Gene name: GUP1
Reference locus (S288C): YGL084C
Gene biotype: protein_coding
Description: Glycerol uptake protein 1; Plasma membrane protein involved in remodeling GPI anchors; member of the MBOAT family of putative membrane-bound O-acyltransferases; role in misfolded protein quality control; proposed to be involved in glycerol transport; homolog of the mammalian Hedgehog pathway modulator HHATL; GUP1 has a paralog, GUP2, that arose from the whole genome duplication
Top 10 interactors (score): ALE1 (0.917); LYS2 (0.831); CPD1 (0.813); PER1 (0.786); ACP1 (0.709); GUT1 (0.694); CST26 (0.676); FUN14 (0.65); ROT2 (0.645); GUT2 (0.641); CWH43 (0.637); BSC6 (0.618); ARE2 (0.617); DAK1 (0.616); CSF1 (0.604); LIP1 (0.595); CNE1 (0.593); GAS1 (0.581); KRE1 (0.577); SLM2 (0.572)
Homologues (species, bitscore): HHAT (Homo sapiens, 68.9); Hhat (Mus musculus, 68.9); hhat (Danio rerio, 101.7); hhatl (Xenopus tropicalis, 60.5); rasp (Drosophila melanogaster, 63.5); AT1G57600 (Arabidopsis thaliana, 256.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:353634-355316:- | gene-YGL084C_AKU4011 | rna-NM_001180949.1_AKU4011 | cds-NP_011431.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:50102-51784:+ | gene-YGL084C_BG1 | rna-NM_001180949.1_BG1 | cds-NP_011431.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:356115-357797:- | gene-YGL084C_Bruggeman | rna-NM_001180949.1_Bruggeman | cds-NP_011431.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:353017-354699:- | gene-YGL084C_CAT1 | rna-NM_001180949.1_CAT1 | cds-NP_011431.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:356959-358641:- | gene-YGL084C_CBS1585 | rna-NM_001180949.1_CBS1585 | cds-NP_011431.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:351230-352912:- | gene-YGL084C_CBS436 | rna-NM_001180949.1_CBS436 | cds-NP_011431.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:341340-343022:- | gene-YGL084C_CBS6412 | rna-NM_001180949.1_CBS6412 | cds-NP_011431.1_CBS6412 | 99.5 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:351264-352946:- | gene-YGL084C_CBS6413 | rna-NM_001180949.1_CBS6413 | cds-NP_011431.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:350805-352487:- | gene-YGL084C_CENPK1137D | rna-NM_001180949.1_CENPK1137D | cds-NP_011431.1_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:342705-344387:- | gene-YGL084C_EthanolRed | rna-NM_001180949.1_EthanolRed | cds-NP_011431.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:345266-346948:- | gene-YGL084C_FaliES1 | rna-NM_001180949.1_FaliES1 | cds-NP_011431.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000369.1:30889-32571:- | gene-YGL084C_JAY291 | rna-NM_001180949.1_JAY291 | cds-NP_011431.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:353092-354774:- | gene-YGL084C_MUCL30387 | rna-NM_001180949.1_MUCL30387 | cds-NP_011431.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:356076-357758:- | gene-YGL084C_MUCL30388 | rna-NM_001180949.1_MUCL30388 | cds-NP_011431.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:353487-355169:- | gene-YGL084C_MUCL39482 | rna-NM_001180949.1_MUCL39482 | cds-NP_011431.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:358001-359683:- | gene-YGL084C_MUCL42920 | rna-NM_001180949.1_MUCL42920 | cds-NP_011431.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:350616-352298:- | gene-YGL084C_NCIM3186 | rna-NM_001180949.1_NCIM3186 | cds-NP_011431.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:345022-346704:- | gene-YGL084C_NCYC1407 | rna-NM_001180949.1_NCYC1407 | cds-NP_011431.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:346655-348337:- | gene-YGL084C_PE2H3 | rna-NM_001180949.1_PE2H3 | cds-NP_011431.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:351640-353322:- | gene-YGL084C_PE2H4 | rna-NM_001180949.1_PE2H4 | cds-NP_011431.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:350616-352298:- | gene-YGL084C_S288C | rna-NM_001180949.1_S288C | cds-NP_011431.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000089.1:28030-29712:- | gene-YGL084C_SA1 | rna-NM_001180949.1_SA1 | cds-NP_011431.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:345519-347201:- | gene-YGL084C_ThermosaccDry | rna-NM_001180949.1_ThermosaccDry | cds-NP_011431.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:455382-457064:- | gene-YGL084C_VR1 | rna-NM_001180949.1_VR1 | cds-NP_011431.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:342884-344566:- | gene-YGL084C_ZTW1 | rna-NM_001180949.1_ZTW1 | cds-NP_011431.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:348509-350191:- | gene-YGL084C_Sparadoxus | rna-NM_001180949.1_Sparadoxus | cds-NP_011431.1_Sparadoxus | 90.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |