Gene name: GSP2
Reference locus (S288C): YOR185C
Gene biotype: protein_coding
Description: GTP-binding nuclear protein GSP2/CNR2; GTP binding protein (mammalian Ranp homolog); involved in the maintenance of nuclear organization, RNA processing and transport; interacts with Kap121p, Kap123p and Pdr6p (karyophilin betas); not required for viability; protein abundance increases in response to DNA replication stress; GSP2 has a paralog, GSP1, that arose from the whole genome duplication; Belongs to the small GTPase superfamily. Ran family
Top 10 interactors (score): SRM1 (0.999); NUP2 (0.999); CRM1 (0.999); KAP95 (0.998); NTF2 (0.998); YRB1 (0.997); MSN5 (0.991); CSE1 (0.986); MOG1 (0.986); RNA1 (0.984); KAP122 (0.975); KAP123 (0.975); LOS1 (0.972); TIF11 (0.964); SNF5 (0.963); NSP1 (0.962); GSP1 (0.946); KAP104 (0.923); HTZ1 (0.904); PSE1 (0.904)
Homologues (species, bitscore): RAN (Homo sapiens, 365.9); Ran (Mus musculus, 365.9); ran (Danio rerio, 364.4); ran (Xenopus tropicalis, 365.9); Ran (Drosophila melanogaster, 365.5); ran-1 (Caenorhabditis elegans, 373.6); RAN3 (Arabidopsis thaliana, 355.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:678772-679434:- | gene-YOR185C_AKU4011 | rna-NM_001183604.1_AKU4011 | cds-NP_014828.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:80829-81491:- | gene-YOR185C_BG1 | rna-NM_001183604.1_BG1 | cds-NP_014828.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:662785-663447:- | gene-YOR185C_Bruggeman | rna-NM_001183604.1_Bruggeman | cds-NP_014828.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:663960-664622:- | gene-YOR185C_CAT1 | rna-NM_001183604.1_CAT1 | cds-NP_014828.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:661761-662423:- | gene-YOR185C_CBS1585 | rna-NM_001183604.1_CBS1585 | cds-NP_014828.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:659880-660542:- | gene-YOR185C_CBS436 | rna-NM_001183604.1_CBS436 | cds-NP_014828.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:658877-659539:- | gene-YOR185C_CBS6412 | rna-NM_001183604.1_CBS6412 | cds-NP_014828.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:667518-668180:- | gene-YOR185C_CBS6413 | rna-NM_001183604.1_CBS6413 | cds-NP_014828.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:681194-681856:- | gene-YOR185C_CENPK1137D | rna-NM_001183604.1_CENPK1137D | cds-NP_014828.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:654749-655411:- | gene-YOR185C_EthanolRed | rna-NM_001183604.1_EthanolRed | cds-NP_014828.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:659822-660484:- | gene-YOR185C_FaliES1 | rna-NM_001183604.1_FaliES1 | cds-NP_014828.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000038.1:17056-17718:+ | gene-YOR185C_JAY291 | rna-NM_001183604.1_JAY291 | cds-NP_014828.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:667590-668252:- | gene-YOR185C_MUCL30387 | rna-NM_001183604.1_MUCL30387 | cds-NP_014828.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:675006-675668:- | gene-YOR185C_MUCL30388 | rna-NM_001183604.1_MUCL30388 | cds-NP_014828.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:669091-669753:- | gene-YOR185C_MUCL39482 | rna-NM_001183604.1_MUCL39482 | cds-NP_014828.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:678477-679139:- | gene-YOR185C_MUCL42920 | rna-NM_001183604.1_MUCL42920 | cds-NP_014828.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:681333-681995:- | gene-YOR185C_NCIM3186 | rna-NM_001183604.1_NCIM3186 | cds-NP_014828.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:669188-669850:- | gene-YOR185C_NCYC1407 | rna-NM_001183604.1_NCYC1407 | cds-NP_014828.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:668013-668675:- | gene-YOR185C_PE2H3 | rna-NM_001183604.1_PE2H3 | cds-NP_014828.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:678390-679052:- | gene-YOR185C_PE2H4 | rna-NM_001183604.1_PE2H4 | cds-NP_014828.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:681444-682106:- | gene-YOR185C_S288C | rna-NM_001183604.1_S288C | cds-NP_014828.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:98009-98671:- | gene-YOR185C_SA1 | rna-NM_001183604.1_SA1 | cds-NP_014828.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:659006-659668:- | gene-YOR185C_ThermosaccDry | rna-NM_001183604.1_ThermosaccDry | cds-NP_014828.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:723042-723704:- | gene-YOR185C_VR1 | rna-NM_001183604.1_VR1 | cds-NP_014828.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:392409-393071:- | gene-YOR185C_ZTW1 | rna-NM_001183604.1_ZTW1 | cds-NP_014828.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:664613-665275:- | gene-YOR185C_Sparadoxus | rna-NM_001183604.1_Sparadoxus | cds-NP_014828.1_Sparadoxus | 93.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |