Gene name: GTR2
Reference locus (S288C): YGR163W
Gene biotype: protein_coding
Description: GTP-binding protein GTR2; Subunit of a TORC1-stimulating GTPase complex; subunit of the Gtr1-Gtr2 GTPase complex that stimulates TORC1 in response to amino acid stimulation; stimulates the GTPase activity of Gtr1p; negatively regulates the Ran/Tc4 GTPase cycle; activates transcription; tethered to the vacuolar membrane as part of the EGO complex (EGOC); required for sorting of Gap1p; activated by the the Lst4p-Lst7p GAP complex; localizes to cytoplasm and to chromatin; homolog of human RagC and
Top 10 interactors (score): KOG1 (0.999); MEH1 (0.999); SLM4 (0.999); TOR1 (0.999); GTR1 (0.999); TOR2 (0.998); EGO2 (0.994); LST8 (0.986); NPR2 (0.985); RHB1 (0.979); PIB2 (0.971); LST7 (0.969); VMA1 (0.953); IML1 (0.938); NAM2 (0.924); RTC1 (0.915); VAM6 (0.914); VMA2 (0.906); LTV1 (0.906); MTC5 (0.902)
Homologues (species, bitscore): RRAGC (Homo sapiens, 305.1); Rragc (Mus musculus, 305.1); rragd (Danio rerio, 302.8); rragd (Xenopus tropicalis, 305.1); RagC-D (Drosophila melanogaster, 293.9); ragc-1 (Caenorhabditis elegans, 223.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:795301-796326:+ | gene-YGR163W_AKU4011 | rna-NM_001181292.3_AKU4011 | cds-NP_011679.3_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:73431-74456:+ | gene-YGR163W_BG1 | rna-NM_001181292.3_BG1 | cds-NP_011679.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:801232-802257:+ | gene-YGR163W_Bruggeman | rna-NM_001181292.3_Bruggeman | cds-NP_011679.3_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:797084-798109:+ | gene-YGR163W_CAT1 | rna-NM_001181292.3_CAT1 | cds-NP_011679.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:796017-797042:+ | gene-YGR163W_CBS1585 | rna-NM_001181292.3_CBS1585 | cds-NP_011679.3_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:799915-800940:+ | gene-YGR163W_CBS436 | rna-NM_001181292.3_CBS436 | cds-NP_011679.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:787386-788411:+ | gene-YGR163W_CBS6412 | rna-NM_001181292.3_CBS6412 | cds-NP_011679.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:792881-793906:+ | gene-YGR163W_CBS6413 | rna-NM_001181292.3_CBS6413 | cds-NP_011679.3_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:827287-828312:+ | gene-YGR163W_CENPK1137D | rna-NM_001181292.3_CENPK1137D | cds-NP_011679.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:781403-782428:+ | gene-YGR163W_EthanolRed | rna-NM_001181292.3_EthanolRed | cds-NP_011679.3_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:785793-786818:+ | gene-YGR163W_FaliES1 | rna-NM_001181292.3_FaliES1 | cds-NP_011679.3_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000112.1:28207-29232:+ | gene-YGR163W_JAY291 | rna-NM_001181292.3_JAY291 | cds-NP_011679.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:798723-799748:+ | gene-YGR163W_MUCL30387 | rna-NM_001181292.3_MUCL30387 | cds-NP_011679.3_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:798421-799446:+ | gene-YGR163W_MUCL30388 | rna-NM_001181292.3_MUCL30388 | cds-NP_011679.3_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:791592-792617:+ | gene-YGR163W_MUCL39482 | rna-NM_001181292.3_MUCL39482 | cds-NP_011679.3_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:806553-807578:+ | gene-YGR163W_MUCL42920 | rna-NM_001181292.3_MUCL42920 | cds-NP_011679.3_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:827552-828577:+ | gene-YGR163W_NCIM3186 | rna-NM_001181292.3_NCIM3186 | cds-NP_011679.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:786700-787725:+ | gene-YGR163W_NCYC1407 | rna-NM_001181292.3_NCYC1407 | cds-NP_011679.3_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:805900-806925:+ | gene-YGR163W_PE2H3 | rna-NM_001181292.3_PE2H3 | cds-NP_011679.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:811010-812035:+ | gene-YGR163W_PE2H4 | rna-NM_001181292.3_PE2H4 | cds-NP_011679.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:827552-828577:+ | gene-YGR163W_S288C | rna-NM_001181292.3_S288C | cds-NP_011679.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000035.1:51201-52226:+ | gene-YGR163W_SA1 | rna-NM_001181292.3_SA1 | cds-NP_011679.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:806304-807329:+ | gene-YGR163W_ThermosaccDry | rna-NM_001181292.3_ThermosaccDry | cds-NP_011679.3_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:911050-912075:+ | gene-YGR163W_VR1 | rna-NM_001181292.3_VR1 | cds-NP_011679.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:108237-109262:+ | gene-YGR163W_ZTW1 | rna-NM_001181292.3_ZTW1 | cds-NP_011679.3_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:792376-793401:- | gene-YGR163W_Sparadoxus | rna-NM_001181292.3_Sparadoxus | cds-NP_011679.3_Sparadoxus | 90.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |