Gene name: GRX3
Reference locus (S288C): YDR098C
Gene biotype: protein_coding
Description: Monothiol glutaredoxin-3; Glutathione-dependent oxidoreductase; hydroperoxide and superoxide-radical responsive; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage; with Grx4p, binds to Aft1p in iron-replete conditions, promoting its dissociation from promoters; evidence exists indicating that the translation start site is not Met1 as currently annotated, but rather Met36; GRX3 has a paralog, GRX4, that arose from the whole genome duplication
Top 10 interactors (score): BOL2 (0.999); DRE2 (0.998); AFT1 (0.995); BOL1 (0.986); BOL3 (0.964); GRX2 (0.962); AFT2 (0.956); GRX1 (0.941); ATM1 (0.905); NFU1 (0.905); NBP35 (0.888); ISU1 (0.887); TAH18 (0.876); FRA1 (0.87); MET18 (0.838); GRX7 (0.836); GRX8 (0.834); YAH1 (0.827); NAR1 (0.825); ISA2 (0.823)
Homologues (species, bitscore): GLRX3 (Homo sapiens, 164.1); Glrx3 (Mus musculus, 165.2); glrx3 (Danio rerio, 167.2); glrx3 (Xenopus tropicalis, 161.0); CG6523 (Drosophila melanogaster, 152.5); glrx-3 (Caenorhabditis elegans, 152.5); GRXS17 (Arabidopsis thaliana, 166.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:621734-622486:- | gene-YDR098C_AKU4011 | rna-NM_001180406.4_AKU4011 | cds-NP_010383.4_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:502792-503544:+ | gene-YDR098C_BG1 | rna-NM_001180406.4_BG1 | cds-NP_010383.4_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:653825-654577:- | gene-YDR098C_Bruggeman | rna-NM_001180406.4_Bruggeman | cds-NP_010383.4_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:638628-639380:- | gene-YDR098C_CAT1 | rna-NM_001180406.4_CAT1 | cds-NP_010383.4_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:612754-613506:- | gene-YDR098C_CBS1585 | rna-NM_001180406.4_CBS1585 | cds-NP_010383.4_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:637633-638385:- | gene-YDR098C_CBS436 | rna-NM_001180406.4_CBS436 | cds-NP_010383.4_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:609168-609920:- | gene-YDR098C_CBS6412 | rna-NM_001180406.4_CBS6412 | cds-NP_010383.4_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:637699-638451:- | gene-YDR098C_CBS6413 | rna-NM_001180406.4_CBS6413 | cds-NP_010383.4_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:643185-643937:- | gene-YDR098C_CENPK1137D | rna-NM_001180406.4_CENPK1137D | cds-NP_010383.4_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:623522-624274:- | gene-YDR098C_EthanolRed | rna-NM_001180406.4_EthanolRed | cds-NP_010383.4_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:630316-631068:- | gene-YDR098C_FaliES1 | rna-NM_001180406.4_FaliES1 | cds-NP_010383.4_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000358.1:336-1088:+ | gene-YDR098C_JAY291 | rna-NM_001180406.4_JAY291 | cds-NP_010383.4_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:638990-639742:- | gene-YDR098C_MUCL30387 | rna-NM_001180406.4_MUCL30387 | cds-NP_010383.4_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:628754-629506:- | gene-YDR098C_MUCL30388 | rna-NM_001180406.4_MUCL30388 | cds-NP_010383.4_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:614124-614876:- | gene-YDR098C_MUCL39482 | rna-NM_001180406.4_MUCL39482 | cds-NP_010383.4_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:545801-546553:- | gene-YDR098C_MUCL42920 | rna-NM_001180406.4_MUCL42920 | cds-NP_010383.4_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:644101-644853:- | gene-YDR098C_NCIM3186 | rna-NM_001180406.4_NCIM3186 | cds-NP_010383.4_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:613033-613785:- | gene-YDR098C_NCYC1407 | rna-NM_001180406.4_NCYC1407 | cds-NP_010383.4_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:632499-633251:- | gene-YDR098C_PE2H3 | rna-NM_001180406.4_PE2H3 | cds-NP_010383.4_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:631804-632556:- | gene-YDR098C_PE2H4 | rna-NM_001180406.4_PE2H4 | cds-NP_010383.4_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:644178-644930:- | gene-YDR098C_S288C | rna-NM_001180406.4_S288C | cds-NP_010383.4_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000011.1:408-1160:+ | gene-YDR098C_SA1 | rna-NM_001180406.4_SA1 | cds-NP_010383.4_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:629845-630597:- | gene-YDR098C_ThermosaccDry | rna-NM_001180406.4_ThermosaccDry | cds-NP_010383.4_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:642397-643149:- | gene-YDR098C_VR1 | rna-NM_001180406.4_VR1 | cds-NP_010383.4_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:627428-628180:- | gene-YDR098C_ZTW1 | rna-NM_001180406.4_ZTW1 | cds-NP_010383.4_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:631999-632751:- | gene-YDR098C_Sparadoxus | rna-NM_001180406.4_Sparadoxus | cds-NP_010383.4_Sparadoxus | 89.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |