GTS1 (YGL181W)


Gene profile

Gene name: GTS1
Reference locus (S288C): YGL181W
Gene biotype: protein_coding

Description: Protein involved in Arf3p regulation and in transcription regulation; localizes to the nucleus and to endocytic patches; contains an N-terminal Zn-finger and ArfGAP homology domain, a C-terminal glutamine-rich region, and a UBA (ubiquitin associated) domain; gts1 mutations affect budding, cell size, heat tolerance, sporulation, life span, ultradian rhythms, endocytosis; expression oscillates in a pattern similar to metabolic oscillations

Top 10 interactors (score): CEF1 (0.999); ARF3 (0.969); PRP22 (0.921); YSC84 (0.874); ARL1 (0.872); PAN1 (0.87); SLA1 (0.849); LSB3 (0.816); POG1 (0.77); LSB5 (0.767); YEL1 (0.766); GEA2 (0.758); INP52 (0.755); YAP1802 (0.718); FLO1 (0.71); YAP1801 (0.707); RVS167 (0.705); GEA1 (0.699); CLC1 (0.679); BSP1 (0.674)

Homologues (species, bitscore): SMAP2 (Homo sapiens, 74.7); Smap2 (Mus musculus, 75.1); smap1 (Danio rerio, 75.1); smap1 (Xenopus tropicalis, 71.2); CG8243 (Drosophila melanogaster, 68.2); W09D10.1 (Caenorhabditis elegans, 68.6); AGD5 (Arabidopsis thaliana, 71.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:160422-161642:+ gene-YGL181W_AKU4011 rna-NM_001181046.1_AKU4011 cds-NP_011334.1_AKU4011 95.1 98.9 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000132.1:248795-249979:- gene-YGL181W_BG1 rna-NM_001181046.1_BG1 cds-NP_011334.1_BG1 99.1 99.4 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:162664-163872:+ gene-YGL181W_Bruggeman rna-NM_001181046.1_Bruggeman cds-NP_011334.1_Bruggeman 97.2 99.4 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:158539-159729:+ gene-YGL181W_CAT1 rna-NM_001181046.1_CAT1 cds-NP_011334.1_CAT1 99.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:163567-164787:+ gene-YGL181W_CBS1585 rna-NM_001181046.1_CBS1585 cds-NP_011334.1_CBS1585 95.0 98.9 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:158545-159759:+ gene-YGL181W_CBS436 rna-NM_001181046.1_CBS436 cds-NP_011334.1_CBS436 97.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:150347-151567:+ gene-YGL181W_CBS6412 rna-NM_001181046.1_CBS6412 cds-NP_011334.1_CBS6412 94.8 98.9 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:157876-159096:+ gene-YGL181W_CBS6413 rna-NM_001181046.1_CBS6413 cds-NP_011334.1_CBS6413 95.1 98.9 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:158097-159287:+ gene-YGL181W_CENPK1137D rna-NM_001181046.1_CENPK1137D cds-NP_011334.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:150216-151460:+ gene-YGL181W_EthanolRed rna-NM_001181046.1_EthanolRed cds-NP_011334.1_EthanolRed 94.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:151463-152707:+ gene-YGL181W_FaliES1 rna-NM_001181046.1_FaliES1 cds-NP_011334.1_FaliES1 94.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000090.1:1771-2955:+ gene-YGL181W_JAY291 rna-NM_001181046.1_JAY291 cds-NP_011334.1_JAY291 99.1 99.4 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:159898-161106:+ gene-YGL181W_MUCL30387 rna-NM_001181046.1_MUCL30387 cds-NP_011334.1_MUCL30387 97.2 99.4 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:162999-164207:+ gene-YGL181W_MUCL30388 rna-NM_001181046.1_MUCL30388 cds-NP_011334.1_MUCL30388 97.2 99.4 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:160571-161791:+ gene-YGL181W_MUCL39482 rna-NM_001181046.1_MUCL39482 cds-NP_011334.1_MUCL39482 95.1 98.9 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:163205-164413:+ gene-YGL181W_MUCL42920 rna-NM_001181046.1_MUCL42920 cds-NP_011334.1_MUCL42920 97.2 99.4 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:157906-159096:+ gene-YGL181W_NCIM3186 rna-NM_001181046.1_NCIM3186 cds-NP_011334.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:152058-153278:+ gene-YGL181W_NCYC1407 rna-NM_001181046.1_NCYC1407 cds-NP_011334.1_NCYC1407 94.8 98.9 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:154063-155253:+ gene-YGL181W_PE2H3 rna-NM_001181046.1_PE2H3 cds-NP_011334.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:153611-154801:+ gene-YGL181W_PE2H4 rna-NM_001181046.1_PE2H4 cds-NP_011334.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:157906-159096:+ gene-YGL181W_S288C rna-NM_001181046.1_S288C cds-NP_011334.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000067.1:17664-18854:+ gene-YGL181W_SA1 rna-NM_001181046.1_SA1 cds-NP_011334.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:151693-152937:+ gene-YGL181W_ThermosaccDry rna-NM_001181046.1_ThermosaccDry cds-NP_011334.1_ThermosaccDry 94.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:158965-160155:+ gene-YGL181W_VR1 rna-NM_001181046.1_VR1 cds-NP_011334.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000014.1:150213-151373:+ gene-YGL181W_ZTW1 rna-NM_001181046.1_ZTW1 cds-NP_011334.1_ZTW1 96.8 97.4 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:157043-158248:+ gene-YGL181W_Sparadoxus rna-NM_001181046.1_Sparadoxus cds-NP_011334.1_Sparadoxus 88.9 99.7 Verified 1 1 1 False True False False False

Additional files