GUS1 (YGL245W)


Gene profile

Gene name: GUS1
Reference locus (S288C): YGL245W
Gene biotype: protein_coding

Description: Glutamate--tRNA ligase, cytoplasmic; Glutamyl-tRNA synthetase (GluRS); forms a complex with methionyl-tRNA synthetase (Mes1p) and Arc1p; complex formation increases the catalytic efficiency of both tRNA synthetases and ensures their correct localization to the cytoplasm; protein abundance increases in response to DNA replication stress; Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily

Top 10 interactors (score): DPS1 (0.999); ARC1 (0.999); MES1 (0.999); KRS1 (0.999); ILS1 (0.999); CDC60 (0.999); VAS1 (0.997); GLN4 (0.995); TYS1 (0.995); DED81 (0.991); YHR020W (0.991); MSK1 (0.99); NAM2 (0.98); FRS1 (0.976); GRS1 (0.975); YDR341C (0.975); AIM10 (0.97); SES1 (0.969); THS1 (0.968); ALA1 (0.963)

Homologues (species, bitscore): EPRS (Homo sapiens, 563.5); Eprs (Mus musculus, 557.4); eprs (Danio rerio, 568.5); eprs (Xenopus tropicalis, 567.0); CG5394 (Drosophila melanogaster, 543.1); ears-1 (Caenorhabditis elegans, 513.8); AT5G26710 (Arabidopsis thaliana, 604.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:40548-42674:+ gene-YGL245W_AKU4011 rna-NM_001181111.1_AKU4011 cds-NP_011269.2_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000175.1:32587-34713:+ gene-YGL245W_BG1 rna-NM_001181111.1_BG1 cds-NP_011269.2_BG1 99.9 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:40903-43029:+ gene-YGL245W_Bruggeman rna-NM_001181111.1_Bruggeman cds-NP_011269.2_Bruggeman 99.3 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:38975-41101:+ gene-YGL245W_CAT1 rna-NM_001181111.1_CAT1 cds-NP_011269.2_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:44836-46962:+ gene-YGL245W_CBS1585 rna-NM_001181111.1_CBS1585 cds-NP_011269.2_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:39564-41690:+ gene-YGL245W_CBS436 rna-NM_001181111.1_CBS436 cds-NP_011269.2_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:32404-34530:+ gene-YGL245W_CBS6412 rna-NM_001181111.1_CBS6412 cds-NP_011269.2_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:38692-40818:+ gene-YGL245W_CBS6413 rna-NM_001181111.1_CBS6413 cds-NP_011269.2_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:38685-40811:+ gene-YGL245W_CENPK1137D rna-NM_001181111.1_CENPK1137D cds-NP_011269.2_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:31825-33951:+ gene-YGL245W_EthanolRed rna-NM_001181111.1_EthanolRed cds-NP_011269.2_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:32186-34312:+ gene-YGL245W_FaliES1 rna-NM_001181111.1_FaliES1 cds-NP_011269.2_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000079.1:32769-34895:- gene-YGL245W_JAY291 rna-NM_001181111.1_JAY291 cds-NP_011269.2_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:40840-42966:+ gene-YGL245W_MUCL30387 rna-NM_001181111.1_MUCL30387 cds-NP_011269.2_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:42993-45119:+ gene-YGL245W_MUCL30388 rna-NM_001181111.1_MUCL30388 cds-NP_011269.2_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:41433-43559:+ gene-YGL245W_MUCL39482 rna-NM_001181111.1_MUCL39482 cds-NP_011269.2_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:44326-46452:+ gene-YGL245W_MUCL42920 rna-NM_001181111.1_MUCL42920 cds-NP_011269.2_MUCL42920 99.6 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:39023-41149:+ gene-YGL245W_NCIM3186 rna-NM_001181111.1_NCIM3186 cds-NP_011269.2_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:33197-35323:+ gene-YGL245W_NCYC1407 rna-NM_001181111.1_NCYC1407 cds-NP_011269.2_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:35053-37179:+ gene-YGL245W_PE2H3 rna-NM_001181111.1_PE2H3 cds-NP_011269.2_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:34601-36727:+ gene-YGL245W_PE2H4 rna-NM_001181111.1_PE2H4 cds-NP_011269.2_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:39023-41149:+ gene-YGL245W_S288C rna-NM_001181111.1_S288C cds-NP_011269.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000002.1:334185-336311:- gene-YGL245W_SA1 rna-NM_001181111.1_SA1 cds-NP_011269.2_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:32501-34627:+ gene-YGL245W_ThermosaccDry rna-NM_001181111.1_ThermosaccDry cds-NP_011269.2_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:39490-41616:+ gene-YGL245W_VR1 rna-NM_001181111.1_VR1 cds-NP_011269.2_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000014.1:31574-33700:+ gene-YGL245W_ZTW1 rna-NM_001181111.1_ZTW1 cds-NP_011269.2_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:40268-42394:+ gene-YGL245W_Sparadoxus rna-NM_001181111.1_Sparadoxus cds-NP_011269.2_Sparadoxus 92.8 100.0 Verified 1 1 1 False True False False False

Additional files