ThermosaccDry | cds-NP_012370.1_ThermosaccDry | 99.4 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:104929-107496:- | gene-YJL165C_VR1 | rna-NM_001181598.1_VR1 | cds-NP_012370.1_VR1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:85623-88130:- | gene-YJL165C_ZTW1 | rna-NM_001181598.1_ZTW1 | cds-NP_012370.1_ZTW1 | 96.6 | 97.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:110089-112653:- | gene-YJL165C_Sparadoxus | rna-NM_001181598.1_Sparadoxus | cds-NP_012370.1_Sparadoxus | 90.3 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |