Gene name: GYL1
Reference locus (S288C): YMR192W
Gene biotype: protein_coding
Description: Probable GTPase-activating protein GYL1; Putative GTPase activating protein (GAP) with a role in exocytosis; stimulates Gyp5p GAP activity on Ypt1p, colocalizes with Gyp5p at sites of polarized growth; interacts with Gyp5p, Rvs161p, and Rvs167p; involved in recruiting Rvs167p to the bud tip during polarized growth; increases in abundance and relocalizes from bud neck to cytoplasm upon DNA replication stress; GYL1 has a paralog, GYP5, that arose from the whole genome duplication
Top 10 interactors (score): GYP5 (0.999); RVS167 (0.974); RVS161 (0.921); SEC4 (0.884); GYP1 (0.861); YSC84 (0.858); GYP7 (0.851); DSS4 (0.811); MSB4 (0.795); GYP8 (0.788); ARF3 (0.682); LSB3 (0.674); RPL25 (0.646); GYP6 (0.635); VPS21 (0.624); YPT32 (0.622); SEC22 (0.612); SEC2 (0.608); YPT6 (0.603); BGL2 (0.598)
Homologues (species, bitscore): EVI5 (Homo sapiens, 136.0); Evi5 (Mus musculus, 135.2); evi5b (Danio rerio, 134.0); evi5l (Xenopus tropicalis, 132.5); Evi5 (Drosophila melanogaster, 120.2); tbc-4 (Caenorhabditis elegans, 121.7); PAM1 (Arabidopsis thaliana, 94.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:687034-689196:+ | gene-YMR192W_AKU4011 | rna-NM_001182698.1_AKU4011 | cds-NP_013917.1_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:265388-267550:- | gene-YMR192W_BG1 | rna-NM_001182698.1_BG1 | cds-NP_013917.1_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:631265-633427:+ | gene-YMR192W_Bruggeman | rna-NM_001182698.1_Bruggeman | cds-NP_013917.1_Bruggeman | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:634511-636673:+ | gene-YMR192W_CAT1 | rna-NM_001182698.1_CAT1 | cds-NP_013917.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:619290-621452:+ | gene-YMR192W_CBS1585 | rna-NM_001182698.1_CBS1585 | cds-NP_013917.1_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:623558-625720:+ | gene-YMR192W_CBS436 | rna-NM_001182698.1_CBS436 | cds-NP_013917.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:730849-733011:+ | gene-YMR192W_CBS6412 | rna-NM_001182698.1_CBS6412 | cds-NP_013917.1_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:618441-620603:+ | gene-YMR192W_CBS6413 | rna-NM_001182698.1_CBS6413 | cds-NP_013917.1_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:641807-643969:+ | gene-YMR192W_CENPK1137D | rna-NM_001182698.1_CENPK1137D | cds-NP_013917.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:679481-681643:+ | gene-YMR192W_EthanolRed | rna-NM_001182698.1_EthanolRed | cds-NP_013917.1_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:625137-627299:+ | gene-YMR192W_FaliES1 | rna-NM_001182698.1_FaliES1 | cds-NP_013917.1_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000141.1:158705-160867:- | gene-YMR192W_JAY291 | rna-NM_001182698.1_JAY291 | cds-NP_013917.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:624811-626973:+ | gene-YMR192W_MUCL30387 | rna-NM_001182698.1_MUCL30387 | cds-NP_013917.1_MUCL30387 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:631591-633753:+ | gene-YMR192W_MUCL30388 | rna-NM_001182698.1_MUCL30388 | cds-NP_013917.1_MUCL30388 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:620362-622524:+ | gene-YMR192W_MUCL39482 | rna-NM_001182698.1_MUCL39482 | cds-NP_013917.1_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:627710-629872:+ | gene-YMR192W_MUCL42920 | rna-NM_001182698.1_MUCL42920 | cds-NP_013917.1_MUCL42920 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:647072-649234:+ | gene-YMR192W_NCIM3186 | rna-NM_001182698.1_NCIM3186 | cds-NP_013917.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:620014-622176:+ | gene-YMR192W_NCYC1407 | rna-NM_001182698.1_NCYC1407 | cds-NP_013917.1_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:629902-632064:+ | gene-YMR192W_PE2H3 | rna-NM_001182698.1_PE2H3 | cds-NP_013917.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:630888-633050:+ | gene-YMR192W_PE2H4 | rna-NM_001182698.1_PE2H4 | cds-NP_013917.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:647118-649280:+ | gene-YMR192W_S288C | rna-NM_001182698.1_S288C | cds-NP_013917.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:158831-160993:- | gene-YMR192W_SA1 | rna-NM_001182698.1_SA1 | cds-NP_013917.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:621263-623425:+ | gene-YMR192W_ThermosaccDry | rna-NM_001182698.1_ThermosaccDry | cds-NP_013917.1_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:634435-636597:+ | gene-YMR192W_VR1 | rna-NM_001182698.1_VR1 | cds-NP_013917.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000028.1:37050-39212:+ | gene-YMR192W_ZTW1 | rna-NM_001182698.1_ZTW1 | cds-NP_013917.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:639154-641301:+ | gene-YMR192W_Sparadoxus | rna-NM_001182698.1_Sparadoxus | cds-NP_013917.1_Sparadoxus | 85.2 | 99.1 | Verified | 1 | 1 | 1 | False | True | False | False | False |