Gene name: GUK1
Reference locus (S288C): YDR454C
Gene biotype: protein_coding
Description: Guanylate kinase; converts GMP to GDP; required for growth and mannose outer chain elongation of cell wall N-linked glycoproteins
Top 10 interactors (score): HPT1 (0.985); GUA1 (0.984); HAM1 (0.983); RPO26 (0.965); YNK1 (0.964); APT1 (0.956); APT2 (0.95); RNR3 (0.938); RNR1 (0.938); PYK2 (0.933); CDC19 (0.933); RNR4 (0.929); PDE2 (0.921); RNR2 (0.918); YND1 (0.901); PDE1 (0.9); ADE12 (0.854); LIA1 (0.831); ADE13 (0.828); PRO3 (0.811)
Homologues (species, bitscore): GUK1 (Homo sapiens, 167.9); Guk1 (Mus musculus, 192.6); guk1a (Danio rerio, 196.1); guk1 (Xenopus tropicalis, 140.2); CG11811 (Drosophila melanogaster, 200.3); guk-1 (Caenorhabditis elegans, 204.5); GK-1 (Arabidopsis thaliana, 182.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1306170-1306733:- | gene-YDR454C_AKU4011 | rna-NM_001180762.1_AKU4011 | cds-NP_010742.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000039.1:184528-185091:- | gene-YDR454C_BG1 | rna-NM_001180762.1_BG1 | cds-NP_010742.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1337602-1338165:- | gene-YDR454C_Bruggeman | rna-NM_001180762.1_Bruggeman | cds-NP_010742.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1314751-1315314:- | gene-YDR454C_CAT1 | rna-NM_001180762.1_CAT1 | cds-NP_010742.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1300476-1301039:- | gene-YDR454C_CBS1585 | rna-NM_001180762.1_CBS1585 | cds-NP_010742.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1319849-1320412:- | gene-YDR454C_CBS436 | rna-NM_001180762.1_CBS436 | cds-NP_010742.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1296105-1296668:- | gene-YDR454C_CBS6412 | rna-NM_001180762.1_CBS6412 | cds-NP_010742.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1319116-1319679:- | gene-YDR454C_CBS6413 | rna-NM_001180762.1_CBS6413 | cds-NP_010742.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1364938-1365501:- | gene-YDR454C_CENPK1137D | rna-NM_001180762.1_CENPK1137D | cds-NP_010742.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1309526-1310089:- | gene-YDR454C_EthanolRed | rna-NM_001180762.1_EthanolRed | cds-NP_010742.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1313079-1313642:- | gene-YDR454C_FaliES1 | rna-NM_001180762.1_FaliES1 | cds-NP_010742.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000026.1:11337-11900:- | gene-YDR454C_JAY291 | rna-NM_001180762.1_JAY291 | cds-NP_010742.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1320091-1320654:- | gene-YDR454C_MUCL30387 | rna-NM_001180762.1_MUCL30387 | cds-NP_010742.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1302118-1302681:- | gene-YDR454C_MUCL30388 | rna-NM_001180762.1_MUCL30388 | cds-NP_010742.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1291960-1292523:- | gene-YDR454C_MUCL39482 | rna-NM_001180762.1_MUCL39482 | cds-NP_010742.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1234759-1235322:- | gene-YDR454C_MUCL42920 | rna-NM_001180762.1_MUCL42920 | cds-NP_010742.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1366187-1366750:- | gene-YDR454C_NCIM3186 | rna-NM_001180762.1_NCIM3186 | cds-NP_010742.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1305733-1306296:- | gene-YDR454C_NCYC1407 | rna-NM_001180762.1_NCYC1407 | cds-NP_010742.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1316586-1317149:- | gene-YDR454C_PE2H3 | rna-NM_001180762.1_PE2H3 | cds-NP_010742.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1322143-1322706:- | gene-YDR454C_PE2H4 | rna-NM_001180762.1_PE2H4 | cds-NP_010742.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1366264-1366827:- | gene-YDR454C_S288C | rna-NM_001180762.1_S288C | cds-NP_010742.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:250337-250900:+ | gene-YDR454C_SA1 | rna-NM_001180762.1_SA1 | cds-NP_010742.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1317301-1317864:- | gene-YDR454C_ThermosaccDry | rna-NM_001180762.1_ThermosaccDry | cds-NP_010742.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1333037-1333600:- | gene-YDR454C_VR1 | rna-NM_001180762.1_VR1 | cds-NP_010742.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:359977-360540:- | gene-YDR454C_ZTW1 | rna-NM_001180762.1_ZTW1 | cds-NP_010742.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1320400-1320963:- | gene-YDR454C_Sparadoxus | rna-NM_001180762.1_Sparadoxus | cds-NP_010742.1_Sparadoxus | 90.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |