Gene name: HAC1
Reference locus (S288C): YFL031W
Gene biotype: protein_coding
Description: Transcriptional activator HAC1; Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog); regulates the unfolded protein response, via UPRE binding, and membrane biogenesis; ER stress-induced splicing pathway facilitates efficient Hac1p synthesis; two functional forms of Hac1p are produced; translation initiation is repressed under non-stress conditions; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): RPL20A (0.999); IRE1 (0.972); KAR2 (0.952); PDI1 (0.924); ERO1 (0.899); TRL1 (0.895); HRD1 (0.895); INO2 (0.889); LHS1 (0.848); RPN4 (0.825); SCJ1 (0.825); OPI3 (0.821); ALG12 (0.81); OST5 (0.807); ROT2 (0.801); HRD3 (0.8); DIE2 (0.793); OPI1 (0.786); GCN4 (0.782); CHO2 (0.772)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005300.1:71533-72501:+ | gene-YFL031W_AKU4011 | rna-NM_001179935.1_AKU4011 | cds-NP_116622.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000089.1:1842-2830:+ | gene-YFL031W_BG1 | rna-NM_001179935.1_BG1 | cds-NP_116622.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005508.1:70407-71370:+ | gene-YFL031W_Bruggeman | rna-NM_001179935.1_Bruggeman | cds-NP_116622.1_Bruggeman | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005524.1:75549-76518:+ | gene-YFL031W_CAT1 | rna-NM_001179935.1_CAT1 | cds-NP_116622.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005364.1:72341-73309:+ | gene-YFL031W_CBS1585 | rna-NM_001179935.1_CBS1585 | cds-NP_116622.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005348.1:45842-46806:+ | gene-YFL031W_CBS436 | rna-NM_001179935.1_CBS436 | cds-NP_116622.1_CBS436 | 98.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005332.1:72075-73043:+ | gene-YFL031W_CBS6412 | rna-NM_001179935.1_CBS6412 | cds-NP_116622.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005316.1:74610-75578:+ | gene-YFL031W_CBS6413 | rna-NM_001179935.1_CBS6413 | cds-NP_116622.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001527.1:71506-72473:+ | gene-YFL031W_CENPK1137D | rna-NM_001179935.1_CENPK1137D | cds-NP_116622.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005476.1:70494-71462:+ | gene-YFL031W_EthanolRed | rna-NM_001179935.1_EthanolRed | cds-NP_116622.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005540.1:72133-73101:+ | gene-YFL031W_FaliES1 | rna-NM_001179935.1_FaliES1 | cds-NP_116622.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000448.1:80524-81487:+ | gene-YFL031W_JAY291 | rna-NM_001179935.1_JAY291 | cds-NP_116622.1_JAY291 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005412.1:72503-73471:+ | gene-YFL031W_MUCL30387 | rna-NM_001179935.1_MUCL30387 | cds-NP_116622.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005444.1:70399-71362:+ | gene-YFL031W_MUCL30388 | rna-NM_001179935.1_MUCL30388 | cds-NP_116622.1_MUCL30388 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005284.1:70726-71694:+ | gene-YFL031W_MUCL39482 | rna-NM_001179935.1_MUCL39482 | cds-NP_116622.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005428.1:68842-69808:+ | gene-YFL031W_MUCL42920 | rna-NM_001179935.1_MUCL42920 | cds-NP_116622.1_MUCL42920 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011815.1:75178-76146:+ | gene-YFL031W_NCIM3186 | rna-NM_001179935.1_NCIM3186 | cds-NP_116622.1_NCIM3186 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005268.1:71813-72783:+ | gene-YFL031W_NCYC1407 | rna-NM_001179935.1_NCYC1407 | cds-NP_116622.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994145.1:91708-92678:+ | gene-YFL031W_PE2H3 | rna-NM_001179935.1_PE2H3 | cds-NP_116622.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999877.1:91259-92229:+ | gene-YFL031W_PE2H4 | rna-NM_001179935.1_PE2H4 | cds-NP_116622.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001138.5:75179-76147:+ | gene-YFL031W_S288C | rna-NM_001179935.1_S288C | cds-NP_116622.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:259774-260434:- | gene-YFL031W_SA1 | rna-NM_001179935.1_SA1 | cds-NP_116622.1_SA1 | 91.4 | 92.1 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005492.1:71316-72284:+ | gene-YFL031W_ThermosaccDry | rna-NM_001179935.1_ThermosaccDry | cds-NP_116622.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005460.1:79856-80826:+ | gene-YFL031W_VR1 | rna-NM_001179935.1_VR1 | cds-NP_116622.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000013.1:1803-2765:+ | gene-YFL031W_ZTW1 | rna-NM_001179935.1_ZTW1 | cds-NP_116622.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047492.1:95573-96537:+ | gene-YFL031W_Sparadoxus | rna-NM_001179935.1_Sparadoxus | cds-NP_116622.1_Sparadoxus | 94.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |