Gene name: GTR1
Reference locus (S288C): YML121W
Gene biotype: protein_coding
Description: GTP-binding protein GTR1; Subunit of a TORC1-stimulating GTPase complex; subunit of the heterodimeric Gtr1-Gtr2 GTPase complex that stimulates TORC1 in response to amino acid stimulation; tethered to the vacuolar membrane as part of the EGOC, a complex required for sorting of Gap1p and microautophagy; involved in phosphate transport and telomeric chromatin silencing; activated by the the Iml1p (GAP) subunit of the SEACIT complex; similar to human RagA and RagB
Top 10 interactors (score): KOG1 (0.999); NPR2 (0.999); TOR2 (0.999); TOR1 (0.999); GTR2 (0.999); SLM4 (0.999); MEH1 (0.999); EGO2 (0.996); IML1 (0.995); VMA1 (0.993); LST8 (0.991); RHB1 (0.976); VAM6 (0.971); PIB2 (0.963); LST7 (0.959); TCO89 (0.956); VMA2 (0.954); CDC60 (0.953); RTC1 (0.951); SRM1 (0.945)
Homologues (species, bitscore): RRAGA (Homo sapiens, 311.6); Rraga (Mus musculus, 311.6); rraga (Danio rerio, 252.7); rraga (Xenopus tropicalis, 300.4); RagA-B (Drosophila melanogaster, 299.7); raga-1 (Caenorhabditis elegans, 287.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:20628-21560:+ | gene-YML121W_AKU4011 | rna-NM_001182484.1_AKU4011 | cds-NP_013585.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:454609-455541:- | gene-YML121W_BG1 | rna-NM_001182484.1_BG1 | cds-NP_013585.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:26840-27772:+ | gene-YML121W_Bruggeman | rna-NM_001182484.1_Bruggeman | cds-NP_013585.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:28450-29382:+ | gene-YML121W_CAT1 | rna-NM_001182484.1_CAT1 | cds-NP_013585.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:20627-21559:+ | gene-YML121W_CBS1585 | rna-NM_001182484.1_CBS1585 | cds-NP_013585.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:26600-27532:+ | gene-YML121W_CBS436 | rna-NM_001182484.1_CBS436 | cds-NP_013585.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:21390-22322:+ | gene-YML121W_CBS6412 | rna-NM_001182484.1_CBS6412 | cds-NP_013585.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:19854-20786:+ | gene-YML121W_CBS6413 | rna-NM_001182484.1_CBS6413 | cds-NP_013585.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:21445-22377:+ | gene-YML121W_CENPK1137D | rna-NM_001182484.1_CENPK1137D | cds-NP_013585.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:21143-22075:+ | gene-YML121W_EthanolRed | rna-NM_001182484.1_EthanolRed | cds-NP_013585.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:21420-22352:+ | gene-YML121W_FaliES1 | rna-NM_001182484.1_FaliES1 | cds-NP_013585.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000345.1:67879-68811:- | gene-YML121W_JAY291 | rna-NM_001182484.1_JAY291 | cds-NP_013585.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:24863-25795:+ | gene-YML121W_MUCL30387 | rna-NM_001182484.1_MUCL30387 | cds-NP_013585.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:28534-29466:+ | gene-YML121W_MUCL30388 | rna-NM_001182484.1_MUCL30388 | cds-NP_013585.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:20642-21574:+ | gene-YML121W_MUCL39482 | rna-NM_001182484.1_MUCL39482 | cds-NP_013585.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:24308-25240:+ | gene-YML121W_MUCL42920 | rna-NM_001182484.1_MUCL42920 | cds-NP_013585.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:26884-27816:+ | gene-YML121W_NCIM3186 | rna-NM_001182484.1_NCIM3186 | cds-NP_013585.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:21437-22369:+ | gene-YML121W_NCYC1407 | rna-NM_001182484.1_NCYC1407 | cds-NP_013585.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:26830-27762:+ | gene-YML121W_PE2H3 | rna-NM_001182484.1_PE2H3 | cds-NP_013585.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:26768-27700:+ | gene-YML121W_PE2H4 | rna-NM_001182484.1_PE2H4 | cds-NP_013585.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:26930-27862:+ | gene-YML121W_S288C | rna-NM_001182484.1_S288C | cds-NP_013585.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000054.1:18875-19807:+ | gene-YML121W_SA1 | rna-NM_001182484.1_SA1 | cds-NP_013585.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:20718-21650:+ | gene-YML121W_ThermosaccDry | rna-NM_001182484.1_ThermosaccDry | cds-NP_013585.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:25119-26051:+ | gene-YML121W_VR1 | rna-NM_001182484.1_VR1 | cds-NP_013585.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:201-1133:+ | gene-YML121W_ZTW1 | rna-NM_001182484.1_ZTW1 | cds-NP_013585.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:31734-32666:+ | gene-YML121W_Sparadoxus | rna-NM_001182484.1_Sparadoxus | cds-NP_013585.1_Sparadoxus | 92.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |