GUP2 (YPL189W)


Gene profile

Gene name: GUP2
Reference locus (S288C): YPL189W
Gene biotype: protein_coding

Description: Glycerol uptake protein 2; Probable membrane protein; possible role in proton symport of glycerol; member of the MBOAT family of putative membrane-bound O-acyltransferases; homolog of the mammalian Hedgehog pathway modulator HHAT; GUP2 has a paralog, GUP1, that arose from the whole genome duplication

Top 10 interactors (score): LYS2 (0.831); ACP1 (0.709); MIL1 (0.7); SLM2 (0.652); ALE1 (0.639); ESC8 (0.619); AIM4 (0.613); CAB5 (0.609); HES1 (0.606); KTR4 (0.599); YBR284W (0.595); ECI1 (0.577); YDR248C (0.573); RMA1 (0.572); SOL2 (0.568); HVG1 (0.563); CAT2 (0.559); GLO4 (0.558); PRM15 (0.558); RRP8 (0.547)

Homologues (species, bitscore): HHAT (Homo sapiens, 77.4); Hhat (Mus musculus, 71.2); hhat (Danio rerio, 104.8); hhat (Xenopus tropicalis, 56.2); rasp (Drosophila melanogaster, 66.2); AT1G57600 (Arabidopsis thaliana, 250.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:166993-168822:+ gene-YPL189W_AKU4011 rna-NM_001184003.1_AKU4011 cds-NP_015135.1_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000069.1:372789-374618:+ gene-YPL189W_BG1 rna-NM_001184003.1_BG1 cds-NP_015135.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:193003-194832:+ gene-YPL189W_Bruggeman rna-NM_001184003.1_Bruggeman cds-NP_015135.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:189338-191167:+ gene-YPL189W_CAT1 rna-NM_001184003.1_CAT1 cds-NP_015135.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:171213-173042:+ gene-YPL189W_CBS1585 rna-NM_001184003.1_CBS1585 cds-NP_015135.1_CBS1585 99.1 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:185880-187709:+ gene-YPL189W_CBS436 rna-NM_001184003.1_CBS436 cds-NP_015135.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:175944-177773:+ gene-YPL189W_CBS6412 rna-NM_001184003.1_CBS6412 cds-NP_015135.1_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:167355-169184:+ gene-YPL189W_CBS6413 rna-NM_001184003.1_CBS6413 cds-NP_015135.1_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:189100-190929:+ gene-YPL189W_CENPK1137D rna-NM_001184003.1_CENPK1137D cds-NP_015135.1_CENPK1137D 99.8 99.9 Unannotated 1 1 0 False False False False True
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:166148-167977:+ gene-YPL189W_EthanolRed rna-NM_001184003.1_EthanolRed cds-NP_015135.1_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:173519-175348:+ gene-YPL189W_FaliES1 rna-NM_001184003.1_FaliES1 cds-NP_015135.1_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000007.1:190533-192362:- gene-YPL189W_JAY291 rna-NM_001184003.1_JAY291 cds-NP_015135.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:184378-186207:+ gene-YPL189W_MUCL30387 rna-NM_001184003.1_MUCL30387 cds-NP_015135.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:182522-184351:+ gene-YPL189W_MUCL30388 rna-NM_001184003.1_MUCL30388 cds-NP_015135.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:164542-166371:+ gene-YPL189W_MUCL39482 rna-NM_001184003.1_MUCL39482 cds-NP_015135.1_MUCL39482 99.1 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:221352-223181:+ gene-YPL189W_MUCL42920 rna-NM_001184003.1_MUCL42920 cds-NP_015135.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:189137-190966:+ gene-YPL189W_NCIM3186 rna-NM_001184003.1_NCIM3186 cds-NP_015135.1_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:170888-172717:+ gene-YPL189W_NCYC1407 rna-NM_001184003.1_NCYC1407 cds-NP_015135.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:178500-180329:+ gene-YPL189W_PE2H3 rna-NM_001184003.1_PE2H3 cds-NP_015135.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:178143-179972:+ gene-YPL189W_PE2H4 rna-NM_001184003.1_PE2H4 cds-NP_015135.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:189154-190983:+ gene-YPL189W_S288C rna-NM_001184003.1_S288C cds-NP_015135.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000012.1:182371-184200:- gene-YPL189W_SA1 rna-NM_001184003.1_SA1 cds-NP_015135.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:173298-175127:+ gene-YPL189W_ThermosaccDry rna-NM_001184003.1_ThermosaccDry cds-NP_015135.1_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:188274-190103:+ gene-YPL189W_VR1 rna-NM_001184003.1_VR1 cds-NP_015135.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:172610-174439:+ gene-YPL189W_ZTW1 rna-NM_001184003.1_ZTW1 cds-NP_015135.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:174244-176073:+ gene-YPL189W_Sparadoxus rna-NM_001184003.1_Sparadoxus cds-NP_015135.1_Sparadoxus 88.7 100.0 Verified 1 1 1 False True False False False

Additional files