GSH2 (YOL049W)


Gene profile

Gene name: GSH2
Reference locus (S288C): YOL049W
Gene biotype: protein_coding

Description: Glutathione synthetase; catalyzes the ATP-dependent synthesis of glutathione (GSH) from gamma-glutamylcysteine and glycine; induced by oxidative stress and heat shock

Top 10 interactors (score): GSH1 (0.999); GLR1 (0.994); ECM38 (0.991); RBK1 (0.962); NTF2 (0.962); GTT1 (0.934); DUG1 (0.927); URE2 (0.927); GCG1 (0.905); PRX1 (0.902); CYS4 (0.883); CTA1 (0.871); IRC15 (0.87); LPD1 (0.87); BAT2 (0.837); BAT1 (0.837); SHM2 (0.834); SHM1 (0.834); CTT1 (0.83); YAP1 (0.817)

Homologues (species, bitscore): GSS (Homo sapiens, 261.2); Gss (Mus musculus, 256.5); gss (Danio rerio, 260.8); gss (Xenopus tropicalis, 186.4); GS (Drosophila melanogaster, 238.8); gss-1 (Caenorhabditis elegans, 194.9); GSH2 (Arabidopsis thaliana, 270.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:222943-224418:+ gene-YOL049W_AKU4011 rna-NM_001183303.1_AKU4011 cds-NP_014593.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000152.1:38603-40078:+ gene-YOL049W_BG1 rna-NM_001183303.1_BG1 cds-NP_014593.1_BG1 99.7 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:225836-227311:+ gene-YOL049W_Bruggeman rna-NM_001183303.1_Bruggeman cds-NP_014593.1_Bruggeman 99.7 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:223691-225166:+ gene-YOL049W_CAT1 rna-NM_001183303.1_CAT1 cds-NP_014593.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:217611-219086:+ gene-YOL049W_CBS1585 rna-NM_001183303.1_CBS1585 cds-NP_014593.1_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:221930-223405:+ gene-YOL049W_CBS436 rna-NM_001183303.1_CBS436 cds-NP_014593.1_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:217008-218483:+ gene-YOL049W_CBS6412 rna-NM_001183303.1_CBS6412 cds-NP_014593.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:224527-226002:+ gene-YOL049W_CBS6413 rna-NM_001183303.1_CBS6413 cds-NP_014593.1_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:238320-239795:+ gene-YOL049W_CENPK1137D rna-NM_001183303.1_CENPK1137D cds-NP_014593.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:219963-221438:+ gene-YOL049W_EthanolRed rna-NM_001183303.1_EthanolRed cds-NP_014593.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:222879-224354:+ gene-YOL049W_FaliES1 rna-NM_001183303.1_FaliES1 cds-NP_014593.1_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000018.1:42099-43574:- gene-YOL049W_JAY291 rna-NM_001183303.1_JAY291 cds-NP_014593.1_JAY291 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:228859-230334:+ gene-YOL049W_MUCL30387 rna-NM_001183303.1_MUCL30387 cds-NP_014593.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:233206-234681:+ gene-YOL049W_MUCL30388 rna-NM_001183303.1_MUCL30388 cds-NP_014593.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:225129-226604:+ gene-YOL049W_MUCL39482 rna-NM_001183303.1_MUCL39482 cds-NP_014593.1_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:240070-241545:+ gene-YOL049W_MUCL42920 rna-NM_001183303.1_MUCL42920 cds-NP_014593.1_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:238508-239983:+ gene-YOL049W_NCIM3186 rna-NM_001183303.1_NCIM3186 cds-NP_014593.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:231873-233348:+ gene-YOL049W_NCYC1407 rna-NM_001183303.1_NCYC1407 cds-NP_014593.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:214297-215772:+ gene-YOL049W_PE2H3 rna-NM_001183303.1_PE2H3 cds-NP_014593.1_PE2H3 99.7 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:225271-226746:+ gene-YOL049W_PE2H4 rna-NM_001183303.1_PE2H4 cds-NP_014593.1_PE2H4 99.7 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:238619-240094:+ gene-YOL049W_S288C rna-NM_001183303.1_S288C cds-NP_014593.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000001.1:206620-208095:+ gene-YOL049W_SA1 rna-NM_001183303.1_SA1 cds-NP_014593.1_SA1 99.3 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:221450-222925:+ gene-YOL049W_ThermosaccDry rna-NM_001183303.1_ThermosaccDry cds-NP_014593.1_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:221522-222997:+ gene-YOL049W_VR1 rna-NM_001183303.1_VR1 cds-NP_014593.1_VR1 99.7 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000031.1:221323-222798:+ gene-YOL049W_ZTW1 rna-NM_001183303.1_ZTW1 cds-NP_014593.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:229700-231175:+ gene-YOL049W_Sparadoxus rna-NM_001183303.1_Sparadoxus cds-NP_014593.1_Sparadoxus 89.0 99.9 Verified 1 1 1 False True False False False

Additional files