GUF1 (YLR289W)


Gene profile

Gene name: GUF1
Reference locus (S288C): YLR289W
Gene biotype: protein_coding

Description: Translation factor GUF1, mitochondrial; Mitochondrial matrix GTPase; associates with mitochondrial ribosomes; important for translation under temperature and nutrient stress; may have a role in translational fidelity; similar to bacterial LepA elongation factor

Top 10 interactors (score): MRPL8 (0.981); MRPS9 (0.931); MTG2 (0.918); RPS3 (0.896); YNL122C (0.877); MRPS5 (0.872); IMG1 (0.869); RPL25 (0.864); PTH4 (0.863); MRPS16 (0.857); MRP7 (0.85); MRP17 (0.847); RPL5 (0.842); MRPL9 (0.842); MRPL24 (0.823); MRPL32 (0.812); RPS2 (0.802); RPL3 (0.799); OMS1 (0.793); MRPL39 (0.788)

Homologues (species, bitscore): GUF1 (Homo sapiens, 609.8); Guf1 (Mus musculus, 608.2); guf1 (Danio rerio, 599.0); guf1 (Xenopus tropicalis, 581.3); waw (Drosophila melanogaster, 527.3); ZK1236.1 (Caenorhabditis elegans, 481.5); AT5G39900 (Arabidopsis thaliana, 656.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:663888-665825:+ gene-YLR289W_AKU4011 rna-NM_001182177.1_AKU4011 cds-NP_013392.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000170.1:66866-68803:- gene-YLR289W_BG1 rna-NM_001182177.1_BG1 cds-NP_013392.1_BG1 99.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:699068-701005:+ gene-YLR289W_Bruggeman rna-NM_001182177.1_Bruggeman cds-NP_013392.1_Bruggeman 99.3 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:697637-699574:+ gene-YLR289W_CAT1 rna-NM_001182177.1_CAT1 cds-NP_013392.1_CAT1 99.2 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:698824-700761:+ gene-YLR289W_CBS1585 rna-NM_001182177.1_CBS1585 cds-NP_013392.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:683415-685352:+ gene-YLR289W_CBS436 rna-NM_001182177.1_CBS436 cds-NP_013392.1_CBS436 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:661457-663394:+ gene-YLR289W_CBS6412 rna-NM_001182177.1_CBS6412 cds-NP_013392.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:699489-701426:+ gene-YLR289W_CBS6413 rna-NM_001182177.1_CBS6413 cds-NP_013392.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:699687-701624:+ gene-YLR289W_CENPK1137D rna-NM_001182177.1_CENPK1137D cds-NP_013392.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:657167-659104:+ gene-YLR289W_EthanolRed rna-NM_001182177.1_EthanolRed cds-NP_013392.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:686367-688304:+ gene-YLR289W_FaliES1 rna-NM_001182177.1_FaliES1 cds-NP_013392.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000359.1:17466-19403:- gene-YLR289W_JAY291 rna-NM_001182177.1_JAY291 cds-NP_013392.1_JAY291 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:698959-700896:+ gene-YLR289W_MUCL30387 rna-NM_001182177.1_MUCL30387 cds-NP_013392.1_MUCL30387 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:704540-706477:+ gene-YLR289W_MUCL30388 rna-NM_001182177.1_MUCL30388 cds-NP_013392.1_MUCL30388 99.2 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:700055-701992:+ gene-YLR289W_MUCL39482 rna-NM_001182177.1_MUCL39482 cds-NP_013392.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:695208-697145:+ gene-YLR289W_MUCL42920 rna-NM_001182177.1_MUCL42920 cds-NP_013392.1_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:715063-717000:+ gene-YLR289W_NCIM3186 rna-NM_001182177.1_NCIM3186 cds-NP_013392.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:709386-711323:+ gene-YLR289W_NCYC1407 rna-NM_001182177.1_NCYC1407 cds-NP_013392.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:697184-699121:+ gene-YLR289W_PE2H3 rna-NM_001182177.1_PE2H3 cds-NP_013392.1_PE2H3 99.5 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:696928-698865:+ gene-YLR289W_PE2H4 rna-NM_001182177.1_PE2H4 cds-NP_013392.1_PE2H4 99.5 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:715089-717026:+ gene-YLR289W_S288C rna-NM_001182177.1_S288C cds-NP_013392.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000039.1:67664-69601:- gene-YLR289W_SA1 rna-NM_001182177.1_SA1 cds-NP_013392.1_SA1 99.5 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:688262-690199:+ gene-YLR289W_ThermosaccDry rna-NM_001182177.1_ThermosaccDry cds-NP_013392.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:700149-702086:+ gene-YLR289W_VR1 rna-NM_001182177.1_VR1 cds-NP_013392.1_VR1 99.3 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000025.1:26697-28634:+ gene-YLR289W_ZTW1 rna-NM_001182177.1_ZTW1 cds-NP_013392.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:674328-676265:+ gene-YLR289W_Sparadoxus rna-NM_001182177.1_Sparadoxus cds-NP_013392.1_Sparadoxus 91.6 100.0 Verified 1 1 1 False True False False False

Additional files