Gene name: GUF1
Reference locus (S288C): YLR289W
Gene biotype: protein_coding
Description: Translation factor GUF1, mitochondrial; Mitochondrial matrix GTPase; associates with mitochondrial ribosomes; important for translation under temperature and nutrient stress; may have a role in translational fidelity; similar to bacterial LepA elongation factor
Top 10 interactors (score): MRPL8 (0.981); MRPS9 (0.931); MTG2 (0.918); RPS3 (0.896); YNL122C (0.877); MRPS5 (0.872); IMG1 (0.869); RPL25 (0.864); PTH4 (0.863); MRPS16 (0.857); MRP7 (0.85); MRP17 (0.847); RPL5 (0.842); MRPL9 (0.842); MRPL24 (0.823); MRPL32 (0.812); RPS2 (0.802); RPL3 (0.799); OMS1 (0.793); MRPL39 (0.788)
Homologues (species, bitscore): GUF1 (Homo sapiens, 609.8); Guf1 (Mus musculus, 608.2); guf1 (Danio rerio, 599.0); guf1 (Xenopus tropicalis, 581.3); waw (Drosophila melanogaster, 527.3); ZK1236.1 (Caenorhabditis elegans, 481.5); AT5G39900 (Arabidopsis thaliana, 656.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:663888-665825:+ | gene-YLR289W_AKU4011 | rna-NM_001182177.1_AKU4011 | cds-NP_013392.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000170.1:66866-68803:- | gene-YLR289W_BG1 | rna-NM_001182177.1_BG1 | cds-NP_013392.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:699068-701005:+ | gene-YLR289W_Bruggeman | rna-NM_001182177.1_Bruggeman | cds-NP_013392.1_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:697637-699574:+ | gene-YLR289W_CAT1 | rna-NM_001182177.1_CAT1 | cds-NP_013392.1_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:698824-700761:+ | gene-YLR289W_CBS1585 | rna-NM_001182177.1_CBS1585 | cds-NP_013392.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:683415-685352:+ | gene-YLR289W_CBS436 | rna-NM_001182177.1_CBS436 | cds-NP_013392.1_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:661457-663394:+ | gene-YLR289W_CBS6412 | rna-NM_001182177.1_CBS6412 | cds-NP_013392.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:699489-701426:+ | gene-YLR289W_CBS6413 | rna-NM_001182177.1_CBS6413 | cds-NP_013392.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:699687-701624:+ | gene-YLR289W_CENPK1137D | rna-NM_001182177.1_CENPK1137D | cds-NP_013392.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:657167-659104:+ | gene-YLR289W_EthanolRed | rna-NM_001182177.1_EthanolRed | cds-NP_013392.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:686367-688304:+ | gene-YLR289W_FaliES1 | rna-NM_001182177.1_FaliES1 | cds-NP_013392.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000359.1:17466-19403:- | gene-YLR289W_JAY291 | rna-NM_001182177.1_JAY291 | cds-NP_013392.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:698959-700896:+ | gene-YLR289W_MUCL30387 | rna-NM_001182177.1_MUCL30387 | cds-NP_013392.1_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:704540-706477:+ | gene-YLR289W_MUCL30388 | rna-NM_001182177.1_MUCL30388 | cds-NP_013392.1_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:700055-701992:+ | gene-YLR289W_MUCL39482 | rna-NM_001182177.1_MUCL39482 | cds-NP_013392.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:695208-697145:+ | gene-YLR289W_MUCL42920 | rna-NM_001182177.1_MUCL42920 | cds-NP_013392.1_MUCL42920 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:715063-717000:+ | gene-YLR289W_NCIM3186 | rna-NM_001182177.1_NCIM3186 | cds-NP_013392.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:709386-711323:+ | gene-YLR289W_NCYC1407 | rna-NM_001182177.1_NCYC1407 | cds-NP_013392.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:697184-699121:+ | gene-YLR289W_PE2H3 | rna-NM_001182177.1_PE2H3 | cds-NP_013392.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:696928-698865:+ | gene-YLR289W_PE2H4 | rna-NM_001182177.1_PE2H4 | cds-NP_013392.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:715089-717026:+ | gene-YLR289W_S288C | rna-NM_001182177.1_S288C | cds-NP_013392.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000039.1:67664-69601:- | gene-YLR289W_SA1 | rna-NM_001182177.1_SA1 | cds-NP_013392.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:688262-690199:+ | gene-YLR289W_ThermosaccDry | rna-NM_001182177.1_ThermosaccDry | cds-NP_013392.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:700149-702086:+ | gene-YLR289W_VR1 | rna-NM_001182177.1_VR1 | cds-NP_013392.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000025.1:26697-28634:+ | gene-YLR289W_ZTW1 | rna-NM_001182177.1_ZTW1 | cds-NP_013392.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:674328-676265:+ | gene-YLR289W_Sparadoxus | rna-NM_001182177.1_Sparadoxus | cds-NP_013392.1_Sparadoxus | 91.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |