GTB1 (YDR221W)


Gene profile

Gene name: GTB1
Reference locus (S288C): YDR221W
Gene biotype: protein_coding

Description: Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p; involved in removal of two glucose residues from N-linked glycans during glycoprotein biogenesis in the ER; relocalizes from ER to cytoplasm upon DNA replication stress

Top 10 interactors (score): ROT2 (0.999); CWH41 (0.913); SEC63 (0.909); MNS1 (0.9); KRE5 (0.836); MRL1 (0.82); WBP1 (0.77); CNE1 (0.761); YOS9 (0.726); ISW1 (0.627); SWP1 (0.626); CSE1 (0.602); NAN1 (0.598); ENP1 (0.583); PRC1 (0.578); DPB11 (0.573); GPI11 (0.568); HRD3 (0.567); SEC16 (0.56); NAR1 (0.533)

Homologues (species, bitscore): PRKCSH (Homo sapiens, 85.5); Prkcsh (Mus musculus, 88.2); prkcsh (Danio rerio, 92.8); prkcsh (Xenopus tropicalis, 73.2); CG6453 (Drosophila melanogaster, 103.6); ZK1307.8 (Caenorhabditis elegans, 87.4); PSL4 (Arabidopsis thaliana, 73.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:864029-866137:+ gene-YDR221W_AKU4011 rna-NM_001180529.3_AKU4011 cds-NP_010507.3_AKU4011 99.1 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:259695-261803:- gene-YDR221W_BG1 rna-NM_001180529.3_BG1 cds-NP_010507.3_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:896351-898459:+ gene-YDR221W_Bruggeman rna-NM_001180529.3_Bruggeman cds-NP_010507.3_Bruggeman 99.1 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:883624-885732:+ gene-YDR221W_CAT1 rna-NM_001180529.3_CAT1 cds-NP_010507.3_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:854381-856489:+ gene-YDR221W_CBS1585 rna-NM_001180529.3_CBS1585 cds-NP_010507.3_CBS1585 99.0 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:883390-885498:+ gene-YDR221W_CBS436 rna-NM_001180529.3_CBS436 cds-NP_010507.3_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:851140-853248:+ gene-YDR221W_CBS6412 rna-NM_001180529.3_CBS6412 cds-NP_010507.3_CBS6412 99.0 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:881740-883848:+ gene-YDR221W_CBS6413 rna-NM_001180529.3_CBS6413 cds-NP_010507.3_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:906132-908240:+ gene-YDR221W_CENPK1137D rna-NM_001180529.3_CENPK1137D cds-NP_010507.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:864723-866831:+ gene-YDR221W_EthanolRed rna-NM_001180529.3_EthanolRed cds-NP_010507.3_EthanolRed 99.0 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:872924-875032:+ gene-YDR221W_FaliES1 rna-NM_001180529.3_FaliES1 cds-NP_010507.3_FaliES1 99.0 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000348.1:36541-38649:- gene-YDR221W_JAY291 rna-NM_001180529.3_JAY291 cds-NP_010507.3_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:882002-884110:+ gene-YDR221W_MUCL30387 rna-NM_001180529.3_MUCL30387 cds-NP_010507.3_MUCL30387 99.1 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:870256-872364:+ gene-YDR221W_MUCL30388 rna-NM_001180529.3_MUCL30388 cds-NP_010507.3_MUCL30388 99.1 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:855790-857898:+ gene-YDR221W_MUCL39482 rna-NM_001180529.3_MUCL39482 cds-NP_010507.3_MUCL39482 99.0 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:795071-797179:+ gene-YDR221W_MUCL42920 rna-NM_001180529.3_MUCL42920 cds-NP_010507.3_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:907253-909361:+ gene-YDR221W_NCIM3186 rna-NM_001180529.3_NCIM3186 cds-NP_010507.3_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:859455-861563:+ gene-YDR221W_NCYC1407 rna-NM_001180529.3_NCYC1407 cds-NP_010507.3_NCYC1407 99.1 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:875681-877789:+ gene-YDR221W_PE2H3 rna-NM_001180529.3_PE2H3 cds-NP_010507.3_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:880963-883071:+ gene-YDR221W_PE2H4 rna-NM_001180529.3_PE2H4 cds-NP_010507.3_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:907330-909438:+ gene-YDR221W_S288C rna-NM_001180529.3_S288C cds-NP_010507.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000013.1:113437-115545:+ gene-YDR221W_SA1 rna-NM_001180529.3_SA1 cds-NP_010507.3_SA1 99.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:871080-873188:+ gene-YDR221W_ThermosaccDry rna-NM_001180529.3_ThermosaccDry cds-NP_010507.3_ThermosaccDry 99.0 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:886286-888394:+ gene-YDR221W_VR1 rna-NM_001180529.3_VR1 cds-NP_010507.3_VR1 99.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000007.1:133798-135906:+ gene-YDR221W_ZTW1 rna-NM_001180529.3_ZTW1 cds-NP_010507.3_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:876215-878323:+ gene-YDR221W_Sparadoxus rna-NM_001180529.3_Sparadoxus cds-NP_010507.3_Sparadoxus 85.6 100.0 Verified 1 1 1 False True False False False

Additional files